Navigation Links
Malaria infection can accelerate HIV infection and disease progression

Malaria and HIV infections are both of great public health importance in tropical countries. James Kublin and his colleagues have found that acute malaria episodes are associated with transient increases of HIV-1 viral load in the blood,// and they speculate that malaria episodes might accelerate HIV-1 disease progression and facilitate transmission.

Evidence is now emerging of the deleterious effects of HIV-1 infection on malaria. In pregnant women HIV-1 is associated with more peripheral and placental malaria, higher parasite densities, more fever, and increased risks of adverse birth outcomes. Researchers had previously worked on seven fold higher HIV-1 viral loads in adults with acute malaria compared with those without, and that this increase resolved over a few weeks after anti-malarial treatment.

35% of the study participants showed an increase in viral load tended to be greater with more severe episodes of malaria infection. Viral load is an important determinant of HIV-1 disease progression, but the average viral load increases reported in the study. Also, most of the increases were temporary, lasting less than 10 weeks, a short time in the context of an average disease course of 8-10 years.

There is evidence that many opportunistic infections are associated with immune activation and higher viral loads. HIV-1 transmission is reported to double for each log rise in viral load. Therefore the effects reported by the researchers might equate with about a 50% increase in transmission during the short period of higher viral load in blood.

Antiretroviral therapy and Co-trimoxazole prophylaxis, both of which might affect the attack rate and severity of malaria. Analyses of existing cohort studies of HIV in malaria prevalent areas would also yield useful information. Given the number of cases of HIV and malaria, even small increases in relative risks of HIV transmission and progression are important. The researcher’s findings are challenging and highlight the need for better integration of health services for HIV and malaria.

Source: Lancet
'"/>




Related medicine news :

1. Malaria strikes Munger tribals
2. Sponging Cattle betters spraying in eradicating Malaria
3. Gene researchers make Malaria-resistant mosquito
4. More Treatment Options For Malaria
5. Scientists Unveil Mechanism Behind Resistance to Severe Malaria
6. Jharkhand reports 13,000 Malaria cases
7. Researchers Discover Protein That Causes Malaria
8. Malarial gene ascertained
9. Artesunate Is Better For Malaria Than Quinine
10. New Strategies For Effective Treatment Of Malaria
11. Chloroquine and Primaquine combination Malarial drug for resistant parasites.
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/3/2016)... , ... May 03, 2016 , ... ... announced that it has been honored as one of the nation’s most accomplished ... InformationWeek Elite 100. Horizon received the recognition for technology achievements that have enabled ...
(Date:5/3/2016)... ... May 03, 2016 , ... BioPlus Specialty Pharmacy ... at the 2016 Asembia Specialty Pharmacy Summit held May 2-6, 2016 at the ... health care conference for the specialty pharmacy industry, with thousands of pharmacy providers, ...
(Date:5/3/2016)... ... May 03, 2016 , ... Empyrean Benefit Solutions, Inc., the ... service center in La Vergne, Tennessee, near Nashville. The new center will complement ... Empyrean client services. , “Our Nashville-area center allows us to achieve several goals,” ...
(Date:5/3/2016)... (PRWEB) , ... May 03, 2016 , ... Park Cities ... live in or adjacent to the 75204, 75205, 75206, 75209, 75219, 75220, 75225, 75229, ... Greenway Parks, Bluffview, Midway Hollow, North Dallas, Plano, Preston Hollow and Park Cities areas ...
(Date:5/3/2016)... , ... May 03, 2016 , ... ... one of Canada’s top Information and Communication Technology (ICT) companies in the annual ... Multinational ICT companies operating in Canada, as ranked by revenue. , “We ...
Breaking Medicine News(10 mins):
(Date:5/2/2016)... LAWRENCEVILLE, N.J. , May 2, 2016 /PRNewswire/ ... drug development company, today announced data from the ... dose escalating clinical trial (the OVATION Study) combining ... of care for the treatment of newly-diagnosed patients ... chemotherapy followed by interval debulking surgery.  In the ...
(Date:4/29/2016)... , April 29, 2016 ... H1 2016" market research report that provides an ... comparative analysis at various stages, therapeutics assessment by ... administration (RoA) and molecule type, along with latest ... also reviews key players involved in the therapeutic ...
(Date:4/29/2016)... Glycotope GmbH, a clinical-stage immuno-oncology ... appointment of Dr. Alfredo Zurlo as Chief ... with many years clinical experience and a proven track ... role was at Mologen AG where he was Chief ... Dr. Zurlo held various positions at F Hoffmann La ...
Breaking Medicine Technology: