Navigation Links
Medicines Used In Antiplatelet Therapy Can Reduce Heart Attacks And Strokes

Research shows that using antiplatelet medication called clopidogrel before coronary angioplasty surgery often reduces the risk of death from cardiovascular problems like heart attacks, or strokes.// The research paper was published in the latest issue of JAMA.

Dual antiplatelet therapy following percutaneous coronary intervention using a combination of drugs such as ticlopidine or clopidogrel along with aspirin helps reduce platelet activation and thrombotic and ischemic complications. However, the optimal timing of the initiation of clopidogrel has been debated. The benefit of clopidogrel pretreatment started hours to days before PCI compared with treatment given at the time of PCI in high-risk patients with acute coronary syndromes remains incompletely defined, and current guidelines do not universally recommend pretreatment.

Researchers from Harvard Medical School, Boston, had conducted a study to determine if clopidogrel pretreatment hours to days before PCI is superior to clopidogrel treatment initiated at the time of PCI in preventing major adverse cardiovascular events in patients undergoing PCI after initial pharmacological therapy for ST-segment elevation myocardial infarction.

. The study included an analysis of 1,863 patients undergoing PCI after mandated angiography for STEMI. Patients received aspirin and were randomized to receive either clopidogrel (300 mg loading dose [a comparatively large dose given at the beginning of treatment to start getting the effect of a drug more quickly], then 75 mg once daily) or placebo initiated with fibrinolysis and given until coronary angiography, which was performed 2 to 8 days after initiation of the study drug.

The researchers found that pretreatment with clopidogrel significantly reduced by 46 percent the odds of cardiovascular death, heart attack, or stroke following PCI (34 events [3.6 percent] vs. 58 events [6.2 percent].

Pretreatment with clopidogrel also reduced the odds by 38 percent of heart attack or stroke prior to PCI (37 [4.0 percent] vs. 58 [6.2 percent]. Overall, pretreatment with clopidogrel resulted in a 41 percent reduction in the odds of cardiovascular death, heart attack, or stroke from randomization through 30 days.

Source: Newswise
'"/>




Related medicine news :

1. Medicines on the move
2. Advent of New, More Effective and Personalized Medicines
3. Be Wary Of Heavy Metal Poisoning From Ayurvedic Medicines
4. Metal In Medicines Can Fight Diseases Effectively
5. Heart Patients More At Risk Get Fewer Medicines
6. Export Of Ayurvedic Medicines Affected Due To High Heavy Metal Content
7. Herbal Medicines with Animal, Human Body Parts! - Swami Ramdev Accused
8. Syrupy Medicines Increase the Risk of Tooth Decay
9. Anticholinergic Medicines Result In Cognitive Impairment
10. Wake Up Call: U.N Takes Stock to Curb Fake Medicines Racket
11. Health Minister Promises Strict Quality Control On Herbal Medicines
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/11/2016)... ... February 11, 2016 , ... Dr. Sadati’s recent ... cosmetic procedures. Along with performing procedures, the magazine also highlights that Dr. Sadati ... procedures. One of the most common procedures he performs is his natural facelift. ...
(Date:2/11/2016)... ... February 11, 2016 , ... The president released a FY 2017 ... but would shift more of the cost burden to military beneficiaries. , MOAA’s ... in the defense budget as including limited quantifiable benefit fixes mixed with numerous beneficiary ...
(Date:2/11/2016)... ... February 11, 2016 , ... ... women’s health, is pleased to announce the promotions of Allison Kelly to executive ... Steve Catone to executive vice president of North American capital sales, and Wendy ...
(Date:2/11/2016)... ... February 11, 2016 , ... The Commission ... for the Board of Commissioners. Individuals interested in volunteer board service are encouraged ... of clinical practice settings and across allied health to contribute to its mission ...
(Date:2/11/2016)... FL (PRWEB) , ... February 11, 2016 , ... ... the commencement of a master charity program created to assist the people of ... days, working closely with nonprofit organizations and community leaders. Their hope is to ...
Breaking Medicine News(10 mins):
(Date:2/11/2016)... Feb. 11, 2016 Laboratory glassware ... in laboratories. These may range from microscope slides to ... is made from borosilicate glass because of its low ... the other hand, started gaining popularity over the past ... to replace glass with plastic in several applications due ...
(Date:2/11/2016)... Calif. , Feb. 11, 2016  Walgreens has ... across 39 states and Washington, D.C. ... a move that was commended by shareholder advocacy organization As ... at As You Sow. "Many people hold on to unneeded ... which can have tragic consequences." --> Conrad ...
(Date:2/11/2016)... 11, 2016   Health 2.0 , the premiere ... technologies, announced today " 10 Year Global Retrospective ", ... over the past ten years.   ... Health 2.0 has served as the preeminent thought-leader in ... thousands of technologies, companies, innovators, and patient-activists through an ...
Breaking Medicine Technology: