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Measuring Urinary Protein Helps In Detecting Recurrent Bladder Cancer

Recurrent bladder cancer can be detected through measuring a certain protein present in the urine. Where the US is concerned, bladder cancer is reported to be the fifth most malignant, which recorded 63,210 new cases in the year 2005 //year alone, with over 13,000 deaths. The country has a total of 500,000 patients with a bladder cancer history, and the chances of its recurrence is between 50% and 90%.

There is no known procedure of monitoring this ailment which is 100% perfect. The standard approach is the cystoscopy approach. The cytologic (cell) analysis has a reputation for variability and poor sensitivity while interpreting results. A noninvasive urine test’s clinical utility was examined by the Anderson Cancer Center’s H. Barton Grossman. This is a test for the protein NMP22 which helps in detecting recurrent cancer.

The study involved 668 patients who had a history of the ailment. The urine samples were tested for the NMP22 protein before the cystoscopy. As many as 103 bladder cancer cases were identified, and 91.3% of them were identified by cystoscopy. When cystoscopy was combined with NMP22, about 99% of the malignancies were detected, thus proving the efficacy of the combination.
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