Navigation Links
Marijuana Use Can Compromise Pregnancy

A woman who uses marijuana at the time of conception or in early pregnancy can compromise the outcome of her pregnancy according to a new study in mice.//

The author of the study Sudhansu Dey, Dorothy Overall Wells professor of pediatrics, cell and developmental biology and pharmacology at Vanderbilt University Medical Center, published his findings in the August issue of the Journal of Clinical Investigation. The study found that THC, the active ingredient in marijuana, can disrupt the body's finely tuned signaling system and interfere with a fertilized egg's ability to implant in the lining of the uterus.

Dey, his colleagues conducted their experiments in mice. Marijuana is known to be the most widely used illegal drug among women of childbearing age. In the body it acts by binding to two receptors, called cannabinoid receptors 1 and 2 (CB1 and 2). These are the receptors found in the brain as well as in sperm, eggs and newly formed embryos. In normal conditions the two receptors are activated by a signaling molecule called anandamide, which is synthesized by an enzyme known as NAPE-PLD and then is degraded by another enzyme called FAAH. This balance, or "tone," of the anandamide is crucial for the embryo to develop normally. When Dey and his team suppressed FAAH activity in the mice they found that the level of anandamide was increased, which is similar to what happens in the body of a woman who smokes marijuana causing an increase in the level of THC which binds to the same receptor as anandamide. The levels of anandamide rise when FAAH activity is suppressed in the embryos and oviduct. This prevents embryos from completing their passage to the uterus, thereby leading to pregnancy being compromised.

Dey said, "This is a major finding that if you block FAAH and disturb anandamide levels, there is a compromised pregnancy outcome. This occurs very early during pregnancy, right from the start of fertilization."

He said, "This m ay explain tubal pregnancies, it may be one cause of retention of embryos in the oviduct." He stressed that the experiment was only in mice.

This study has revealed what happens if you block the FAAH. Other research, also in animals, has suggested that pregnant women who smoke pot can pass on memory problems to their offspring.


Related medicine news :

1. Marijuana gateway theory strengthened by study of twins
2. Marijuana Use Could Result In Psychosis
3. Wife May Determine Husband’s Marijuana Use
4. E-Mail Affects Brain More Than Marijuana
5. Marijuana-Derived Drug Promises Hope In Treating Bladder Infection
6. Adolescent Marijuana Smokers Face Risk Of Developing Schizophrenia
7. Rhode Island legalizes use and possession of Marijuana
8. Smoking Marijuana Increases The Risk Of Bladder Cancer
9. Marijuana Compound Offers Hope In Diabetic Retinopathy Prevention
10. Marijuana Causes The Brain To Lose Its Ability
11. Cancer Patient to Appeal to SC, Demanding Right to Use Marijuana
Post Your Comments:

(Date:11/27/2015)... ... November 27, 2015 , ... Lizzie’s Lice Pickers just announced a ... customers 10% off of their purchase of lice treatment product. In addition, customers will ... to a company spokesperson. “Finding lice is a sure way to ruin the holidays, ...
(Date:11/27/2015)... VVA (PRWEB) , ... November 27, 2015 , ... ... motto of progress through sharing, the 2016 Building Better Radiology Marketing ... The conference will begin on Sunday, March 6, 2016, at Caesars Palace in ...
(Date:11/27/2015)... ... November 27, 2015 , ... Keeping in mind ... mental health and wellness consultation, has collaborated with a leading web-based marketplace for ... gap experienced by parents and bring advice from parenting experts within their reach. ...
(Date:11/27/2015)... San Francisco, California (PRWEB) , ... November 27, 2015 , ... ... 1969 Janis Joplin Ann Arbor Michigan boxing style concert posters. This is one of ... 1969 at the Canterbury House at the University of Michigan in Ann Arbor. The ...
(Date:11/26/2015)... ON (PRWEB) , ... November 26, 2015 , ... ... of a real-time eReferral system for diagnostic imaging in the Waterloo region. Using ... BMD and Nuclear Medicine tests directly from their electronic medical record (EMR) without ...
Breaking Medicine News(10 mins):
(Date:11/27/2015)... , November 27, 2015 ... is set to go online. The potential to save ... is vast and far from fully exploited as yet. ... patient health records, either via mobile tablet or directly ... --> ) --> ...
(Date:11/27/2015)... , Nov. 26, 2015 ... addition of the "2016 Global Tumor ... Country Volume and Sales Segment Forecasts, Innovative ... report to their offering. --> ... of the "2016 Global Tumor Marker ...
(Date:11/26/2015)... November 26, 2015 --> ... combination approach blends immunotherapy with Bremachlorin-photodynamic therapy for advanced ... approach blends immunotherapy with Bremachlorin-photodynamic therapy for advanced cancer. ... approach blends immunotherapy with Bremachlorin-photodynamic therapy for advanced cancer. ... has found that immunotherapy can be efficiently combined with ...
Breaking Medicine Technology: