Navigation Links
Memory Complaints Are Associated With Alzheimer's Disease

Complaints about memory could offer an early warning system for Alzheimer Disease - says a study done by researchers at Rush University Medical Center. The researchers have found// that having complaints about memory problems is associated with changes in the brain related to Alzheimer's disease. Their findings were published in the November 2006 issue of Neurology.

The researchers looked at the association between memory problems reported by study participants and signs of disease found in their brains after death. The study looked at autopsies of 90 older adults from the Rush Memory and Aging Project. The study included both participants who had been diagnosed with Alzheimer's disease (23) and those that showed no clinical signs of the disease (67).

'One of the most interesting findings of the study was that individuals who had yet to have any clinical symptoms of Alzheimer's disease still showed a strong link between their self-reported memory complaints and brain pathology associated with Alzheimer's disease,' said Lisa L. Barnes, PhD, from the Rush Alzheimer's Disease Center. 'This information may allow us to use memory complaints as a measure to intervene at an early point in the disease process.'

To measure memory complaints participants were asked two questions:
  • How often do you have trouble remembering things?

  • How is your memory [now] compared to 10 years ago?

  • The researchers combined the answers to these two questions to create a scale to measure the severity of memory complaints. They used the memory scores taken closest to time of death. They also adjusted for confounding factors that might be related to memory problems like age, sex, and level of education.

    The researchers then compared this scale with the levels of damage to the brain revealed during autopsy. The damage specifically looked at was the amount of amyloid plaques and tau tangles in the brain at the time of deat h. These plaques and tangles are the type of damage most closely linked to Alzheimer's disease.

    The researchers found that each unit of Alzheimer-related pathology was associated with one point higher score on the memory complaint scale. 'Our results suggest that older persons with and without dementia possess some insight to their level of functioning, and this insight is related to actual changes in the brain,' said Barnes. 'The data suggests that if you’re having complaints there's probably something going on. In other words, if mom notices that there's something different about her memory, we need to listen closely and investigate further.'

    The study shows that memory complaints should be taken seriously and not seen as just part of the aging process. 'In my opinion, it is possible to preserve your memory into old age,' said Barnes. 'Memory loss is not an inevitable consequence of aging.

    In fact, if you think you are having memory problems, you should probably see your doctor. As Barnes noted, 'although not all memory complaints will lead to Alzheimer's disease, our data support the idea that memory complaints in older adults may represent the presence of significant Alzheimer's disease pathology in the brain.'

    'I don't want to cause concern for people who experience occasional memory loss, like losing their keys or forgetting their wife's birthday,' said Barnes. 'The important point in our study was that the people who hadn't developed Alzheimer's disease by the time they died, but complained about their memory performance, already had Alzheimer's pathology in their brains. We don't know whether they might have eventually developed the disease had they lived longer. The data suggest, however, that memory complaints may be an early sign of disease in some people.'

    The researchers at Rush are grateful for the remarkable dedication and altruism of the volunteers participating in the Rush Memory and Aging Project. T he research was supported by grants from the National Institute on Aging, which leads the Federal effort to support and conduct basic, clinical, and social and behavioral studies on aging and on Alzheimer's disease.

    Source-Eurekalert
    SRI
    '"/>




    Related medicine news :

    1. Memory problem? solve a crossword
    2. Deep Sleep Doesnt Increase Memory
    3. For a Better Memory
    4. Memory loss associated with microbes
    5. Memory loss always goes hand with Depression
    6. Memory deprivation after operations
    7. Sage Improves Memory
    8. Memory said to automatically improve with age
    9. Enzyme Associated with Memory
    10. Enzyme Associated With Memory
    11. New Drug Combination Found To Improve Memory in Alzheimer’s Patient
    Post Your Comments:
    *Name:
    *Comment:
    *Email:


    (Date:5/2/2016)... ... May 02, 2016 , ... Those who may be ... find some useful information in a new video released by Serenity Recovery, a ... can be viewed on the Serenity Recovery YouTube channel, examines various treatment methods ...
    (Date:5/2/2016)... (PRWEB) , ... May 02, 2016 , ... Pets bring ... a token of appreciation, pet owners celebrate National Pet Week, which falls on the ... 2016, remind pet owners to cherish the human-animal bond and recognize responsible pet ownership. ...
    (Date:5/2/2016)... R.I. (PRWEB) , ... May 02, 2016 , ... ... an educational website to help consumers better understand life insurance throughout various life ... resources, including an easy-to-use life insurance needs calculator and content specific to the ...
    (Date:5/2/2016)... ... May 02, 2016 , ... WestHarbor Growth Partners, a ... the release of Grow Healthy Vending’s newly revamped brand campaign. Grow Healthy ... healthy vending providers in North America with locations across the United States as ...
    (Date:5/2/2016)... ... May 02, 2016 , ... MedPro Waste Disposal, LLC ... service. MedPro now offers its mail back service for an all-inclusive rate. MedPro ... now able to provide service to all of the clients in the country who ...
    Breaking Medicine News(10 mins):
    (Date:4/28/2016)... April 28, 2016 Oramed Pharmaceuticals Inc. ... pharmaceutical company focused on the development of oral drug delivery ... upcoming PIONEERS 2016 conference, presented by Joseph Gunnar ... New York . Nadav Kidron , ... conference. Presentation Details:   PIONEERS ...
    (Date:4/27/2016)... -- Hologic, Inc. (Nasdaq: HOLX ) announced ... second quarter ended March 26, 2016.  GAAP diluted ... and non-GAAP diluted EPS of $0.47 increased 14.6%.  ... reported basis, and 6.3% on a constant currency ... quarter, highlighted by 14.6% growth in non-GAAP EPS," ...
    (Date:4/27/2016)... , April 27, 2016 Transparency ... "Skincare Devices Market - Global Industry Analysis, Size, Share, ... the report, the global skincare devices market was valued ... to expand at a CAGR of 10.1% from 2015 ... Browse the full Skincare Devices Market (Treatment Device ...
    Breaking Medicine Technology: