Navigation Links
Major Hurdle towards Development of Bird Flu Vaccine in India.

Scientists at the High-Security Animal Disease Laboratory in Bhopal have finally helped to materialize India's dream of developing an effective poultry vaccine against// the deadly H5N1 bird flu virus last month. However, several obstacles lay in the path of finding a company to manufacture the vaccine.

This is because there is not a single Indian vaccine manufacturer who deals with influenza vaccines for poultry who has a Bio Safety Level (BSL) 3 lab, needed to house the live H5N1 bird flu virus to manufacture the vaccine.

The process of manufacturing the vaccine involves housing the live H5N1 virus first, isolating it, manufacturing it in bulk before killing it to make the vaccine.

Although scientists at the Bhopal lab, which is India's only BSL 4 lab for animal research, the highest level of bio-containment, has received offers from four vaccine manufacturers in the country, proposing the transfer of the technology, none of them has the required facility to cultivate the virus.

According to scientists the live virus, which is presently in their possession, cannot be transferred to a lab below BSL 3 status because the virus may slip into and mix with an open environment thereby creating havoc.

Lab chief H K Pradhan said, "Most of the companies have a Clean Room the ability to handle the virus after it is killed. However, none of them can house a live virus, which is an absolute necessity to develop this bird flu vaccine. No lab also has a containment system that can stop the virus from leaking out and mixing with the environment."

In a BSL 3 facility, design is a significant factor in safety because it involves organisms that pose a serious threat to humanity. These are usually constructed air tight with negative air pressure. BSL 3 labs require researchers to wear "moonsuits" inside air locked labs.

In addition the surfaces of all floors, walls and ceilings are sealed and, thereby , impervious to liquids. The ventilation system is designed to allow a directional airflow from the outer corridors, into the contaminated laboratory. Tests involving BSL 3 materials are performed in safety cabinets within the containment module.

The Indian scientists had developed the vaccine using the most potent strains of H5N1 virus that had hit the country in February. On June 16, Agriculture minister Sharad Pawar had announced that tests have shown this vaccine to provide 90% protection against the most virulent form of H5N1 virus.

Related medicine news :

1. First Artificial Heart patient has Major setback
2. Vision Loss Due To Diabetic Retinopathy a Major Cause Of Concern
3. Depression Found To Be A Major Cause for Death in Elderly
4. Genetics Has A Major Role To Play In Body Shape.
5. Pigs Population A Major Threat To Encephalitis Ravaged UP
6. Delhi Government To Interlink All Major Hospitals Through e-Governance
7. Nine Major Culprits For Tooth Loss Identified By Researchers
8. Obesity Among Children May Become a Major Problem
9. Canadian Lung Cancer Study Lauded As Major Advance in Cancer Fight
10. Smokers Sue Tobacco Major Philip Morris
11. India Can Become Major HIV Drugs Producer
Post Your Comments:

(Date:6/26/2016)... ... 26, 2016 , ... On June 10-11, 2016, A Forever Recovery, a holistic ... World’s Longest Breakfast Table in Battle Creek, MI, where the rehabilitation facility is located. ... some of the world’s leading providers of cereal and other breakfast foods. Its residents ...
(Date:6/26/2016)... ... June 26, 2016 , ... Brent Kasmer, a legally blind and certified personal trainer is ... a fitness app. The fitness app plans to fix the two major problems leading the ... one size fits all type program , They don’t eliminate all the reasons ...
(Date:6/25/2016)... ... ... Austin residents seeking Mohs surgery services, can now turn to Dr. Jessica ... Peckham for medical and surgical dermatology. , Dr. Dorsey brings specialization to include Mohs ... Mohs Micrographic Surgery completed by Dr. Dorsey was under the direction of Glenn Goldstein, ...
(Date:6/25/2016)... , ... June 25, 2016 , ... First Choice ... States, named Dr. Sesan Ogunleye, as the Medical Director of its new Mesquite-Samuell Farm ... Medical Director of our new Mesquite location,” said Dr. James M. Muzzarelli, Executive Medical ...
(Date:6/25/2016)... ... June 25, 2016 , ... On Friday, June 10, Van Mitchell, ... at Work award to iHire in recognition of their exemplary accomplishments in worksite health ... annual Maryland Workplace Health & Wellness Symposium at the BWI Marriott in Linthicum Heights. ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... 24, 2016  Arkis BioSciences, a leading innovator ... more durable cerebrospinal fluid treatments, today announced it ... funding is led by Innova Memphis, followed by ... private investors.  Arkis, new financing will accelerate the ... market release of its in-licensed Endexo® technology. ...
(Date:6/23/2016)... 23, 2016 Research and Markets has ... - Forecast to 2022" report to their offering. ... for the patients with kidney failure, it replaces the function ... the patient,s blood and thus the treatment helps to keep ... in balance. Increasing number of ESRD patients ...
(Date:6/23/2016)... , June 23, 2016 ... "Pharmaceutical Excipients Market by Type (Organic Chemical (Sugar, ... Formulation (Oral, Topical, Coating, Parenteral) - Global Forecast to ... The global pharmaceutical excipients market ... at a CAGR of 6.1% in the forecast period ...
Breaking Medicine Technology: