UT Southwestern Medical Center is among 10 institutions selected to oversee innovative clinical trials designed to test life-saving interventions for critical trauma// and sudden cardiac arrest.

The National Institutes of Health has joined with other U.S. and Canadian agencies to fund the $50 million Resuscitation Outcomes Consortium (ROC) and establish federal resuscitation research centers in 10 North American regions.

The centers are expected to enroll as many as 20,000 total patients (15,000 with cardiac arrest and 5,000 with major trauma) over the next two to three years. The Dallas Center for Resuscitation Research is coordinated through UT Southwestern.

This summer, in cooperation with dozens of Dallas-area receiving hospitals, paramedics and emergency medical technicians in the BioTel System will begin administering the new interventions on-site or in the ambulance. BioTel, a coalition of emergency medicine providers serving more than a dozen Dallas area cities, receives medical oversight from UT Southwestern's emergency medicine program.

Dr. Ahamed Idris, professor of emergency medicine and a pioneer in resuscitation research and cardiopulmonary resuscitation (CPR), is the principal investigator for the Dallas Center for Resuscitation Research.

"This NIH designation not only is a great honor that places the Dallas area on the cutting-edge of life-saving research," said Dr. Idris, "but it also will immediately benefit our citizens because of the additional support, training, equipment and focus that this federal initiative will bring to the Dallas area."

In the study, trauma patients with signs of blood loss or severe brain injury will receive one of three saline solutions: standard saline, high-concentration saline, or high-concentration saline with dextran, a circulation-enhancing substance. The two concentrated saline solutions take advantage of the body's own fluids to help rapidly r
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