Researchers have found traces of a monkey virus that contaminated the polio vaccine in the early 50's in a common form of highly malignant human cancer that has mystically doubled in incidence over the past 30 years. Two studies, found a link between the virus, called SV40, and non-Hodgkin lymphomas, a disorder ranked fourth or fifth among cancer deaths in the United States among women and men, respectively. //
Results suggest that the virus may play a much wider role in cancer than previously suspected. Dr. Janet Butel, a lead researcher of the study at Bayor College, No obvious risk factors have emerged for non-Hodgkin lymphoma in the general population, but a viral cause has been postulated,'' said a group of eight researchers at Baylor College of Medicine in Texas led by Dr. Janet Butel. ``This finding sheds new light on the possible genesis of (this) important group of malignant disorders.''
The scientists added that their findings may also offer hope for new therapies for the malignancies. The Salk polio vaccine, administered by injection in the United States and worldwide from 1950 through 1960, was grown on minced kidney tissue from rhesus monkeys.
At the time, the manufacturing process was considered safe. But in 1960, it was discovered that large batches of the vaccine were contaminated with the simian virus later named SV40. An estimated 90 million Americans received Salk vaccine injections and as many as 30 million were exposed to the virus.
In laboratory tests, hamsters injected with SV40 developed a variety of malignant tumors, but early government studies indicated that the virus appeared to have no negative effect in humans who had been exposed. That view began to change in the 1990s when DNA detection techniques became much more refined and evidence of the virus started showing up in human tumors. The group included rare brain, bone and lung-related cancers called mesotheliomas.
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