Navigation Links
Mass Spectrometry to Identify Viruses

Although mass spectrometry has been used to determine the chemical composition of materials for decades it had rarely been used to identify viruses// especially in complex environmental samples.

Researchers at the Johns Hopkins Bloomberg School of Public Health successfully separated, purified and concentrated a norovirus surrogate from a clinical sample within a few hours using proteomic mass spectrometry.

Human norovirus causes gastrointestinal illness, commonly on cruise ships. Because of their mass spectrometric method they have immense potential as a tool for biodefens. The results of the study is published in the April 2006 edition of Applied and Environmental Microbiology.

In mass spectrometry is essentially a laser turns a sample into ionized particles, which are then accelerated in a vacuum toward a detector. The time lapsed prior to their being detected on a detector helps researchers determine the mass of the particles. By targeting characteristic particles, or peptides, belonging to the viral coat protein, the virus can be correctly identified by matching the results to entries in genetic databases.

In the Hopkins study, a stool sample treated with non-infectious virus-like particles, structurally similar to the norovirus was analyzed using mass spectrometry. Norovirus capsid protein was noted down to levels commonly found in clinical specimens from sick individuals.

This process is especially significant because of the fact that the norovirus cannot be cultured outside the human body.

This could be a significant step towards the use of mass spectrometry as an environmental surveillance tool in detecting pathogenic human viruses in complex environmental samples.


'"/>




Page: 1

Related medicine news :

1. Magnetic Resonance Spectrometry for speedy diagnosis of Brain disorders
2. Laboratory Testing Can Identify Risk of Pre-Term Labor and Delivery
3. Identifying bacteria made amiable
4. Identifying brain lesions with impaired consciousness
5. Identifying Virus Found To Be Essential for HIV Patients
6. Identifying Those At Risk For Diabetes
7. Identifying Predictors Of Anthrax
8. Identifying The Risks Of Developing Schizophrenia
9. Identifying Irregular Heart Beats
10. Identifying Those At Risk For Diabetes
11. Identifying Heart Disease Early
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/29/2016)... ... , ... For those who skip meals occasionally (which is pretty much everyone), ... many new lifestyle diet tips offered by nutritionists Pam Bonney and Priya Lawrence of ... show. Bonny and Lawrence noted that because proper nutrition, including water, provides energy during ...
(Date:4/29/2016)... FL (PRWEB) , ... April 29, 2016 , ... ... will feature Grassland Dairy Products, Inc. in an upcoming episode, airing third quarter ... a century of churning cream into butter, Grassland Dairy Products, located in Greenwood, ...
(Date:4/29/2016)... PLAINSBORO, N.J. (PRWEB) , ... April 29, 2016 ... ... consumer digital and print media enterprise focused entirely on patients with cancer, today ... Mirage, California, was chosen as the 2016 CURE® Extraordinary Healer® for Oncology ...
(Date:4/29/2016)... CA (PRWEB) , ... April 29, 2016 , ... Nike ... long softball camp from July 24th – 27th for girls aged 10-18. All facets ... is held at the beautiful Clark V. Whited Complex, one of the finest softball ...
(Date:4/29/2016)... (PRWEB) , ... April 29, 2016 , ... International Dehydrated ... Seminar on May 3 and 4 at the Doubletree by Hilton Hotel in Oak ... dedicated to marketing and applications technologies for protein ingredients. , At the seminar, IDF™ ...
Breaking Medicine News(10 mins):
(Date:4/28/2016)... JERUSALEM , April 28, 2016 ... ), a clinical-stage pharmaceutical company focused on the development of ... participate in the upcoming PIONEERS 2016 conference, presented by ... 5, 2016 in New York . ... overview at the conference. Presentation Details:   ...
(Date:4/28/2016)... , April 28, 2016  ValGenesis, Inc., ... Management Solutions (VLMS) today announced that a ... for sufferers of chronic kidney failure has ... manage their corporate validation process. The global ... software solution to manage their validation processes ...
(Date:4/28/2016)... , April 28, 2016 ... Review, H1 2016" is a report that provides ... helps strengthen R&D pipelines by identifying new targets ... Company Profiles discussed in this H1 ... Farmaceutiche Riunite Srl, AbbVie Inc., Abiogen Pharma S.p.A., ...
Breaking Medicine Technology: