Navigation Links
Measuring disseminated cancer cells in bone marrow - valuable tool for detecting early breast cancer metastasis

Stephan Braun and colleagues have reported in the New England Journal of Medicine, that the detection of disseminated tumor cells in bone marrow samples is a more reliable determinant of metastasis and patient survival. //

The disease progression is measured by taking biopsy samples from breast cancer patients and the level of lymph node metastases is measured to determine the disease prognosis. But research results as shown that 30% of patients with lymph node negative status still develop metastatic disease. A new approach to overcome this has been found in which the detection of micrometases in bone marrow is detected which can be a better clinical tool for early detection of disease metastasis.

Breast tumor cells frequently bypass the lymph nodes and disseminate directly through the blood to distant organs. This Hematogenous dissemination of cancer cells has been shown to be an early event in tumor progression. Analysis of data from 9 studies involving 4,703 patients with stage I, II or III breast cancer, the authors evaluated the association between detection of bone marrow micrometastases and patient outcome over a 10 year period.

The study compared the effects of different factors, such as tumor size, grade, bone marrow metastasis, lymph node metastasis and hormone receptor expression , and revealed that the presence of micrometases in bone marrow were the best predictors of outcome within the first 5 years after diagnosis. Bone marrow micrometastases were detected in over 30% of patients and these patients were found to develop larger tumors with a higher histological grade that more frequently metastasized to other organs.

Patients with bone marrow micrometastases were more likely to die of the disease, even among patients that received adjuvant therapy. In patients with very small tumors without lymph node metastases, and who therefore did not receive adjuvant therapy, the presence of bone marrow micrometastase
'"/>




Page: 1 2

Related medicine news :

1. Measuring Death Risk in COPD Patients
2. Measuring Exercise Capacity To Predict Heart Disease
3. A Novel Method For Measuring Interstitial Fluid Pressure In Cancer Tissues
4. Measuring Urinary Protein Helps In Detecting Recurrent Bladder Cancer
5. New Method For Measuring Dyskinesia In Parkinsons Being Developed
6. Measuring the Quantity of Information Passed on From the Eye to the Brain
7. Measuring Calcium Intake Help to Identify Osteoporosis in Prostate Cancer Patient
8. Vitamin B12 can help in detecting cancers
9. Want skin cancer? Please have a cigarette
10. New hope for cancer victims – will vaccine cure the deadly bug
11. Clintons new problem - Is the outgoing American president suffering from skin cancer?
Post Your Comments:
(Date:3/1/2015)... 2015 Researchers say working around asbestos-containing ... sheet metal workers contract malignant mesothelioma. Surviving Mesothelioma has ... its website. Click here to read it now. ... and Training monitored 17,345 sheet metal workers from 1986 ... them died of mesothelioma or another asbestos-related disease ...
(Date:3/1/2015)... (PRWEB) March 01, 2015 ERISAPros ... King and Carolyn Roddy to the professional staff of ... Compliance, graduated from The Ohio State University-Mortiz College of ... years of experience working with several Fortune 500 companies ... the area of corporate benefits. Her experiences range from ...
(Date:2/28/2015)... In recent years Medical Marijuana has continuously ... as a way for them to expand their patient base ... medicine. Since the FDA still lists Cannabis as a Schedule ... licensed physicians that can help guide them when recommending ... in Santa Cruz, CA is a leader in the ...
(Date:2/28/2015)... 2015 The Heart Fit Clinic started ... of the machine. The Heart Fit Clinic is also ... a franchise model. The goal is to scale the ... disease. To buy External Counterpulsation machines can ... individuals through this process and achieve the desired results. ...
(Date:2/28/2015)... Indosoft Inc , developers of ... are pleased to announce the development of Q-Suite 5.9. ... versions of Q-Suite, this new version will include enhancements ... new features to the leading edge call center software. ... will add features to enhance security and protection. Administrators ...
Breaking Medicine News(10 mins):Health News:New Study Finds Indirect Asbestos Exposure Can Raise Mesothelioma Risk for Sheet Metal Workers, According to Surviving Mesothelioma 2Health News:ERISAPros Recruits Evelyn King, J.D. and Carolyn Roddy, J.D. to its Professional Staff 2Health News:Reputable Cannabis Doctor In Santa Cruz and Monterey Joins the Medical Cannabis Network 2Health News:Clinicians Can Now Purchase External Counterpulsation with Heart Fit Clinic 2Health News:Indosoft Proudly Announces Q-Suite 5.9 Call Center Software for Asterisk 2
... immune system, says a study conducted by Spanish researchers . ... C, B-complex vitamins and has good doses of minerals like ... known that potatoes are good for bowel health. ... particularly if eaten cold or in a salad, the researchers ...
... to the coastal Spanish town of Altea to get Oslo-funded ... to fractured bones. ,"In Norway it is cold ... why they are better off here," the tanned head of ... ,The rehabilitation centre was set up and is run by ...
... are an indicator of an industry's health, then the turnout ... and spirits fair, confirms the sector is doing nicely, if ... this year's show, a two-yearly event in Bordeaux, a three ... for Vinexpo by the London-based International Wine and Spirit Record ...
... with a life-threatening illness, a young Indian American is hard ... 10 as very few South Asians are listed in the ... Chakravarthy was diagnosed with a disease known as Acute Myelogenous ... bone marrow, the South Asian community has come together nationwide ...
... up with a partner in Harley Street - a ... are frequented by celebrities - and is introducing ... into tie-up based on her franchise system with the ... Ayurveda on Harley Street is indicative of the increasing ...
... Fey has launched an entirely new kind of healthcare ... culture of prevention throughout America and the world -- ... to one that encourages people to take early steps ... ,This message appears this week in a full-page ad in ...
Cached Medicine News:Health News:Intake of Potatoes Boosts the Immune System 2Health News:Norwegians Take in the Sun in Spain on Doctors' Orders 2Health News:World Wine Sales Brisk, but French Producers Hungover 2Health News:World Wine Sales Brisk, but French Producers Hungover 3Health News:South Asians Seek Bone Marrow for Young Indian American 2Health News:Shahnaz Hussain Takes Ayurveda to London's Harley Street 2Health News:U.S. Preventive Medicine(R) Encourages the International Community to Embrace Prevention 2
(Date:2/27/2015)... Feb. 27, 2015 Securities lawyers at ... Salix Pharmaceuticals, Ltd. (NASDAQ: SLXP ) in ... Concerned SLXP investors are encouraged to contact attorney Hamilton ... The investigation focuses upon the shareholder value of the ... would receive only $158.00 per share in cash. At ...
(Date:2/27/2015)... -- Report Details   Translational ... progress, and predicted revenues ,Where is the market for ... prospects for this market and related technologies? Visiongain,s brand ... to 2025, discussing data, opportunities and prospects. ... medicine : cell-based therapies that aim to restore function ...
(Date:2/27/2015)... , Feb. 27, 2015  Organovo Holdings, Inc. ... focused on delivering breakthrough 3D bioprinting technology, announced ... Chief Executive Officer, will present live at VirtualInvestorConferences.com ... you to join us for this Company update," ... on our commercial launch of the exVive3D Liver, ...
Breaking Medicine Technology:Translational Regenerative Medicine: Market Prospects 2015-2025 2Translational Regenerative Medicine: Market Prospects 2015-2025 3Translational Regenerative Medicine: Market Prospects 2015-2025 4Translational Regenerative Medicine: Market Prospects 2015-2025 5Translational Regenerative Medicine: Market Prospects 2015-2025 6Translational Regenerative Medicine: Market Prospects 2015-2025 7Translational Regenerative Medicine: Market Prospects 2015-2025 8Organovo Holdings, Inc. to Provide Corporate Update and Investor Presentation in a Live, Interactive Webcast on March 5th 2Organovo Holdings, Inc. to Provide Corporate Update and Investor Presentation in a Live, Interactive Webcast on March 5th 3Organovo Holdings, Inc. to Provide Corporate Update and Investor Presentation in a Live, Interactive Webcast on March 5th 4
... 2011 In a comparative pharmacokinetic (PK) study, ... of topiramate in development for the management of ... to twice-daily immediate-release topiramate (Topamax®*) in its extent ... food, demonstrated a slower absorption profile compared with ...
... Medical, Inc., the global leader in devices for clot removal ... the launch of the DAC® 070 Catheter. The DAC 070 ... DAC family, making it the most complete family of distal ... was the first in a new class of catheters known ...
Cached Medicine Technology:PK Study Comparing Upsher-Smith's Extended-Release Topiramate Formulation (USL255) With Topamax® Published Online In Epilepsia 2PK Study Comparing Upsher-Smith's Extended-Release Topiramate Formulation (USL255) With Topamax® Published Online In Epilepsia 3Concentric Medical Launches DAC® 070, A New Distal Access Catheter 2Concentric Medical Launches DAC® 070, A New Distal Access Catheter 3
A stable revision design with extensive sizes...
Severe revision options for the knee and hip...
The Natural-Hip combines the surgical simplicity of a straight stem with many of the best features of an anatomic stem....
The Natural-Hip combines the surgical simplicity of a straight stem with many of the best features of an anatomic stem....
Medicine Products: