Navigation Links
Maths Theory Shows Genetic Pattern of Tumour Growth

University of California, Irvine (UCI) researchers have shown how cancer cells can alter their own genetic makeup to accelerate tumour growth by using a mathematical theory.

This is the first study to show why such alterations in the genetic makeup of cancer cells occur. It provides insight into how tumours thrive, besides offering a potential foundation for future cancer treatments.

Mathematicians Natalia Komarova, Alexander Sadovsky, and Frederic Wan focused on the phenomenon of genetic instability, a common feature of cancer in which cells mutate at an abnormally fast rate, with a view to determining what can a tumour do to optimise its own growth.

The researchers say that such mutations can cause cancer cells to proliferate or to die.

It was found that tumours grow best when cancerous cells mutate to speed up malignant transformation, and then stay that way by turning off the mutation rate.

Mathematical theory can help us understand cancer. If we know what cancer is doing, we might be able to find ways to fight it, said Komarova, Associate Professor of Mathematics at UCI.

In order to determine the patter of genetic changes that leads to the most robust tumour growth, Komarova and her colleagues used a mathematical technique called optimal control theory in which they considered a tumour with set characteristics, then changed the cell mutation variable to see under which circumstances the tumour grew best.

The mutation rate serves as the control knob. Then, we can calculate mathematically how long it takes a tumour with given parameters to reach a certain size, Komarova said.

We found that at early stages of tumour growth, instability is advantageous, and later on it becomes an impediment. This explains why many tumours exhibit a high level of instability at first, and become stable later in their development, she added.

The study has be
'"/>




Page: 1 2

Related medicine news :

1. Students With Sleep Disorder Symptoms Score Badly in Maths
2. Researchers Have Found Reason Why Boys are Better at Maths Than Girls
3. New Information On Virus Goes Against The Age-Old Theory
4. Controversial Theory Says DNA Can Be Pushed To "Dark States"
5. Study Refutes Theory on HIVs Effect on White Blood Cells
6. Theory of How HIV Attacks is Wrong: Study
7. Experimental treatment for Ebola Virus Shows promising results in mice
8. New Prostate Cancer Vaccine Shows Promise
9. Ebola Treatment Shows Promise
10. New Drug Shows Significant Improvement In HIV-related Heart Condition
11. Greek Study Shows Living In The Hills May Be Healthier
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Maths Theory Shows Genetic Pattern Tumour Growth

(Date:10/20/2014)... T.E.N., a technology and information ... that William H. Murray, renowned author and industry ... Leadership Award winner. Presented annually, the ISE® Luminary ... leader and industry practitioner for his or her ... information security industry. , Formerly with IBM, Murray ...
(Date:10/20/2014)... October 20, 2014 Zereana Jess-Huff, a 34-year-old ... Maryland 2014 on a platform to think outside the bra. ... uses her position to raise awareness about women’s other lady ... breast cancer. You say the color pink and everybody knows ... for a fact that it has not been won when ...
(Date:10/20/2014)... My Clients Plus ( http://www.MyClientsPlus.com ) today announced ... module enables easy administration and routing of follow-up items ... This application allows users such as Therapists to assign ... item to a specific client, categorize tasks the way ... for follow-ups. It's designed to enable easy access ...
(Date:10/20/2014)... Diego, CA (PRWEB) October 20, 2014 AttorneyOne.com, ... all the latest information from the FDA on Sit ... on October 10 not to purchase or use Sit and ... Sit and Slim II is promoted as weight loss product ... Sibutramine, removed from the market in 2010 for safety reasons, ...
(Date:10/20/2014)... Rockynol Retirement Community broke ground ... The $11 million project will include the latest in ... with full-service restaurant style dining. , “We are excited ... Assisted Living apartments,” said Kara Hanzie, Rockynol Executive Director ... of care and this investment is proof of our ...
Breaking Medicine News(10 mins):Health News:Bill Murray named 2014 ISE® Luminary Leadership Award Winner 2Health News:Bill Murray named 2014 ISE® Luminary Leadership Award Winner 3Health News:Bill Murray named 2014 ISE® Luminary Leadership Award Winner 4Health News:Ovarian Cancer Survivor Mrs. Maryland Urges Media to Think Outside the Bra 2Health News:Ovarian Cancer Survivor Mrs. Maryland Urges Media to Think Outside the Bra 3Health News:My Clients Plus Announces New Workflow Management Software 2Health News:FDA Advises Not to Use Sit and Slim II: AttorneyOne Monitors and Keeps Consumers Informed 2Health News:Rockynol Retirement Community Expands Assisted Living Center 2
... variations that point to spectrum disorders , TUESDAY, March ... for brain proteins that seem to be linked to ... of the most comprehensive genetic analyses of association between ... spectrum disorder] risk," said Anthony Monaco, of the Wellcome ...
... ... Detox Protocol using Far Infrared. FIR therapy is a major key for returning us back ... ... Ph.D., RIET-1, a Doctor of Integrative Medicine and an Industrial Toxicologist, has dedicated a ...
... complications, costs, , TUESDAY, March 30 (HealthDay News) -- Current ... age 45, especially for those who are overweight, but new ... 30 and 45 for everyone . , When screening ... every year to five years, the average cost per quality-adjusted ...
... lung cancer per year in Germany are due to ... in the current edition of Deutsches rzteblatt International ... and his coauthors ( Dtsch Arztebl Int 2010; ... the results of relevant studies, the recently published S1 ...
... One in three South Asian, West Asian or Arab women ... say they have trouble accessing a doctor to address ... findings, from a new study by researchers at St. Michael,s ... finds this group and immigrant women and men are at ...
... ... Misunderstandings about proper use of antibiotics have the potential to ... report in the April issue of AJIC: American Journal of Infection ... Control and Epidemiology, Inc. (APIC). esearchers from Columbia University and MixedInk ...
Cached Medicine News:Health News:Scientist, Dr Staninger, Unlocks the Mystery of Morgellons Disease 2Health News:Scientist, Dr Staninger, Unlocks the Mystery of Morgellons Disease 3Health News:Diabetes Screening Should Start Sooner 2Health News:Diabetes Screening Should Start Sooner 3Health News:Minority women least likely to gain access to a doctor, study says 2Health News:Misinformation About Antibiotics Can Travel to Large Audience Via Twitter: Study 2Health News:Misinformation About Antibiotics Can Travel to Large Audience Via Twitter: Study 3Health News:Misinformation About Antibiotics Can Travel to Large Audience Via Twitter: Study 4Health News:Misinformation About Antibiotics Can Travel to Large Audience Via Twitter: Study 5
(Date:10/20/2014)... 2014 Valeritas, Inc., a leader in simple, ... Type 2 diabetes, announced today that it has received ... award was presented October 16 th at Cardinal,s ... . The Cardinal Health Supply ... of metrics specifically targeted at the importance of developing ...
(Date:10/20/2014)...  AnaptysBio, Inc., a leader in the discovery ... appointment of Marco Londei , M.D. as ... preclinical and clinical development of AnaptysBio,s proprietary antibody ... welcome Dr. Londei to AnaptysBio,s executive leadership team," ... Executive Officer of AnaptysBio. "Dr. Londei,s extensive expertise ...
(Date:10/20/2014)... Lpath, Inc. (NASDAQ: LPTN ... official notification from the European Patent Office that ... supporting its iSONEP™ and ASONEP™ programs. ... 2087002, claims compositions of matter related to sonepcizumab, ... iSONEP and ASONEP. Sonepcizumab is an antibody that ...
Breaking Medicine Technology:Valeritas Receives 2014 Cardinal Health Supply Chain Excellence Award 2Valeritas Receives 2014 Cardinal Health Supply Chain Excellence Award 3AnaptysBio Appoints Dr. Marco Londei to Newly Created Chief Development Officer Position Clinical Immunologist to Lead AnaptysBio's Pipeline Advancement 2Lpath Granted Key European Patent Related to iSONEP and ASONEP Programs 2Lpath Granted Key European Patent Related to iSONEP and ASONEP Programs 3Lpath Granted Key European Patent Related to iSONEP and ASONEP Programs 4
Used to introduce large devices for vascular intervention....
Used to introduce balloon, closed and non-tapered end catheters and other devices for intervention....
Used to introduce balloon, closed and non-tapered end catheters or other devices for intervention....
Used to introduce balloon, electrode, closed or non-tapered end and other catheters....
Medicine Products: