Navigation Links
Mechanism of Stem Cell Regulation Identified

According to the Professor Jonas Frisén who is at the Karolinska Institutet they have found ways to control the rate at which new cells are being produced// by individual intestinal stem cell. The result of the study was published in the journal Cell. The research feels that this might help in the development of new drugs for diseases such as neurological disorders and anemia. In most organs of the body, old cells are continually being replaced by new. If too many new cells are produced, however, it can lead to overgrowth and tumor formation. Too few cells, on the other hand, can result in organ degeneration. It is therefore crucial that exactly the right number of cells is produced.

As many serious disorders cause a reduction in the production of new cells, scientists are keen to develop drugs that stimulate the process, which in turn could help the body to cure itself. It has long been known that the new cells are often formed by immature cells known as stem cells, but the mechanism regulating the number of new cells produced has remained something of a mystery. However, in a new study to be published by Cell stem-cell researcher Jonas Frisén has succeeded in showing how the body's own stem cells do just this. Working alongside an American group of researchers, Professor Frisén and his team have identified a signal transduction process that regulates the degree of stem-cell division. "Understanding how cell production is regulated increases our chances of producing drugs able to stimulate the endogenous production of new cells," says Professor Frisén.

He hopes that the new findings can be used to develop drugs that stimulate, for example, the formation of new nerve cells to treat conditions such as stroke and Parkinson's and skin cells to facilitate the healing of wounds. Professor Frisén is best known for his research on cerebral stem cells; the present study, however, has been carried out on stem cells in the intestine, one of the organs in t he body with the highest rates of cell renewal. ‘We also know that blood, brain and skin stem cells express the genes that we now know to be important in the intestine,’ he says. ‘This suggests that the cell production mechanism can be the same for these stem cells too.’ The next step for Professor Frisén and his group is therefore to study how blood and skin stem cells go about producing new cells.

Source: Euekalert
'"/>




Related medicine news :

1. Scientists Unveil Mechanism Behind Resistance to Severe Malaria
2. New Gene Silencing Mechanism To Prevent Cancer
3. Molecular Mechanism Of HIV Infecting The Healthy Cells Discovered.
4. Self-defense Mechanism of food borne bugs found
5. Specific Immune Mechanism against DNA viruses
6. A New Focus For The Mechanism Of Nerve Growth
7. Cancer-Killing Viruses Employ Multiple Mechanisms
8. Regulatory Mechanism for Tumor Suppressor Protein Identified
9. Study Identifies Mechanism Which May Help Tamoxifen Work Better
10. Genetic Mechanism Helps Explain Chronic Pain Disorders
11. New Mechanism for Nutrient Uptake Discovered
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/24/2017)... ... May 24, 2017 , ... NucleusHealth ™, advancing clinical ... U.S. Food and Drug Administration (FDA) 510(k) clearance for its ... platform for medical image management. At the core is patented streaming technology that ...
(Date:5/24/2017)... Cortland, OH (PRWEB) , ... May 24, 2017 , ... ... in Cortland, OH, can now meet with Dr. Joseph Bedich for a consultation, ... smiles while simultaneously improving their oral health and functionality. , Dr. Bedich ...
(Date:5/24/2017)... ... May 24, 2017 , ... Dr. Curry Leavitt, a noted ... Periodontal Practice) continuing education (CE) series. As a compassionate and dedicated clinician, Dr. ... attending numerous CE courses each year. His recent course, Course II of HP3, ...
(Date:5/24/2017)... ... May 24, 2017 , ... Accordant ... its solutions portfolio. ExtraHop delivers an analytics-first approach, layered with machine learning, that ... from the datacenter to the cloud to the edge. Through the new partnership, ...
(Date:5/24/2017)... ... 2017 , ... Rob Lowe is a sought after actor, and also serves ... the public important topics from all aspects of life, and a new segment is ... feet and ankles. , Podiatry is essential to people’s overall well-being, and if viewers ...
Breaking Medicine News(10 mins):
(Date:5/10/2017)... 10, 2017 Radiology has become the number ... have also spiraled to the number one ranking as ... than ever before as the most complete and reliable ... with lower back pain an MRI may confirm a ... pain, resulting in entirely different treatment protocols.  In these ...
(Date:5/9/2017)... , May 9, 2017  Oramed Pharmaceuticals Inc. ... a clinical-stage pharmaceutical company focused on the development ... the Canadian Intellectual Property Office has granted Oramed ... Administration of Exenatide". The patent covers Oramed,s invention ... GLP-1 is an incretin hormone that stimulates ...
(Date:5/6/2017)... --  Provista , a proven leader in the supply chain ... Jim Cunniff as the company,s new president and ... to Provista, including most recently serving as the president and ... . He assumed his new role with Provista on May ... Provista," says Jody Hatcher , president, Sourcing and Collaboration ...
Breaking Medicine Technology: