Navigation Links
Malaria-resistant Mosquito Developed

Researchers have developed a malaria-resistant mosquito, a step that might one day help block the spread of an illness that has claimed millions// of lives around the world.

When they fed on malaria-infected mice, the resistant mosquitoes had a higher survival rate than nonresistant ones, meaning they could eventually replace the ones that can carry the disease, according to a report in Tuesday's issue of Proceedings of the National Academy of Sciences.

Jason Rasgon of the department of molecular microbiology and immunology at Johns Hopkins University cautioned that the research so far is only a proof of principle and any field tests remain far away.

Nonetheless, it's a goal eagerly sought by scientists in hope of developing a practical way of blocking the spread of malaria.

According to the federal Centers for Disease Control and Prevention, an estimated 700,000 to 2.7 million people die of malaria each year, 75 percent of them African children.

Working with the mouse form of malaria — not the human type — Rasgon's team was able to genetically engineer mosquitoes that were resistant to malaria.

Malaria infection does exact a toll on mosquitoes and in laboratory work they found that the resistant insects were able to compete nonresistant mosquitoes.

Starting with the same number of resistant and nonresistant mosquitoes, they found that after nine generations the resistant type made up 70 percent of the population — raising the possibility of replacing regular mosquitoes with resistant ones that don't spread disease.

However, Rasgon stressed that in the lab work the insects were infected with a higher amount of the parasite than occurs in nature, and a larger proportion of the mosquitoes were infected.

"This was proof of principle," Rasgon said in a telephone interview. "The next step would be to work in a system more epidemiologically relevant" but still in t he lab.

"We're not anywhere near a field release," he said. Now they need to turn their attention to working with human malaria and trying to engineer a mosquito resistant to that.

William C. Black IV, a professor of entomology at Colorado State University, noted that the work was done with Plasmodium berghei, which infects mice, rather than P. falciparum, which causes malaria in humans.

P. berghei is often used in laboratory work because it is easy to manipulate, but a lot of its properties are specific to that parasite and it is not always a good model for the human form, he said.

"On the other hand, finding a gene that confers resistance and is stable for a long period of time is significant," said Black, who was not part of the research team.

If they can repeat the work using the human parasite then there is a chance of taking it into the field, he said.

Dr. Woodbridge A. Foster, an entomologist at Ohio State University who was not part of the research team, said that while several labs have been trying to develop a resistant mosquito, he was not aware of any that had been developed that were both healthy and inhospitable to the malaria parasite.

Source-Bio-Bio Technology
SM
'"/>




Related medicine news :

1. Gene researchers make Malaria-resistant mosquito
2. Malaria To Be Tackled By Genetically Modified Mosquitoes
3. India Has The Oldest And Largest Collection Of Preserved Mosquitoes – Mosquito Museu
4. Imported Plants Could Deadly Harbor Mosquitoes, Says Report
5. Kids More Prone To Mosquito Bites
6. Mosquito Plague Reported From Western Australia
7. Minister Told To Rid State Of Mosquitoes
8. No Cure for the New Mosquito-Borne Disease, Chikungunya
9. Frog Secretions Could Be Used To Ward Off Mosquitoes
10. Chikungunya Fever: French Government struggling to Tackle the Mosquito Menace
11. Cyclone Glenda brings Threat of Fatal Mosquito–borne Diseas
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/26/2017)... ... May 26, 2017 , ... Amir Qureshi, MD is the first physician in ... cord stimulation system. The Nuvectra™ Algovita SCS System has been FDA approved as a ... first in Arkansas to introduce the most powerful SCS system and the only stretchable ...
(Date:5/26/2017)... Fla. (PRWEB) , ... May 26, 2017 , ... ... of premium delicatessen foods, is sharing bold recipes for Memorial Day entertaining that ... your menus. , “Boar’s Head fresh sliced meats and cheeses featured in ...
(Date:5/26/2017)... ... 26, 2017 , ... After raising nearly $30,000 on Kickstarter , about ... available at a discounted crowdfunding price on Indiegogo . , “Along with creating ... wanted to bring a fidget toy to the market that was made of superior ...
(Date:5/26/2017)... ... May 26, 2017 , ... Rob Lowe acts as host and ... the series is on hiking in American. Viewers can reconnect with America as it ... of hiking. , Many consumers have looked for an inventive new place for a ...
(Date:5/26/2017)... ... ... Cross”: the personal journey of Bob Massey and his faith in the Lord. “THE ... Massey. Bob Massey is small in stature but big in character. As Johnny ... others is apparent in all of his life decisions. , “I’m in the eightieth ...
Breaking Medicine News(10 mins):
(Date:5/10/2017)... -- Global Health Intelligence (GHI), the leading healthcare ... published its 2017 ranking of the Best-Equipped Hospitals in ... analysis from GHI,s hospitals database for Latin America , ... The GHI database covers 86% of the hospitals in ... points for each institution in key areas such as beds, ...
(Date:5/9/2017)... , May 9, 2017  Demonstrating its ... board of directors for the Pharmaceutical Research and ... for membership. Biopharmaceutical companies will now have to ... order to be eligible to join PhRMA. ... the board is sending a clear message that ...
(Date:5/6/2017)... Texas , May 5, 2017   Provista , ... with more than 200,000 customers, today announced Jim Cunniff ... a wealth of executive and business experience to Provista, including ... compounding pharmacy in California . He assumed ... "Jim is a great fit for Provista," says ...
Breaking Medicine Technology: