Navigation Links
Many Drug Tests on Animals are Badly Flawed, a Study Warns

A BMJ Study in six areas by team of senior scientists warns that many tests of drugs on animals// are flawed and hard to predict how well a prototype medicine will work on humans.

The British Medical Journal (BMJ) research, which looked at the studies in six areas have found that animal studies agreed with human trials in just three areas out of six.

It is believed that the high-profile London drug trial that left six men ill early this year was carried out after animal studies showed the drug TGN1412 was effective, but resulted in six men suffering from serious organ failure after taking part in a trial of the TGN1412 drug made by TeGenero.

A team of researchers from the London School of Hygiene and Tropical Medicine reviewed evidence from a wide range of human and animal trials looking at six areas of treatment. This study was led by Professor Ian Roberts and suggested that the animal studies should be used only if required.

Corticosteroids, which were used to treat head injuries and respiratory illnesses in babies, Antifibrinolytics to treat bleeding, Thrombolysis and Tirilazad for stroke and Bisphosphonates for osteoporosis. But found that there was no consistent agreement between the animal and human studies.

These drugs did not show any benefits for treating diseases, for example Corticosteroids did not show any benefit for treating head injury in clinical trials but had done so in animal models. Different results were seen for tirilazad, for which data from animal studies suggested a benefit but the human trials showed no benefit, but only possible harm. But in some cases, for example in case of osteoporosis (brittle bones) and neonatal respiratory distress, where babies struggle to breathe, the clinical trials in animals came up with the same result as the human trials.

To conclude, the researchers have called in for more systematic reviews like this one, where the results of a number of an imal trials are pooled to get a better idea on the effects of drugs.


'"/>




Related medicine news :

1. The Effectiveness Of Screening Tests Questioned
2. Blood Tests Can Help Detect Osteoporosis Early In Life
3. Easier Tests To Detect Tuberculosis
4. Fragile X-Associated Tremor /Ataxia Syndrome Need Guidelines For Diagnostic Tests
5. Genetic Tests Could Become As Affordable As Blood Tests
6. Obese Adults Undergo Less Medical Tests And More Vulnerable To Diseases
7. Delay in Breast Cancer Gene Tests
8. Health Officials Inquire Into OraQuick HIV Tests
9. Move to make HIV Tests mandatory For Soldiers In Northeast
10. Punjab Government To Clamp Down On Sex Determination Tests
11. Free HIV Tests Brings Crowd to the Testing Centers
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/8/2016)... ... ... David J. Dykeman , Ginger Pigott , and J. Rick ... West, Dec. 12, 2016, at the Fairmont Newport Beach in California. Greenberg Traurig is ... Sciences & Medical Technology Group have been featured speakers at every DeviceTalks conference since ...
(Date:12/8/2016)... ... December 08, 2016 , ... SunView Software aims to redefine ... are both engaging and easy to use. Coming off the heels of a ... today its plans to roll out new AI-powered self-service enhancements to help organizations ...
(Date:12/8/2016)... ... December 08, 2016 , ... ... solutions for drugs, biologics and consumer health products, today announced that it had ... in 2006 as a non-profit organization to unite pharmaceutical and healthcare companies that ...
(Date:12/8/2016)... (PRWEB) , ... December 08, 2016 , ... STAT courier ... to be a convenient service for Texas, they are expanding their presence in Dallas. ... a hiring spree that will bring new jobs to the Dallas and Forth Worth ...
(Date:12/8/2016)... ... December 08, 2016 , ... Today’s ... possible. With this in mind, SIGVARIS has created a new line of anti-embolism ... bed rest and provide the benefits of graduated compression when transitioning from recovery ...
Breaking Medicine News(10 mins):
(Date:12/9/2016)... -- Research and Markets has announced the addition ... report to their offering. ... Market growth can be attributed ... pharmaceutical and biotechnology industry and technological advancements like automation and ... and growing research activities in toxicology and stem cells provide ...
(Date:12/9/2016)... Research and Markets has announced the addition of the ... ... travel vaccines market to grow at a CAGR of 6.83% during ... and the growth prospects of the global travel vaccines market for ... generated from the sales of various vaccines administered to actively immunize ...
(Date:12/8/2016)... Dec. 8, 2016 Australia Ophthalmic Lasers Market ... "Australia Ophthalmic Lasers Market Outlook to 2022", provides key ... report provides value, in millions of US dollars, volume ... - Excimer Lasers, Femtosecond Lasers and YAG Lasers. ... data for each of these market segements, and global ...
Breaking Medicine Technology: