Navigation Links
Mechanism of Stem Cell Regulation Identified

According to the Professor Jonas Frisén who is at the Karolinska Institutet they have found ways to control the rate at which new cells are being produced// by individual intestinal stem cell. The result of the study was published in the journal Cell. The research feels that this might help in the development of new drugs for diseases such as neurological disorders and anemia. In most organs of the body, old cells are continually being replaced by new. If too many new cells are produced, however, it can lead to overgrowth and tumor formation. Too few cells, on the other hand, can result in organ degeneration. It is therefore crucial that exactly the right number of cells is produced.

As many serious disorders cause a reduction in the production of new cells, scientists are keen to develop drugs that stimulate the process, which in turn could help the body to cure itself. It has long been known that the new cells are often formed by immature cells known as stem cells, but the mechanism regulating the number of new cells produced has remained something of a mystery. However, in a new study to be published by Cell stem-cell researcher Jonas Frisén has succeeded in showing how the body's own stem cells do just this. Working alongside an American group of researchers, Professor Frisén and his team have identified a signal transduction process that regulates the degree of stem-cell division. "Understanding how cell production is regulated increases our chances of producing drugs able to stimulate the endogenous production of new cells," says Professor Frisén.

He hopes that the new findings can be used to develop drugs that stimulate, for example, the formation of new nerve cells to treat conditions such as stroke and Parkinson's and skin cells to facilitate the healing of wounds. Professor Frisén is best known for his research on cerebral stem cells; the present study, however, has been carried out on stem cells in the intestine, one of the organs in t he body with the highest rates of cell renewal. ‘We also know that blood, brain and skin stem cells express the genes that we now know to be important in the intestine,’ he says. ‘This suggests that the cell production mechanism can be the same for these stem cells too.’ The next step for Professor Frisén and his group is therefore to study how blood and skin stem cells go about producing new cells.

Source: Euekalert
'"/>




Related medicine news :

1. Scientists Unveil Mechanism Behind Resistance to Severe Malaria
2. New Gene Silencing Mechanism To Prevent Cancer
3. Molecular Mechanism Of HIV Infecting The Healthy Cells Discovered.
4. Self-defense Mechanism of food borne bugs found
5. Specific Immune Mechanism against DNA viruses
6. A New Focus For The Mechanism Of Nerve Growth
7. Cancer-Killing Viruses Employ Multiple Mechanisms
8. Regulatory Mechanism for Tumor Suppressor Protein Identified
9. Study Identifies Mechanism Which May Help Tamoxifen Work Better
10. Genetic Mechanism Helps Explain Chronic Pain Disorders
11. New Mechanism for Nutrient Uptake Discovered
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/5/2016)... Austin, TX (PRWEB) , ... December 05, 2016 ... ... Center for Facial Plastic Surgery, is excited to announce the arrival of the ... hybrid fractional laser, with the ability to use tunable non-ablative and ablative wavelengths ...
(Date:12/5/2016)... ... , ... Researchers at Johns Hopkins All Children’s Hospital want to learn more ... course of three years, researchers will study concussions and changes in brain function by ... special sensors, will track the location and force of the hit. The sensors store ...
(Date:12/5/2016)... Nashville, Tennessee (PRWEB) , ... ... ... leader in strategic interoperability, today announced that the company will provide alerting ... platform. CIHIE has been recently awarded $1.7 million in federal funds as ...
(Date:12/5/2016)... ... ... Sideline Products is a Southern York County Pennsylvania-based premier designer and manufacturer founded ... Smaller saddles can pinch and irritate the horse creating safety issues and limiting comfort ... saddle so it does not impact the comfort or performance of the horse. Further, ...
(Date:12/5/2016)... ... 05, 2016 , ... The legislation – S2718A/A2116A ... a licensed physical therapist, to render care for certain patients. In most cases, ... a licensed physical therapist (PT) and throughout the treatment cycle is supported by ...
Breaking Medicine News(10 mins):
(Date:12/5/2016)... LAS VEGAS , Dec. 5, 2016  BD ... a leading global medical technology company, will demonstrate an ... BD medication management technologies, including the company,s leading Pyxis™ ... of Health-System Pharmacists (ASHP) 2016 Midyear Meeting being ... Dec. 4-8. While national data show that ...
(Date:12/5/2016)... Dec 5, 2016 Research and Markets has announced ... Global Forecast to 2021" report to their offering. ... , , The ... billion by 2021, at a CAGR of 5.3% from 2016 to 2021. ... of obesity cases, increasing government spending on healthcare, and rising income levels ...
(Date:12/5/2016)... Israel , December 5, 2016 ... identifying, in-licensing and developing promising therapeutic candidates, presents positive Phase ... BL-8040, the Company,s leading oncology platform at the ongoing 58th ... San Diego, California . ... , , ...
Breaking Medicine Technology: