Navigation Links
Marijuana Use Can Compromise Pregnancy

A woman who uses marijuana at the time of conception or in early pregnancy can compromise the outcome of her pregnancy according to a new study in mice.//

The author of the study Sudhansu Dey, Dorothy Overall Wells professor of pediatrics, cell and developmental biology and pharmacology at Vanderbilt University Medical Center, published his findings in the August issue of the Journal of Clinical Investigation. The study found that THC, the active ingredient in marijuana, can disrupt the body's finely tuned signaling system and interfere with a fertilized egg's ability to implant in the lining of the uterus.

Dey, his colleagues conducted their experiments in mice. Marijuana is known to be the most widely used illegal drug among women of childbearing age. In the body it acts by binding to two receptors, called cannabinoid receptors 1 and 2 (CB1 and 2). These are the receptors found in the brain as well as in sperm, eggs and newly formed embryos. In normal conditions the two receptors are activated by a signaling molecule called anandamide, which is synthesized by an enzyme known as NAPE-PLD and then is degraded by another enzyme called FAAH. This balance, or "tone," of the anandamide is crucial for the embryo to develop normally. When Dey and his team suppressed FAAH activity in the mice they found that the level of anandamide was increased, which is similar to what happens in the body of a woman who smokes marijuana causing an increase in the level of THC which binds to the same receptor as anandamide. The levels of anandamide rise when FAAH activity is suppressed in the embryos and oviduct. This prevents embryos from completing their passage to the uterus, thereby leading to pregnancy being compromised.

Dey said, "This is a major finding that if you block FAAH and disturb anandamide levels, there is a compromised pregnancy outcome. This occurs very early during pregnancy, right from the start of fertilization."

He said, "This m ay explain tubal pregnancies, it may be one cause of retention of embryos in the oviduct." He stressed that the experiment was only in mice.

This study has revealed what happens if you block the FAAH. Other research, also in animals, has suggested that pregnant women who smoke pot can pass on memory problems to their offspring.


'"/>




Related medicine news :

1. Marijuana gateway theory strengthened by study of twins
2. Marijuana Use Could Result In Psychosis
3. Wife May Determine Husband’s Marijuana Use
4. E-Mail Affects Brain More Than Marijuana
5. Marijuana-Derived Drug Promises Hope In Treating Bladder Infection
6. Adolescent Marijuana Smokers Face Risk Of Developing Schizophrenia
7. Rhode Island legalizes use and possession of Marijuana
8. Smoking Marijuana Increases The Risk Of Bladder Cancer
9. Marijuana Compound Offers Hope In Diabetic Retinopathy Prevention
10. Marijuana Causes The Brain To Lose Its Ability
11. Cancer Patient to Appeal to SC, Demanding Right to Use Marijuana
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/27/2017)... ... June 27, 2017 , ... Today, June 27th is PTSD Awareness Day. Over ... 20% will receive adequate care due to lack of effective treatments, fear of stigma ... all. And left untreated, veterans are at an increased risk for self-destructive behavior, including ...
(Date:6/27/2017)... ... ... Children’s National Health System received top honors in the 2017-18 U.S News & ... of more than 1500 neonatal intensive care units coast to coast. Children’s ... the top performing children’s hospitals in the country. , In addition to achieving ...
(Date:6/26/2017)... ... June 26, 2017 , ... Dr. Martin ... Specialists, in collaboration with the Fertility Center of California, is pleased to announce ... epidydimal sperm aspiration) and TESA (percutaneous testicular sperm extraction). These minimally invasive treatments ...
(Date:6/26/2017)... Mexico (PRWEB) , ... June 26, 2017 , ... ... anorgasmia, and urinary leakage is revolutionizing the way women look and feel about ... tackling the problem of female sexual dysfunction and urinary leakage head on with ...
(Date:6/26/2017)... ... 26, 2017 , ... KICKICO , a protocol built on Ethereum for ... many catastrophic issues within funding campaigns. KICKICO developers are testing the platform, which will ... the raising of funds through the power of many - has been around for ...
Breaking Medicine News(10 mins):
(Date:6/8/2017)... 8, 2017   Responding to Heath Ledger,s ... death of singer Chris Cornell in May, the ... offers a free online psychiatric drug side ... families about psychotropic drug risks. The father ... from an accidental overdose, has called for tighter rules on ...
(Date:6/7/2017)... June 7, 2017  Novavax, Inc., (Nasdaq: NVAX ... Phase 2 trials of its RSV F protein recombinant nanoparticle ... age have been published in the journal Vaccine ... shared in prior scientific conferences). The Company previously announced ... Novavax is developing the RSV F Vaccine with the goal ...
(Date:6/5/2017)... Kohll,s Pharmacy & Homecare is the first distributor of ... . The Raizer is a simple battery operated mobile ... an almost-standing position within a few minutes. The ... and does not require any extra effort besides a ... can operate it, and lightweight and portable so ...
Breaking Medicine Technology: