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Malaria and HIV Jointly Affects Pregnant Women and Their Infants

gainst PAM. But HIV virus leads to the hammering of protection and makes them as vulnerable as first-time mothers.

To discover how HIV affects PAM, Kain and his team collected samples from women in the first pregnancy as well as from women in their subsequent ones living in the Kenyan region where malaria is widespread. The researchers demonstrated that protection to PAM is arbitrated by a unique type of antibody that allows women to preferentially clear the parasites in their placentas.

The results showed that HIV-infected women lose these antibodies and again become susceptible to the negative effects of PAM.

The findings, according to Kain, may help in the development of superior PAM vaccines.

"This is only the first step in creating therapeutics to treat this devastating disease. We hope to help translate this knowledge into more effective vaccines designed to generate these types of protective antibodies, Kain said.


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