Navigation Links
Mechanism of Stem Cell Regulation Identified

According to the Professor Jonas Frisén who is at the Karolinska Institutet they have found ways to control the rate at which new cells are being produced// by individual intestinal stem cell. The result of the study was published in the journal Cell. The research feels that this might help in the development of new drugs for diseases such as neurological disorders and anemia. In most organs of the body, old cells are continually being replaced by new. If too many new cells are produced, however, it can lead to overgrowth and tumor formation. Too few cells, on the other hand, can result in organ degeneration. It is therefore crucial that exactly the right number of cells is produced.

As many serious disorders cause a reduction in the production of new cells, scientists are keen to develop drugs that stimulate the process, which in turn could help the body to cure itself. It has long been known that the new cells are often formed by immature cells known as stem cells, but the mechanism regulating the number of new cells produced has remained something of a mystery. However, in a new study to be published by Cell stem-cell researcher Jonas Frisén has succeeded in showing how the body's own stem cells do just this. Working alongside an American group of researchers, Professor Frisén and his team have identified a signal transduction process that regulates the degree of stem-cell division. "Understanding how cell production is regulated increases our chances of producing drugs able to stimulate the endogenous production of new cells," says Professor Frisén.

He hopes that the new findings can be used to develop drugs that stimulate, for example, the formation of new nerve cells to treat conditions such as stroke and Parkinson's and skin cells to facilitate the healing of wounds. Professor Frisén is best known for his research on cerebral stem cells; the present study, however, has been carried out on stem cells in the intestine, one of the organs in t he body with the highest rates of cell renewal. ‘We also know that blood, brain and skin stem cells express the genes that we now know to be important in the intestine,’ he says. ‘This suggests that the cell production mechanism can be the same for these stem cells too.’ The next step for Professor Frisén and his group is therefore to study how blood and skin stem cells go about producing new cells.

Source: Euekalert

Related medicine news :

1. Scientists Unveil Mechanism Behind Resistance to Severe Malaria
2. New Gene Silencing Mechanism To Prevent Cancer
3. Molecular Mechanism Of HIV Infecting The Healthy Cells Discovered.
4. Self-defense Mechanism of food borne bugs found
5. Specific Immune Mechanism against DNA viruses
6. A New Focus For The Mechanism Of Nerve Growth
7. Cancer-Killing Viruses Employ Multiple Mechanisms
8. Regulatory Mechanism for Tumor Suppressor Protein Identified
9. Study Identifies Mechanism Which May Help Tamoxifen Work Better
10. Genetic Mechanism Helps Explain Chronic Pain Disorders
11. New Mechanism for Nutrient Uptake Discovered
Post Your Comments:

(Date:11/27/2015)... ... November 27, 2015 , ... A team of Swiss doctors has released a ... Mesothelioma has just posted the findings on the website. Click here to read ... of 136 mesothelioma patients who were treated with chemotherapy followed by EPP surgery. Among ...
(Date:11/27/2015)... ... November 27, 2015 , ... ... 27th edition of USA Today in Atlanta, Dallas, New York, Minneapolis, South Florida, ... The digital component is distributed nationally, through a vast social media strategy and ...
(Date:11/27/2015)... ... November 27, 2015 , ... Intellitec Solutions announced ... User Group (MSDSLUG). Recognized as Microsoft’s official group for end users of Dynamics ... software users, partners, industry experts and representatives. Intellitec Solutions’ membership status demonstrates their ...
(Date:11/27/2015)... ... November 27, 2015 , ... CBD College ... Allied Health Education Programs (CAAHEP) awarded accreditation to its Diagnostic Medical Sonography program. CBD ... colleges, as only one of twelve colleges and universities in the state of California ...
(Date:11/27/2015)... ... 27, 2015 , ... Indosoft Inc., developer and distributor of ... 11 LTS (Long Term Support) into its Q-Suite 5.10 product line. , Making ... with a version of Asterisk that will receive not only security fixes, but ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... , November 26, 2015 ... A new combination approach blends immunotherapy with Bremachlorin-photodynamic therapy ... new combination approach blends immunotherapy with Bremachlorin-photodynamic therapy for ... new combination approach blends immunotherapy with Bremachlorin-photodynamic therapy for ... has found that immunotherapy can be efficiently ...
(Date:11/26/2015)... 2015 Research and Markets ( ... "2016 Future Horizons and Growth Strategies in the ... Country Segment Forecasts, Competitive Intelligence, Emerging Opportunities" ... --> --> This new 247-page ... therapeutic drug monitoring market, including emerging tests, technologies, ...
(Date:11/26/2015)... DUBLIN , Nov. 26, 2015 Research ... of the "Advanced Wound Care Market by Type ... Ulcers), End User (In-Patient Facility, Out-Patient Facility), and Geography ... offering. --> --> ... the description, definition and forecast of the global advanced ...
Breaking Medicine Technology: