Navigation Links
Major Hurdle towards Development of Bird Flu Vaccine in India.

Scientists at the High-Security Animal Disease Laboratory in Bhopal have finally helped to materialize India's dream of developing an effective poultry vaccine against// the deadly H5N1 bird flu virus last month. However, several obstacles lay in the path of finding a company to manufacture the vaccine.

This is because there is not a single Indian vaccine manufacturer who deals with influenza vaccines for poultry who has a Bio Safety Level (BSL) 3 lab, needed to house the live H5N1 bird flu virus to manufacture the vaccine.

The process of manufacturing the vaccine involves housing the live H5N1 virus first, isolating it, manufacturing it in bulk before killing it to make the vaccine.

Although scientists at the Bhopal lab, which is India's only BSL 4 lab for animal research, the highest level of bio-containment, has received offers from four vaccine manufacturers in the country, proposing the transfer of the technology, none of them has the required facility to cultivate the virus.

According to scientists the live virus, which is presently in their possession, cannot be transferred to a lab below BSL 3 status because the virus may slip into and mix with an open environment thereby creating havoc.

Lab chief H K Pradhan said, "Most of the companies have a Clean Room the ability to handle the virus after it is killed. However, none of them can house a live virus, which is an absolute necessity to develop this bird flu vaccine. No lab also has a containment system that can stop the virus from leaking out and mixing with the environment."

In a BSL 3 facility, design is a significant factor in safety because it involves organisms that pose a serious threat to humanity. These are usually constructed air tight with negative air pressure. BSL 3 labs require researchers to wear "moonsuits" inside air locked labs.

In addition the surfaces of all floors, walls and ceilings are sealed and, thereby , impervious to liquids. The ventilation system is designed to allow a directional airflow from the outer corridors, into the contaminated laboratory. Tests involving BSL 3 materials are performed in safety cabinets within the containment module.

The Indian scientists had developed the vaccine using the most potent strains of H5N1 virus that had hit the country in February. On June 16, Agriculture minister Sharad Pawar had announced that tests have shown this vaccine to provide 90% protection against the most virulent form of H5N1 virus.

Related medicine news :

1. First Artificial Heart patient has Major setback
2. Vision Loss Due To Diabetic Retinopathy a Major Cause Of Concern
3. Depression Found To Be A Major Cause for Death in Elderly
4. Genetics Has A Major Role To Play In Body Shape.
5. Pigs Population A Major Threat To Encephalitis Ravaged UP
6. Delhi Government To Interlink All Major Hospitals Through e-Governance
7. Nine Major Culprits For Tooth Loss Identified By Researchers
8. Obesity Among Children May Become a Major Problem
9. Canadian Lung Cancer Study Lauded As Major Advance in Cancer Fight
10. Smokers Sue Tobacco Major Philip Morris
11. India Can Become Major HIV Drugs Producer
Post Your Comments:

(Date:11/27/2015)... ... November 27, 2015 , ... Lizzie’s Lice Pickers just announced a ... customers 10% off of their purchase of lice treatment product. In addition, customers will ... to a company spokesperson. “Finding lice is a sure way to ruin the holidays, ...
(Date:11/27/2015)... ... November 27, 2015 , ... MPWH, the No.1 Herpes-only dating community in the world, revealed that ... ). More than 3.7 billion people under the age of 50 – or 67% ... WHO's first global estimates of HSV-1 infection . , "The data shocks us highly!" ...
(Date:11/27/2015)... ... 2015 , ... A simply groundbreaking television series, "Voices in America", which is ... an array of issues that are presently affecting Americans. Dedicated to providing the world ... is changing the subjects consumers focus on, one episode at a time. , ...
(Date:11/27/2015)... Los Angeles, CA (PRWEB) , ... November 27, 2015 , ... ... the Commission on Accreditation of Allied Health Education Programs (CAAHEP) awarded accreditation to its ... exclusive list of CAAHEP accredited colleges, as only one of twelve colleges and universities ...
(Date:11/27/2015)... ... November 27, 2015 , ... Avid collector, Andrew Hawley from ... boxing style concert posters. This is one of Joplin's most famous and beautiful concert ... the University of Michigan in Ann Arbor. The According to Hawley, "It is hard ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... 3D bioprinting market is expected ... new report by Grand View Research Inc. Rising prevalence of ... kidney transplantation is expected to boost the market growth, as ... transplantation. --> 3D bioprinting market is expected ... new report by Grand View Research Inc. Rising prevalence of ...
(Date:11/26/2015)... STOCKHOLM , November 26, 2015 /PRNewswire/ ... --> Juntendo universitetssjukhus ser potential att ... av magnetresonansbilder (MR-bilder) för patienter med ... tecknat ett forskningsavtal med SyntheticMR AB för ... kliniska forskningsprojekt på sjukhuset. Med SyMRI kan ...
(Date:11/26/2015)... , Nov. 26, 2015 Research and ... of the "2016 Future Horizons and Growth ... Market: Supplier Shares, Country Segment Forecasts, Competitive Intelligence, ... --> --> ... of the Italian therapeutic drug monitoring market, including ...
Breaking Medicine Technology: