Navigation Links
Malaria-resistant Mosquito Developed

Researchers have developed a malaria-resistant mosquito, a step that might one day help block the spread of an illness that has claimed millions// of lives around the world.

When they fed on malaria-infected mice, the resistant mosquitoes had a higher survival rate than nonresistant ones, meaning they could eventually replace the ones that can carry the disease, according to a report in Tuesday's issue of Proceedings of the National Academy of Sciences.

Jason Rasgon of the department of molecular microbiology and immunology at Johns Hopkins University cautioned that the research so far is only a proof of principle and any field tests remain far away.

Nonetheless, it's a goal eagerly sought by scientists in hope of developing a practical way of blocking the spread of malaria.

According to the federal Centers for Disease Control and Prevention, an estimated 700,000 to 2.7 million people die of malaria each year, 75 percent of them African children.

Working with the mouse form of malaria — not the human type — Rasgon's team was able to genetically engineer mosquitoes that were resistant to malaria.

Malaria infection does exact a toll on mosquitoes and in laboratory work they found that the resistant insects were able to compete nonresistant mosquitoes.

Starting with the same number of resistant and nonresistant mosquitoes, they found that after nine generations the resistant type made up 70 percent of the population — raising the possibility of replacing regular mosquitoes with resistant ones that don't spread disease.

However, Rasgon stressed that in the lab work the insects were infected with a higher amount of the parasite than occurs in nature, and a larger proportion of the mosquitoes were infected.

"This was proof of principle," Rasgon said in a telephone interview. "The next step would be to work in a system more epidemiologically relevant" but still in t he lab.

"We're not anywhere near a field release," he said. Now they need to turn their attention to working with human malaria and trying to engineer a mosquito resistant to that.

William C. Black IV, a professor of entomology at Colorado State University, noted that the work was done with Plasmodium berghei, which infects mice, rather than P. falciparum, which causes malaria in humans.

P. berghei is often used in laboratory work because it is easy to manipulate, but a lot of its properties are specific to that parasite and it is not always a good model for the human form, he said.

"On the other hand, finding a gene that confers resistance and is stable for a long period of time is significant," said Black, who was not part of the research team.

If they can repeat the work using the human parasite then there is a chance of taking it into the field, he said.

Dr. Woodbridge A. Foster, an entomologist at Ohio State University who was not part of the research team, said that while several labs have been trying to develop a resistant mosquito, he was not aware of any that had been developed that were both healthy and inhospitable to the malaria parasite.

Source-Bio-Bio Technology
SM
'"/>




Related medicine news :

1. Gene researchers make Malaria-resistant mosquito
2. Malaria To Be Tackled By Genetically Modified Mosquitoes
3. India Has The Oldest And Largest Collection Of Preserved Mosquitoes – Mosquito Museu
4. Imported Plants Could Deadly Harbor Mosquitoes, Says Report
5. Kids More Prone To Mosquito Bites
6. Mosquito Plague Reported From Western Australia
7. Minister Told To Rid State Of Mosquitoes
8. No Cure for the New Mosquito-Borne Disease, Chikungunya
9. Frog Secretions Could Be Used To Ward Off Mosquitoes
10. Chikungunya Fever: French Government struggling to Tackle the Mosquito Menace
11. Cyclone Glenda brings Threat of Fatal Mosquito–borne Diseas
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/26/2017)... ... July 26, 2017 , ... “We are thrilled to be partnering with ... to schedule an appointment online in real time,” said Keith English, LocalMed CEO. “Allowing ... directory will bring more Six Month Smiles patients to their providers.” , Each month, ...
(Date:7/26/2017)... ... July 26, 2017 , ... Isodiol ... global cannabis innovator, specializing in the development of pharmaceutical and consumer products, announces ... 2017 to June 30, 2017. Iso International LLC recorded unaudited fiscal Q1 profits ...
(Date:7/26/2017)... ... 26, 2017 , ... BioPlus Specialty Pharmacy (BioPlus), ... of the HCV Treatment Path app (version 4.4.0) to keep health care providers ... All of the latest HCV medications are included in this app, including Vosevi™ ...
(Date:7/25/2017)... , ... July 25, 2017 , ... Summers in Palm ... the air conditioner — think homemade gourmet ice cream, sparkling pools, and mile-high fun. ... shop featuring fun mugs, journals, and other must-have knick knacks. Ice cream and sorbet ...
(Date:7/25/2017)... ... July 25, 2017 , ... SureVest Insurance ... services to communities across North Carolina, is launching a charity event in conjunction ... support for the ongoing fight against bladder cancer. , The Bladder Cancer Advocacy ...
Breaking Medicine News(10 mins):
(Date:7/12/2017)... July 12, 2017  Eli Lilly and Company (NYSE: ... generic companies to resolve pending patent litigation in the U.S. ... regarding the Cialis ® (tadalafil) unit dose ... 26, 2020. As part of the agreement, Cialis exclusivity is ... 2018. "The unit dose patent for Cialis is ...
(Date:7/11/2017)... , July 11, 2017  Sysmex America, ... urinalysis diagnostic testing equipment as well as middleware ... a way to make quality assurance easier and ... "Sysmex is well known for the innovation that ... Quality Monitor elevates quality assurance processes to a ...
(Date:7/10/2017)... -- The Institute for In Vitro Sciences (IIVS), a ... a VITROCELL® inhalation exposure system thanks to a generous ... which is designed to replace animals in inhalation testing, ... airborne test materials in an environment that mimics the ... testing combustible tobacco products, as well as next generation ...
Breaking Medicine Technology: