Navigation Links
Medication Errors Affect Leukemia Treatment In Children

Research published in the September 15, 2006 issue of CANCER, a peer-reviewed journal of the American Cancer Society, says that around one in five children// does not receive the correct chemotherapy treatment for acute lymphoblastic leukemia (ALL). And the main reason for this is medication errors. The study says that more than 10 percent of chemotherapeutic medications were given incorrectly to outpatients. In some patients these errors caused dose related complications.

In the United States medical errors cause up to 98,000 hospital deaths per year – more deaths than by motor vehicle accidents and breast cancer combined. Medication errors are attributable to almost 7,000 inpatient deaths. Medication errors in the outpatient setting are thought to be some of the most common medical errors, but they are not well-studied, particularly in children. These mistakes can occur in prescribing by physicians, during interpretation and processing by pharmacists, and when administered by patients or their caregivers. Most mistakes among outpatients are caught before drugs are given to patients, and because most drugs have wide safety ranges, most errors are benign. Children with cancer, however, receive extremely toxic drugs with narrow safe dose ranges and must be prescribed according to specific, sometimes complex, protocols.

Led by James A. Taylor, M.D. of the University of Washington and Children's Hospital and Regional Medical Center in Seattle, researchers studied the rate and types of medications errors that occur in children receiving outpatient chemotherapy regimen for ALL. The authors reviewed the administration of drugs and the medications prescribed and dispensed to 69 enrolled patients.

One or more errors were identified in 17 of 172 (9.9 percent) chemotherapeutic medications and impacted 13 of 69 (19 percent) pediatric patients. Of the 17 errors, 12 were attributed to how the medications were administered to the patient, and 5 were attributed to prescribing errors – that is, incorrect dosages. There were no dispensing errors by a pharmacy.

Though there was little clinical impact of the errors in 9 of the 13 patients, errors in 4 children were potentially clinically significant. Three patients failed to receive medications at the appropriate time, increasing the risk of relapse. One patient received an overdose of medication and, consequently, was at greater risk for life-threatening infection.

This study identified a 10 percent error rate in outpatient chemotherapy regimens for children with ALL. "It is possible that the efficacy of treatment regimens is reduced or toxicity increased because not all children are receiving the chemotherapeutic agents as indicated," said Dr. Taylor. Moreover, the authors recommended, "in designing new [chemotherapy] protocols, a balance needs to be struck between the precision of dosing regimens and simplification so that medication errors are minimized."

Source: Eurekalert
'"/>




Related medicine news :

1. What happens when Medications go wrong?
2. Medications to Prevent Relapse to Cocaine Use
3. More Elderly Take Inappropriate and Harmful Medications
4. Medications for depression
5. Medications linked to xerostomia and caries
6. Medication recuperates fat distribution in diabetes
7. Pharmacist’s Role in Medication Error
8. The Downside of Asthma Medication
9. Reducing Medication Errors
10. Oral Medication Effective In Combating Eye Infection
11. New Medication May Decrease The Frequency Of Angina Attacks
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/30/2016)... Bay, Jamaica (PRWEB) , ... April 30, 2016 ... ... University, and Duane Boise, President and CEO of EMED, today signed a multifaceted ... Jamaica. , EMED and the Northern Caribbean University Department of Natural and Applied ...
(Date:4/29/2016)... ... April 30, 2016 , ... Mercy College is expanding its Graduate Business Programs ... be expanding due to high demand: Master of Business Administration (MBA), Master of Organizational ... , School of Business Graduate Program Chair Dr. Ray Manganelli said: “We ...
(Date:4/29/2016)... ... April 29, 2016 , ... Our bodies are bombarded daily ... confront and deal with these stressors is to adopt a more healthful diet, but ... you. Risa Groux, a certified Holistic Nutritionist and the creator of the Newport Beach ...
(Date:4/29/2016)... ... 2016 , ... Conditions were ideal for Global Lyme Alliance’s (GLA) 2nd annual ... skies, a light breeze and temperatures in the 60s. Over 400 runners, walkers and ... Walk and 1-mile walk were held to increase awareness about Lyme disease and ...
(Date:4/29/2016)... City, Missouri (PRWEB) , ... April 29, 2016 , ... ... traditional crutches which put pressure on the armpits, the M+D Crutch evenly distributes body ... strain on their wrists and hands when using the crutches than with other crutches. ...
Breaking Medicine News(10 mins):
(Date:4/28/2016)... , April 28, 2016  Marking its ... accessible breast and ovarian cancer risk test, ... analyzing 30 genes that highly impact the most ... Available today, the Color Test analyzes hereditary cancer ... stomach, and uterine cancers. The Color Test is ...
(Date:4/28/2016)... -- Dr. Vivek Ahuja , ... Ste phen Schmidt Join ... cloud-based software solutions for life sciences, today announced key new leaders ... of insight to a growing business.  This will bolster the company,s ... Phillips joined ArisGlobal in the position of Vice President - ...
(Date:4/28/2016)... , April 28, 2016 ... Review, H1 2016" is a report that provides ... helps strengthen R&D pipelines by identifying new targets ... Company Profiles discussed in this H1 ... Farmaceutiche Riunite Srl, AbbVie Inc., Abiogen Pharma S.p.A., ...
Breaking Medicine Technology: