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Marijuana can Trigger Psychotic Symptoms, New Study Finds

said Dr. Deepak Cyril D'Souza, an associate professor of psychiatry at Yale University's School of Medicine. "In practice, we found that cannabis is very bad for people with schizophrenia," he said.

While D'Souza had intended to study marijuana's impact on schizophrenics in more patients, the study was stopped prematurely because the impact was so pronounced that it would have been unethical to test it on more people with schizophrenia.

"One of the great puzzles is why people with schizophrenia keep taking the stuff when it makes the paranoia worse,'' said Dr. Robin Murray, a professor of psychiatry at King's College.

Experts theorized that schizophrenics may mistakenly judge the drug's pleasurable effects to outweigh any negatives.

Understanding how marijuana affects the brain may ultimately lead experts to a better understanding of mental health in general.

"We don't know the basis of paranoia or anxiety,'' said McGuire.

"It is possible that we could use cannabis in controlled studies to understand psychoses better,'' he said. McGuire theorized that could one day lead to specific drugs targeting the responsible regions of the brain.
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