Navigation Links
Marijuana Use Can Compromise Pregnancy

A woman who uses marijuana at the time of conception or in early pregnancy can compromise the outcome of her pregnancy according to a new study in mice.//

The author of the study Sudhansu Dey, Dorothy Overall Wells professor of pediatrics, cell and developmental biology and pharmacology at Vanderbilt University Medical Center, published his findings in the August issue of the Journal of Clinical Investigation. The study found that THC, the active ingredient in marijuana, can disrupt the body's finely tuned signaling system and interfere with a fertilized egg's ability to implant in the lining of the uterus.

Dey, his colleagues conducted their experiments in mice. Marijuana is known to be the most widely used illegal drug among women of childbearing age. In the body it acts by binding to two receptors, called cannabinoid receptors 1 and 2 (CB1 and 2). These are the receptors found in the brain as well as in sperm, eggs and newly formed embryos. In normal conditions the two receptors are activated by a signaling molecule called anandamide, which is synthesized by an enzyme known as NAPE-PLD and then is degraded by another enzyme called FAAH. This balance, or "tone," of the anandamide is crucial for the embryo to develop normally. When Dey and his team suppressed FAAH activity in the mice they found that the level of anandamide was increased, which is similar to what happens in the body of a woman who smokes marijuana causing an increase in the level of THC which binds to the same receptor as anandamide. The levels of anandamide rise when FAAH activity is suppressed in the embryos and oviduct. This prevents embryos from completing their passage to the uterus, thereby leading to pregnancy being compromised.

Dey said, "This is a major finding that if you block FAAH and disturb anandamide levels, there is a compromised pregnancy outcome. This occurs very early during pregnancy, right from the start of fertilization."

He said, "This m ay explain tubal pregnancies, it may be one cause of retention of embryos in the oviduct." He stressed that the experiment was only in mice.

This study has revealed what happens if you block the FAAH. Other research, also in animals, has suggested that pregnant women who smoke pot can pass on memory problems to their offspring.


'"/>




Related medicine news :

1. Marijuana gateway theory strengthened by study of twins
2. Marijuana Use Could Result In Psychosis
3. Wife May Determine Husband’s Marijuana Use
4. E-Mail Affects Brain More Than Marijuana
5. Marijuana-Derived Drug Promises Hope In Treating Bladder Infection
6. Adolescent Marijuana Smokers Face Risk Of Developing Schizophrenia
7. Rhode Island legalizes use and possession of Marijuana
8. Smoking Marijuana Increases The Risk Of Bladder Cancer
9. Marijuana Compound Offers Hope In Diabetic Retinopathy Prevention
10. Marijuana Causes The Brain To Lose Its Ability
11. Cancer Patient to Appeal to SC, Demanding Right to Use Marijuana
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/25/2016)... ... 2016 , ... Indiana Fiber Network, LLC (IFN), the leading ... as a fiber transport provider. IFN provided Lake City Bank with network services ... , “IFN provides fiber transport to Lake City Bank, which includes protected ...
(Date:5/25/2016)... ... 2016 , ... Today Omega Institute, a leading destination for yoga education in ... opportunities in the growing field of yoga therapy . Yoga therapy adapts ... specific health issues—including injuries, illnesses, and temporary or chronic health conditions. , “Yoga therapy ...
(Date:5/25/2016)... ... May 25, 2016 , ... Afrimesure specializes ... medical and pharmaceutical, to food and HVAC facilities. Their knowledgeable staff also takes ... , For medical applications, Afrimesure offers a variety of MadgeTech systems available for ...
(Date:5/25/2016)... Pittsburgh, Pa. (PRWEB) , ... May 25, 2016 , ... ... announced today that Carol Reichbaum, M.S.L., M.S.P.A., of the University of Pittsburgh Graduate ... , The Fellowship will enable Ms. Reichbaum and 24 other advocates from around the ...
(Date:5/25/2016)... ... May 25, 2016 , ... Researchers from SUNY State College of Optometry ... work on visual evoked potential and human attention. The article, VEP and Human ... Diopsys® NOVA™ ERG and VEP Vision Testing System (Diopsys, Inc., Pine Brook, NJ) ...
Breaking Medicine News(10 mins):
(Date:5/24/2016)... 24, 2016 Een app die ... zij collectief patiënten kunnen behandelen, hun kennis kunnen delen ... achter de nieuwe en revolutionaire MDLinking App, ontwikkeld door ... vaatchirurg dr. Hans Flu en oncologisch chirurg dr. ... beschikbaar is, wordt op dinsdag 24 mei officieel gepresenteerd ...
(Date:5/23/2016)... May 23, 2016 Transparency Market ... Exocrine Pancreatic Insufficiency Market - Global Industry Analysis, Size, ... According to the report, the exocrine pancreatic insufficiency market ... from 2015 to 2023 to reach US$2.85 Bn by ... condition characterized by the deficiency of the exocrine pancreatic ...
(Date:5/23/2016)... 23, 2016 Non-invasive diagnostic test ... multiple diseases; ,Technology to be presented at Yissum’s booth, ... Research Development Company of the Hebrew University of Jerusalem ... agreement with Aurum Ventures MKI, the technology investment arm of ... new diagnostic approach for early detection of multiple diseases ...
Breaking Medicine Technology: