Navigation Links
Mass Spectrometry to Identify Viruses

Although mass spectrometry has been used to determine the chemical composition of materials for decades it had rarely been used to identify viruses// especially in complex environmental samples.

Researchers at the Johns Hopkins Bloomberg School of Public Health successfully separated, purified and concentrated a norovirus surrogate from a clinical sample within a few hours using proteomic mass spectrometry.

Human norovirus causes gastrointestinal illness, commonly on cruise ships. Because of their mass spectrometric method they have immense potential as a tool for biodefens. The results of the study is published in the April 2006 edition of Applied and Environmental Microbiology.

In mass spectrometry is essentially a laser turns a sample into ionized particles, which are then accelerated in a vacuum toward a detector. The time lapsed prior to their being detected on a detector helps researchers determine the mass of the particles. By targeting characteristic particles, or peptides, belonging to the viral coat protein, the virus can be correctly identified by matching the results to entries in genetic databases.

In the Hopkins study, a stool sample treated with non-infectious virus-like particles, structurally similar to the norovirus was analyzed using mass spectrometry. Norovirus capsid protein was noted down to levels commonly found in clinical specimens from sick individuals.

This process is especially significant because of the fact that the norovirus cannot be cultured outside the human body.

This could be a significant step towards the use of mass spectrometry as an environmental surveillance tool in detecting pathogenic human viruses in complex environmental samples.


Page: 1

Related medicine news :

1. Magnetic Resonance Spectrometry for speedy diagnosis of Brain disorders
2. Laboratory Testing Can Identify Risk of Pre-Term Labor and Delivery
3. Identifying bacteria made amiable
4. Identifying brain lesions with impaired consciousness
5. Identifying Virus Found To Be Essential for HIV Patients
6. Identifying Those At Risk For Diabetes
7. Identifying Predictors Of Anthrax
8. Identifying The Risks Of Developing Schizophrenia
9. Identifying Irregular Heart Beats
10. Identifying Those At Risk For Diabetes
11. Identifying Heart Disease Early
Post Your Comments:

(Date:11/25/2015)... ... November 25, 2015 , ... For the first time, Vitalalert is donating half ... ” campaign. The partnership between the two groups began in 2014 with Vitalalert pledging ... , MAP International was founded in 1954 and is an international Christian-based health organization ...
(Date:11/25/2015)... ... 25, 2015 , ... On November 25, 2015, officials of Narconon Arrowhead ... the release of a new cutting edge recovery program that has been 50 years ... drug- and alcohol-addicted individuals with the purpose to free addicts from the symptoms and ...
(Date:11/25/2015)... ... 2015 , ... Smiles by Stevens is pleased to announce the ... While many patients are aware of the benefits of Botox® in the treatment of ... suffering with discomfort, soreness, and pain as a result of Jaw Tension, TMJ (temporo-mandibular ...
(Date:11/25/2015)... MI (PRWEB) , ... November 25, 2015 , ... In ... Presence Resurrection Medical Center (RMC) in Chicago, IL, UV Angel is evaluating the efficacy ... medical and surgical intensive care units (totaling 30 beds) from May 2014 through October ...
(Date:11/25/2015)... ... November 25, 2015 , ... In honor ... Periwinkle Pioneers, individuals and groups responsible for advancing care for pulmonary hypertension (PH) ... nominated by the public, will receive special recognition throughout 2016 as part of ...
Breaking Medicine News(10 mins):
(Date:11/25/2015)... plc (NYSE: AGN ) today announced that it has ... Attorney General,s Office to end the litigation under ... the Attorney General over the decision of Forest Laboratories, Inc., ... now generic version of memantine immediate release tablets.  Under the ... counterclaims against New York , and has ...
(Date:11/25/2015)... 2015 Allergan plc (NYSE: AGN ... Therapeutics, a start-up  biotechnology company focused on the ... and funded by the F-Prime Biomedical Research Initiative ... an exclusive collaboration to support the discovery and ... (ASD) and Obsessive Compulsive disorders (OCD). ...
(Date:11/25/2015)... November 25, 2015 --> ... blood glucose devices was valued at $11,171.1 million in ... CAGR of 5.7% during 2015 - 2022. The global ... increasing prevalence of diabetes. In addition, the increase in ... also contributing to the growth of the market. Furthermore, ...
Breaking Medicine Technology: