Navigation Links
Many Drug Tests on Animals are Badly Flawed, a Study Warns

A BMJ Study in six areas by team of senior scientists warns that many tests of drugs on animals// are flawed and hard to predict how well a prototype medicine will work on humans.

The British Medical Journal (BMJ) research, which looked at the studies in six areas have found that animal studies agreed with human trials in just three areas out of six.

It is believed that the high-profile London drug trial that left six men ill early this year was carried out after animal studies showed the drug TGN1412 was effective, but resulted in six men suffering from serious organ failure after taking part in a trial of the TGN1412 drug made by TeGenero.

A team of researchers from the London School of Hygiene and Tropical Medicine reviewed evidence from a wide range of human and animal trials looking at six areas of treatment. This study was led by Professor Ian Roberts and suggested that the animal studies should be used only if required.

Corticosteroids, which were used to treat head injuries and respiratory illnesses in babies, Antifibrinolytics to treat bleeding, Thrombolysis and Tirilazad for stroke and Bisphosphonates for osteoporosis. But found that there was no consistent agreement between the animal and human studies.

These drugs did not show any benefits for treating diseases, for example Corticosteroids did not show any benefit for treating head injury in clinical trials but had done so in animal models. Different results were seen for tirilazad, for which data from animal studies suggested a benefit but the human trials showed no benefit, but only possible harm. But in some cases, for example in case of osteoporosis (brittle bones) and neonatal respiratory distress, where babies struggle to breathe, the clinical trials in animals came up with the same result as the human trials.

To conclude, the researchers have called in for more systematic reviews like this one, where the results of a number of an
'"/>




Page: 1 2

Related medicine news :

1. The Effectiveness Of Screening Tests Questioned
2. Blood Tests Can Help Detect Osteoporosis Early In Life
3. Easier Tests To Detect Tuberculosis
4. Fragile X-Associated Tremor /Ataxia Syndrome Need Guidelines For Diagnostic Tests
5. Genetic Tests Could Become As Affordable As Blood Tests
6. Obese Adults Undergo Less Medical Tests And More Vulnerable To Diseases
7. Delay in Breast Cancer Gene Tests
8. Health Officials Inquire Into OraQuick HIV Tests
9. Move to make HIV Tests mandatory For Soldiers In Northeast
10. Punjab Government To Clamp Down On Sex Determination Tests
11. Free HIV Tests Brings Crowd to the Testing Centers
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Many Drug Tests Animals are Badly Flawed Study Warns

(Date:10/19/2014)... 2014 Having been working in the garment ... of customer needs. According to James, one of the company’s ... sequins, or with high-low skirts that add beauty to them. ... Recently, LunaDress has unveiled its new selection of 2014 long ... company’s brand new items are available in over 20 popular ...
(Date:10/19/2014)... (PRWEB) October 20, 2014 Recently, Fancyflyingfox.com, ... special occasion clothes, has announced its latest designs of ... addition, all the new elegant outfits are offered with ... place an order before October 30 can enjoy this ... and great marketing strategies, it has become one of ...
(Date:10/19/2014)... 2014 Visual Impact Frequency Training ... been released to the public generating a frenzied ... and fitness community. The commotion surrounding the program's ... Delmonico prompting an investigative review. , "Many gym-goers ... is commonly known as a training 'plateau' where ...
(Date:10/19/2014)... News) -- New stem cell-based research could improve understanding ... a new study suggests. Scientists used stem cells ... a lab dish. They then transplanted the organoids into ... according to the researchers. "This provides a new ... can cause intestinal failure, from genetic disorders appearing at ...
(Date:10/19/2014)... 2014 – The U.S. Government has initiated a ... disease by 2025. However, a workgroup of nearly ... milestones in the U.S. Government,s National Plan to ... increased in scale, and adequately funded in order ... proposals by the workgroup to enlarge and strengthen ...
Breaking Medicine News(10 mins):Health News:2014 Long Prom Dresses From LunaDress Now Available In Over 20 Popular Designs 2Health News:Fancyflyingfox.com Updates Its Website With New Mother Of The Bride Dresses For 2014 2Health News:Visual Impact Frequency Training Review: Rusty Moore's Latest Fitness Guide Released 2Health News:Scientists Grow, Implant Human Intestinal Tissue in Mice 2Health News:Scientists say national Alzheimer's plan milestones must be strengthened to meet goal by 2025 2Health News:Scientists say national Alzheimer's plan milestones must be strengthened to meet goal by 2025 3Health News:Scientists say national Alzheimer's plan milestones must be strengthened to meet goal by 2025 4Health News:Scientists say national Alzheimer's plan milestones must be strengthened to meet goal by 2025 5Health News:Scientists say national Alzheimer's plan milestones must be strengthened to meet goal by 2025 6
... has been mapped for the first time by ... procedure, developed by scientists from the MPI for ... in primate brains by means of the BOLD-Signal ... electrical microstimulation and FMRT promises more precise insights ...
... a study done at Cornell University it has been found ... then those who are not.// ,The study was ... inadequate eating reflects in impaired academic development especially in reading. ... This is the condition when children do not have enough ...
... State University researchers Robin W. Simon, Vanderbilt University, and ... be linked to higher levels of depression. Certain types ... of depression. This has been published in the Journal ... Families and Households data was utilized for the analysis. ...
... paper on cloning that rocked the world about cloning from ... Korean scientist Hwang was found guilty by a university panel.// ... his actions. , ,This has been taken very ... pledged to impose an unspecified heavy punishment on Hwang. The ...
... generic drug version of the Tamiflu anti-flu ... Tamiflu drug his under great international pressure ... to manufacture // generic drugs as most ... not afford the drug. The new generic ...
... Committee on Economic Affairs has approved to extend by five ... five million people.// ,The extension of the program from ... expenditure of Rs.11.56 billion ($255 million). Of this, Rs.2.82 billion ... billion in the 11th Plan (2007-12). ,"The direct benefit ...
Cached Medicine News:Health News:New Procedure Reveals the Secrets of the Brain 2Health News:A forgery: the cloning (controversy) research 2
(Date:10/20/2014)... , Oct. 20, 2014  Indianapolis interventional ... Toronto -based 3D visualization leader ... Congress of Neurological Surgeons Annual Meeting that they ... for brain surgery. The collaboration is the first ... combination to improve patient outcomes. NICO,s BrainPath® interventional ...
(Date:10/20/2014)...  ResMed (NYSE: RMD ) today ... program, a comprehensive suite of software and service ... health care providers. ResMed Data ... information. It integrates valuable sleep and respiratory treatment ... platforms with customers, in-house or third-party electronic health ...
(Date:10/20/2014)... , Oct. 20, 2014   BioNano Genomics announced ... the ability to collect human data at 30X depth, sufficient ... chip.  This new capability was established and demonstrated for the ... Irys TM System and will be rolled out ... BioNano will be showcasing this advancement at the American ...
Breaking Medicine Technology:Indianapolis' NICO Corporation and Toronto's Synaptive Medical, Inc. Announce First-Ever Intervention-Visualization Partnership with Goal to Improve Standard of Care in Neurosurgery 2Indianapolis' NICO Corporation and Toronto's Synaptive Medical, Inc. Announce First-Ever Intervention-Visualization Partnership with Goal to Improve Standard of Care in Neurosurgery 3Indianapolis' NICO Corporation and Toronto's Synaptive Medical, Inc. Announce First-Ever Intervention-Visualization Partnership with Goal to Improve Standard of Care in Neurosurgery 4Indianapolis' NICO Corporation and Toronto's Synaptive Medical, Inc. Announce First-Ever Intervention-Visualization Partnership with Goal to Improve Standard of Care in Neurosurgery 5ResMed Launches ResMed Data Exchange 2BioNano Genomics Announces One Human : One Chip : One Day 2BioNano Genomics Announces One Human : One Chip : One Day 3
... Medical Alarm Concepts Holding, Inc. (OTCQ:MDHI), manufacturer of ... allows the user to speak and listen directly through ... its next generation medical alarm, and hopes to release ... will have enhanced features, including but not limited to, ...
... In the near future, packaging and transport equipment ... as goods move through the supply chain, according to ... computing models that allow products and packaging to communicate ... and other points throughout the chain. This will create ...
Cached Medicine Technology:Medical Alarm Concepts Announces Beta Testing of Next Generation MediPendant™ Medical Alarm Technology! 2Medical Alarm Concepts Announces Beta Testing of Next Generation MediPendant™ Medical Alarm Technology! 3BT Delivers Vision of Intelligent Supply Chain at LogiPharma Conference 2
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: