Navigation Links
Male Contraceptive Drug - Non Hormonal Alternative

A contraceptive drug for men , based on a non hormonal approach is being studied by scientists. Until now , the fact that an adult male usually produces// 150 million sperm has made the formulation of a male birth control pill diffcult.

Final clinical trials are being done on a hormonal male pill , based on progesterone - a female hormone that inhibits the formation of sperm - and testosterone, the male hormone added to counter the adverse effects of progesterone. But this does not appeal to most men who have fears of the progesterone affecting their masculinity , in spite of lack of evidence of such a likelihood.

Chuen Yan Cheng of the Population Council in New York is pioneering a new approach to get around this problem . This method involves a a chemical called adherin which blocks the development of sperm temporarily , and does not alter the sex hormone ratio in the body. Studies on rats have also shown that there are no serious side effects on the heart, kidney, lungs and other vital organs in the long term.

During spermatogenesis when sperms are being manufactured in the testes, they are helped in their development into mature sperm by special tissue called Sertoli cells. Adherin acts by breaking the bond between the immature sperm and the Sertoli cells. Therefore the male hormones are not affected at all.

Adherin is toxic on its own in high doses. By binding it with a synthetic follicle stimulating hormone( FSH), which attaches itself only to the Sertoli cell, scientists could use much lower doses. The results of a study in rats showed that sperm production decreased , resulting in complete infertility. The rats started producing normal amounts of sperm once the drug had been eliminated from their blood stream, so the infertility is reversible.

This factor, Dr.Cheng feels, would set people's mind at rest, so they would be more willing to use the drug. A lot of work remains to be done before these finding s can be used safely and effectively in humans .The drug would most likely have to be used as an implant in men as it breaks down in the digestive tract.

Similar studies have been done by a research team led by Dr Dolores Mruk, from the Centre For Biomedical Research in New York. Dr Richard Anderson, from the University of Edinburgh, who has been involved in the hormonal contraception research in the UK, says that these findings are promising , and could lead to an attractive option.
MAL
'"/>




Related medicine news :

1. Contraceptives via Internet
2. FDA Approves Contraceptive Ring
3. Contraceptives decreases Libido
4. Contraceptives have dual effects
5. Drugs For Anthrax May Interfere With Oral Contraceptives
6. Contraceptive pill to reduce PMS
7. Smoking and Oral Contraceptives:
8. Contraceptive pills may lead to deformities in babies
9. Low-Dose Oral Contraceptives May Increase Risk For Heart Attack Or Stroke
10. Prevent Multiple Sclerosis From Oral Contraceptives
11. Usage Of Oral Contraceptives Need Not Be Feared By SLE Patients
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/24/2017)... PARK (PRWEB) , ... July 24, 2017 , ... Engineers ... is bio-compatible, because it produces the same kind of electrical energy that the body ... the form of moving electrons. This flow of electrons out of the battery is ...
(Date:7/24/2017)... ... , ... Cheerag D. Upadhyaya , M.D., M.Sc., FAANS has been appointed ... part of Saint Luke’s Health System . Dr. Upadhyaya has served in the ... FAANS joins Stanley P. Fisher, M.D., who has served as medical co-director ...
(Date:7/24/2017)... , ... July 24, 2017 , ... Cosmetic Town, an ... and the cosmetic surgeries they perform on a daily basis. , The new ... surgery procedures they specialize in at their practices. , When asked about the ...
(Date:7/24/2017)... ... 2017 , ... Horizon Goodwill Industries, SourceAmerica and ... high school girls succeed in STEM programs as well as help Horizon Goodwill ... over 20 high school girls at their corporate headquarters on Tuesday, July 25, ...
(Date:7/24/2017)... ... July 24, 2017 , ... Peruvian ... awards to be awarded annually to and divided between two full-time university students ... awareness to Amazonian plant medicine. To apply for the scholarship, students are asked ...
Breaking Medicine News(10 mins):
(Date:7/12/2017)...  Eli Lilly and Company (NYSE: LLY ) ... resolve pending patent litigation in the U.S. District Court for ... the Cialis ® (tadalafil) unit dose patent. This patent ... part of the agreement, Cialis exclusivity is now expected to ... "The unit dose patent for Cialis is valid and infringed ...
(Date:7/11/2017)... , July 11, 2017  Sysmex America, Inc., ... diagnostic testing equipment as well as middleware information ... way to make quality assurance easier and more ... is well known for the innovation that it ... Monitor elevates quality assurance processes to a new ...
(Date:7/10/2017)... , July 10, 2017 The Institute for ... methods, is the recipient of a VITROCELL® inhalation exposure ... International Science Consortium. The device, which is designed to ... expose human lung cells to airborne test materials in ... use the VITROCELL® system for testing combustible tobacco products, ...
Breaking Medicine Technology: