Navigation Links
MRI Detects Early Heart Damages In Patients

According to a study conducted by cardiologists of Duke University Medical Center, Magnetic Resonance Imaging (MRI) can be used as a conventional method for detecting heart// damages early in patients with the immune system disorder sarcoidosis, who are at higher risk of dieing from heart problems.

By using MRI to discover minute areas of heart damage before they grow larger, physicians may be able to take action to prevent sudden cardiac death, which is a leading cause of death in patients with sarcoidosis, the researchers said.

Sarcoidosis is characterized by the formation of tiny inflammatory growths called granulomas. Although granulomas tend to cluster in the lungs, in lymph nodes and under the skin, they also can form in the heart. When they do, it currently is difficult to determine which patients will develop heart damage, the researchers said.

"We found that MRI was sensitive in detecting small areas of damage in the hearts of patients with sarcoidosis, and we were further able to correlate these areas of damage with future adverse outcomes," said Duke cardiologist Manesh Patel, M.D., who presented the results of the study on Sunday, Nov. 12, at the annual scientific sessions of the American Heart Association, in Chicago. "The MRI technology is very good at obtaining high-resolution images of heart muscle and distinguishing normally functioning heart cells from those that are damaged or destroyed."

The Duke Cardiovascular Magnetic Resonance Center supported the study.

According to Patel, conventional methods identify cardiac damage in only 5 percent to 7 percent of sarcoidosis patients. The standard evaluation includes an electrocardiogram, which is an electrical test of the heart, coupled with one of a number of different cardiac imaging techniques.

But previous studies in which autopsies were performed on sarcoidosis patients indicate that up to 30 percent of such patients exhibit evidence of hea rt damage, he said.

"For this reason, we hypothesized that cardiac damage in sarcoidosis patients is more common and is often unrecognized, explaining why it could be a major cause of death in these patients," Patel said.

For their analysis, the Duke researchers identified 81 sarcoidosis patients consecutively referred for evaluation at Duke. All of the patients received a standard clinical evaluation including an electrocardiogram and on average 1.6 non-cardiac MRI imaging tests, and a cardiac MRI scan. The conventional method identified 10 patients (12.3 percent) with heart damage, while the cardiac MRI identified 21 patients (26 percent) with areas of heart damage, Patel said.

The damage observed often did not fit the pattern of damage caused by coronary artery disease, Patel said, a finding, which suggested that the sarcoidosis was the cause of the damage.

The patients in the study were followed by their treating physicians for an average of 13 months, and Patel's team examined their records to see if they had died or had experienced medical problems related to the heart's electrical system.

According to Patel, it is commonly thought that when sarcoidosis damages a portion of heart muscle, the damaged areas can block or reroute the electrical impulses that keep the heart beating. Sudden cardiac death can occur when the heart's internal electrical system is disrupted, causing the heart to beat erratically and, in some cases, to stop.

By the end of the follow-up period, five patients had died from cardiac causes, two had experienced heart-beat abnormalities requiring treatment to bring the heart back into normal rhythm and one needed a pacemaker implanted to maintain normal heart rhythm, Patel said.

The imaging technique that the team used is called delayed enhancement cardiac MRI. In this approach, the researchers inject trace amounts of the element gandolinium into patients before administerin g the MRI scan.

"Gandolinium is an inert metal, and it cannot enter normally functioning heart muscle cells," Patel said. "However, if small areas of heart muscle are damaged, there are areas that absorb the gandolinium like a sponge. The MRI then detects where the gandolinium accumulates and shows us where the damage is located."

Source-Eurekalert
SRI
'"/>




Related medicine news :

1. Helium And MRI Scanning Clearly Detects Smoker Lungs – Research Find
2. New Diagnostic Test Detects Avian Flu In Less Than 12 Hours
3. A Novel Technique That Detects "Cancer Genes" From The Breath Of Smokers
4. South Korea Detects Dioxin in U.S. Beef Consignment
5. Simple Test Detects Genetic Signs of Lung Cancer in a Patient’s Sputu
6. MR Angiography Detects Blocked Arteries Accurately
7. Early detection of prostate cancer
8. Early detection of heart attack
9. Early puberty linked to nutrition
10. Early Clue to Down Syndrome
11. Early delivery can prevent cancer
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/8/2016)... Ga (PRWEB) , ... December 08, 2016 , ... ... as soon after surgery as possible. With this in mind, SIGVARIS has created ... (DVT or blood clot) during bed rest and provide the benefits of graduated ...
(Date:12/8/2016)... ... December 08, 2016 , ... The ... from offices headquartered in Hamilton County, is embarking on a charity drive with ... in finding new homes for orphaned or neglected senior dogs in the Cincinnati ...
(Date:12/8/2016)... Louis, MS (PRWEB) , ... December 08, 2016 , ... ... that serve commercial and residential clients in and around the Hancock County area, is ... for the Hancock County Food Pantry. , The Hancock County Food Pantry has worked ...
(Date:12/7/2016)... ... December 07, 2016 , ... ... will have the unique opportunity to get hands-on experience in an emergency ... students an immersive experience to gain invaluable, real-life medical skills that are critical ...
(Date:12/7/2016)... ... December 07, 2016 , ... ... and deep lines by smoothing and tightening the skin of the face to ... to address facial aging with very little downtime, Silhouette Instalift is a novel, ...
Breaking Medicine News(10 mins):
(Date:12/8/2016)... 8, 2016 Australia Ophthalmic Lasers Market Outlook ... Ophthalmic Lasers Market Outlook to 2022", provides key market ... provides value, in millions of US dollars, volume (in ... Excimer Lasers, Femtosecond Lasers and YAG Lasers. The ... for each of these market segements, and global corporate-level ...
(Date:12/8/2016)... , Dec. 8, 2016 KEY FINDINGS ... poised to grow in 2017-2023. Various reasons for growth ... obese population, higher incidences of chronic diseases, high recovery ... mobility aid services. Medical lifting sling refers to ... with limited mobility. These slings connect to the lift ...
(Date:12/8/2016)... Dec 8, 2016 Research and Markets has announced the ... to their offering. ... This report analyzes the worldwide markets for Endodontic Supplies in ... Canada , Japan , Europe , ... of World. Annual estimates and forecasts are provided for the period ...
Breaking Medicine Technology: