Navigation Links
Malaria Can Develop In Lymph Nodes Also

The malaria parasites can develop in the lymph nodes also, according to a recent research, led by Robert Ménard. This reportedly has implications for the mammalian immune response. //

The dreaded disease is caused when a mosquito infected with Plasmodium bites a mammal, and the immature parasites travel to the animal's liver. Once they have fully developed, the parasites burst out of the liver cells and infect red blood cells, beginning the onset of malaria. After leaving the skin, the parasites frequently invaded blood vessels, as they need to travel through them to get to the liver.

However, scientists also found that many of the parasites also invaded lymphatic vessels, and about 25% of the parasites injected by the mosquito bites were drained by lymphatic vessels and ended up in lymph nodes close to the site of the bite.

The researchers found that though within about four hours of the mosquito bite, many of the lymph-node parasites appeared degraded, and were also seen interacting with key mammalian immune cells, suggesting that the immune cells were destroying them, a small number of the parasites in the lymph nodes escaped degradation and began to develop into forms usually found only in the liver.

Dr Ménard said that the development of malarial parasites in the lymph nodes may be a reason why the body was so tolerant to the parasites. The study showed that 52 hours after the mosquito bites, no parasites remained in the lymph nodes, thus suggesting that they cannot develop completely there. Dr Ménard said that as only fully developed parasites can infect red blood cells and cause malaria, the lymph-node parasites probably don't contribute to the appearance of malaria symptoms. However, they could still affect how the immune system responds to infection.

He further explained that parasites developing in the lymph nodes could have two opposite effects on the body's immune response. On one hand they might alert the body that an invader is present and activate a protective immune response, while on the other their presence in the lymph nodes might desensitize the body to the parasites, blunting the immune system's response to liver and blood cell infection.

Edited (ANI)
'"/>




Related medicine news :

1. Malaria strikes Munger tribals
2. Sponging Cattle betters spraying in eradicating Malaria
3. Gene researchers make Malaria-resistant mosquito
4. More Treatment Options For Malaria
5. Scientists Unveil Mechanism Behind Resistance to Severe Malaria
6. Jharkhand reports 13,000 Malaria cases
7. Researchers Discover Protein That Causes Malaria
8. Malarial gene ascertained
9. Artesunate Is Better For Malaria Than Quinine
10. New Strategies For Effective Treatment Of Malaria
11. Chloroquine and Primaquine combination Malarial drug for resistant parasites.
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/2/2016)... ... December 02, 2016 , ... Rijuven Corp launches rejiva ( http://www.rejiva.com ), a ... No other wearable health technology on the market can deliver all that rejiva can. ... meaningful insights about their health than the usual heart rate and steps taken”, adds ...
(Date:12/2/2016)... ... 02, 2016 , ... On November 24th, 2016, Thanksgiving morning, ... different sites throughout Miami-Dade and Broward counties. This is the largest meal delivery ... Thanksgiving morning by putting together individual meals via assembly lines and passing them ...
(Date:11/30/2016)... ... November 30, 2016 , ... ... that we have been designated as a Cigna Infertility Center of Excellence. The ... performance standards. , “It’s an honor to be designated a Cigna Infertility ...
(Date:11/30/2016)... Gardens, FL (PRWEB) , ... November 30, 2016 ... ... eating disorder and mental health treatment has announced the opening of a new ... specialized partial hospitalization and intensive outpatient treatment for adults and adolescents, both males ...
(Date:11/30/2016)... Austin, TX (PRWEB) , ... November 30, 2016 ... ... like to remind the clinical research community that the FDA Binding Guidance goes ... submit data in FDA-supported formats listed in the FDA Data Standards Catalog. The ...
Breaking Medicine News(10 mins):
(Date:12/2/2016)... 2, 2016 On Thursday, December ... excellence in research, development and innovation in the biopharmaceutical ... was held in the presence of Sergey Tsyb, Vice ... Russian Federation , Natalia Sanina, First Vice Chairman ... , Head of Roszdravnadzor, National Service of Control in ...
(Date:12/2/2016)... Dec. 2, 2016 CVS Health Corporation (NYSE: ... Day in New York City on Thursday, December 15, 2016, beginning at 8:00 ... team will provide an in-depth review of the company,s ... The company will also discuss 2017 earnings guidance during ... of the event will be broadcast simultaneously on the ...
(Date:12/2/2016)... YORK , December 2, 2016 ... the trading session in red, while the Dow Jones Industrial ... at the close of US markets, which prompted Stock-callers this ... stocks: NuVasive Inc. (NASDAQ: NUVA ), Smith & ... (NASDAQ: NXTM ), and Cesca Therapeutics Inc. (NASDAQ: ...
Breaking Medicine Technology: