Navigation Links
Medicines Used In Antiplatelet Therapy Can Reduce Heart Attacks And Strokes

Research shows that using antiplatelet medication called clopidogrel before coronary angioplasty surgery often reduces the risk of death from cardiovascular problems like heart attacks, or strokes.// The research paper was published in the latest issue of JAMA.

Dual antiplatelet therapy following percutaneous coronary intervention using a combination of drugs such as ticlopidine or clopidogrel along with aspirin helps reduce platelet activation and thrombotic and ischemic complications. However, the optimal timing of the initiation of clopidogrel has been debated. The benefit of clopidogrel pretreatment started hours to days before PCI compared with treatment given at the time of PCI in high-risk patients with acute coronary syndromes remains incompletely defined, and current guidelines do not universally recommend pretreatment.

Researchers from Harvard Medical School, Boston, had conducted a study to determine if clopidogrel pretreatment hours to days before PCI is superior to clopidogrel treatment initiated at the time of PCI in preventing major adverse cardiovascular events in patients undergoing PCI after initial pharmacological therapy for ST-segment elevation myocardial infarction.

. The study included an analysis of 1,863 patients undergoing PCI after mandated angiography for STEMI. Patients received aspirin and were randomized to receive either clopidogrel (300 mg loading dose [a comparatively large dose given at the beginning of treatment to start getting the effect of a drug more quickly], then 75 mg once daily) or placebo initiated with fibrinolysis and given until coronary angiography, which was performed 2 to 8 days after initiation of the study drug.

The researchers found that pretreatment with clopidogrel significantly reduced by 46 percent the odds of cardiovascular death, heart attack, or stroke following PCI (34 events [3.6 percent] vs. 58 events [6.2 percent].

Pretreatment with clopidogrel also reduced the odds by 38 percent of heart attack or stroke prior to PCI (37 [4.0 percent] vs. 58 [6.2 percent]. Overall, pretreatment with clopidogrel resulted in a 41 percent reduction in the odds of cardiovascular death, heart attack, or stroke from randomization through 30 days.

Source: Newswise
'"/>




Related medicine news :

1. Medicines on the move
2. Advent of New, More Effective and Personalized Medicines
3. Be Wary Of Heavy Metal Poisoning From Ayurvedic Medicines
4. Metal In Medicines Can Fight Diseases Effectively
5. Heart Patients More At Risk Get Fewer Medicines
6. Export Of Ayurvedic Medicines Affected Due To High Heavy Metal Content
7. Herbal Medicines with Animal, Human Body Parts! - Swami Ramdev Accused
8. Syrupy Medicines Increase the Risk of Tooth Decay
9. Anticholinergic Medicines Result In Cognitive Impairment
10. Wake Up Call: U.N Takes Stock to Curb Fake Medicines Racket
11. Health Minister Promises Strict Quality Control On Herbal Medicines
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/30/2016)... ... April 30, 2016 , ... Orlando-based Maximized Living has ... go for gold in Rio. Under the care of Maximized Living doctors at ... In an unprecedented showing, Maximized Living is sending the largest contingent of elite chiropractors ...
(Date:4/29/2016)... ... April 29, 2016 , ... Memorial ... for Graduate Medical Education (ACGME) that it has received accreditation for its residency ... of three residency programs that Memorial is currently pursuing, including Pediatrics and Internal ...
(Date:4/29/2016)... ... April 29, 2016 , ... Dr. Bernie Siegel, ... "LOVE, MEDICINE and MIRACLES") addresses touchy topics related to Death live on ... Dr. Bernie Siegel, author of a plethora of essential books-to-read for physicians ...
(Date:4/29/2016)... ... ... Spine Team Texas, a comprehensive spine physician group specializing in the treatment of ... invited to be a featured speaker at the Texas Society of the American College ... , Dr. R. Scott McPherson, a physical medicine and rehabilitation specialist, will speak ...
(Date:4/29/2016)... ... ... the deadliest type of skin cancer. Although only about 1 percent of skin cancer cases ... 10,000 people are expected to die of melanoma this year. The risk increases with age, ... most commonly diagnosed cancers in young women. A recent breakthrough in genetic studies may give ...
Breaking Medicine News(10 mins):
(Date:4/29/2016)... April 29, 2016 Glycotope GmbH, ... today announces the appointment of Dr. Alfredo Zurlo ... is an oncologist with many years clinical experience and ... industries. His last role was at Mologen AG where ... Executive Board. Previously Dr. Zurlo held various positions at ...
(Date:4/28/2016)...  While Abbott,s announced purchase of St. Jude ... and stent business, healthcare research firm Kalorama Information ... into patient monitoring.  Kalorama said that patient monitoring ... with double-digit growth expected the next 5 years, ... Patient Monitoring . Abbott Laboratories agreed to ...
(Date:4/28/2016)... 2016 Dr. ... und Stephen Schmidt werden ... ArisGlobal®, ein führender Anbieter cloudbasierter Softwarelösungen für ... dass neue Führungskräfte zum Team Sicherheit und ... vielfältige Erfahrungen mitbringen.  Dies wird die Geschäftseinheit ...
Breaking Medicine Technology: