Navigation Links
Marijuana Use Can Compromise Pregnancy

A woman who uses marijuana at the time of conception or in early pregnancy can compromise the outcome of her pregnancy according to a new study in mice.//

The author of the study Sudhansu Dey, Dorothy Overall Wells professor of pediatrics, cell and developmental biology and pharmacology at Vanderbilt University Medical Center, published his findings in the August issue of the Journal of Clinical Investigation. The study found that THC, the active ingredient in marijuana, can disrupt the body's finely tuned signaling system and interfere with a fertilized egg's ability to implant in the lining of the uterus.

Dey, his colleagues conducted their experiments in mice. Marijuana is known to be the most widely used illegal drug among women of childbearing age. In the body it acts by binding to two receptors, called cannabinoid receptors 1 and 2 (CB1 and 2). These are the receptors found in the brain as well as in sperm, eggs and newly formed embryos. In normal conditions the two receptors are activated by a signaling molecule called anandamide, which is synthesized by an enzyme known as NAPE-PLD and then is degraded by another enzyme called FAAH. This balance, or "tone," of the anandamide is crucial for the embryo to develop normally. When Dey and his team suppressed FAAH activity in the mice they found that the level of anandamide was increased, which is similar to what happens in the body of a woman who smokes marijuana causing an increase in the level of THC which binds to the same receptor as anandamide. The levels of anandamide rise when FAAH activity is suppressed in the embryos and oviduct. This prevents embryos from completing their passage to the uterus, thereby leading to pregnancy being compromised.

Dey said, "This is a major finding that if you block FAAH and disturb anandamide levels, there is a compromised pregnancy outcome. This occurs very early during pregnancy, right from the start of fertilization."

He said, "This m ay explain tubal pregnancies, it may be one cause of retention of embryos in the oviduct." He stressed that the experiment was only in mice.

This study has revealed what happens if you block the FAAH. Other research, also in animals, has suggested that pregnant women who smoke pot can pass on memory problems to their offspring.


'"/>




Related medicine news :

1. Marijuana gateway theory strengthened by study of twins
2. Marijuana Use Could Result In Psychosis
3. Wife May Determine Husband’s Marijuana Use
4. E-Mail Affects Brain More Than Marijuana
5. Marijuana-Derived Drug Promises Hope In Treating Bladder Infection
6. Adolescent Marijuana Smokers Face Risk Of Developing Schizophrenia
7. Rhode Island legalizes use and possession of Marijuana
8. Smoking Marijuana Increases The Risk Of Bladder Cancer
9. Marijuana Compound Offers Hope In Diabetic Retinopathy Prevention
10. Marijuana Causes The Brain To Lose Its Ability
11. Cancer Patient to Appeal to SC, Demanding Right to Use Marijuana
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/25/2017)... ... April 25, 2017 , ... Vetoquinol ... is introducing Flexadin UCII, part of the EQUISTRO line, at this week’s Rolex ... in horses at the immunologic level. , The scientifically-developed Flexadin UCII supports the ...
(Date:4/24/2017)... ... April 24, 2017 , ... Michael Vick announced his retirement earlier this ... The former overall number one pick in the 2001 NFL Draft, to the Atlanta ... record for the most career rushing yards by a quarterback (6,109) and the most ...
(Date:4/24/2017)... ... April 24, 2017 , ... NEPC Director Kevin Welner ... Education Research Award. The award honors scholars exemplary in their capacity to communicate ... who has demonstrated the capacity to deepen the public’s understanding and appreciation of ...
(Date:4/24/2017)... ... April 24, 2017 , ... Sean Fay is the undisputed ... Sonicare Toothbrush, Juiceman Juicer, and the George Foreman Grill (which sold more than 100 ... in the last 25 years. , Now, due to changes in the broadcast media ...
(Date:4/24/2017)... ... April 24, 2017 , ... The world-class designers ... to bring their novel lifesaving device for the everyday use of parents worldwide. ... specially designed to read a child’s vital signs, and detect unusual symptoms or ...
Breaking Medicine News(10 mins):
(Date:4/21/2017)... 2017 Halo Labs announces the launch of ... system called the Horizon at PEGS 2017 in ... system analyzes sub visible particulate matter in biopharmaceutical samples ... as early as candidate selection and pre-formulation. ... research organization Elion Labs for system validation. ...
(Date:4/20/2017)... DUBLIN , April 20, 2017 ... the "Global Biosimilar Pipeline and Market Prospects: Addressing ... report to their offering. ... "Global Biosimilar Pipeline and Market ... by Design" provides an in-depth assessment of the current ...
(Date:4/20/2017)... 20, 2017   ZappRx, Inc ., a digital health ... process, today announced it closed $25 million in Series B ... firm based in Seattle that is ... . The Series B round included participation from SR ... and GV (formerly Google Ventures). As part of ...
Breaking Medicine Technology: