Navigation Links
MIT Creates 3-D Scaffold for Growing Stem Cells

ttached to and supported by the cells, other structures and proteins around them. A cell's normal environment is a complex network of tiny fibers, gaps and pores through which oxygen, hormones and nutrients are delivered and waste products filtered away. Cells move within their natural environments in response to chemical signals or other stimuli.

Researchers are aware that cells on flat surfaces have skewed metabolisms, gene expression and growing patterns. But the only choices have been glass labware and a product called Matrigel, a gelatinous protein mixture secreted by mouse tumor cells. While Matrigel does resemble a complex extracellular environment, it also contains growth factors and unknown proteins that limit its desirability for experiments requiring precise conditions.

"Synthetic biopolymer microfiber scaffolds have been studied for more than 30 years to mimic a living 3D microenvironment, but concerns exist about their degradation products and chemicals," the authors wrote in the paper.

Other synthetic polymer biomaterials are simply too big. Getting cells to grow on them is like forcing spiders to build webs on skyscraper girders. Zhang's nanofiber scaffold, around 1,000 times smaller than the existing systems, is much closer in size to the extracellular matrices that living cells manufacture themselves.

Adding motifs

With the addition of defined amino acid fragments called active motifs, the scaffold can be fashioned to coax stem cells to behave in certain desirable ways-such as differentiating into needed body tissues or migrating toward bone marrow and other natural destinations.

"What makes these designer scaffolds particularly interesting is that cells survive longer and differentiate better without additional soluble growth factors," Zhang said. "This suggests that extracellular microenvironments may play a more important role for cell survival and for carrying out ce
'"/>




Page: 1 2 3

Related medicine news :

1. Experiment Creates Illusion Of Weight Loss
2. Death Of Woman Following Family Planning Operation Creates Panic
3. Measles Outbreak In Bihar Creates Panic
4. Suspected Bird Flu Death Creates Panic In Hong Kong
5. Male Students Entry in Womens College Creates Furore in Pakistan Assembly
6. Domino Transplants Creates new wave In the Field Of Kidney Transplantation
7. Dog’s Death During Demonstration Creates Uproa
8. AIIMS Creates Record by Completing 100 Four-arm Robotic Surgeries
9. UC Davis Creates New Nanoparticles
10. Autism Expert Creates Innovative Intervention Program
11. Californian Baby Creates History - Born from a Frozen Egg and Sperm
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: MIT Creates Scaffold for Growing Stem Cells

(Date:9/18/2014)... Ben Quirk, CEO of Quirk Healthcare ... Award by the Savannah Science Seminar in recognition for ... the nation and especially in Savannah. , “I am ... “The Savannah Science Seminar is an amazing program that ... have gone through the program,” he added. Eleventh graders ...
(Date:9/18/2014)... microbes -- don,t worry, it,s a good thing! As ... microbes are bad. Many active enzymes and bacteria are ... as an important part of our digestive system or ... albicans , an opportunistic yeast pathogen and model organism ... healthy personal ecosystem. However, when our immune system is ...
(Date:9/18/2014)... one-day conference at the Milken Institute School of Public ... 2014 to discuss the Global Health Security Agenda (GHSA) ... this event is to invite discussion of proposed priorities ... action plans to curtail the current deadly Ebola outbreak. ... organizations and more than 50 countries have engaged in ...
(Date:9/18/2014)... (September 18, 2014) The National Institutes of Health ... a four-year, $1.3 million grant to the Los Angeles ... research and development of a vaccine to protect patients ... Staphylococcus aureus (MRSA). , The National ... NIH awarded the grant to LA BioMed infectious disease ...
(Date:9/18/2014)... such as the Ebola virus invoke scary scenarios of ... bubonic plague are still providing researchers with new insights ... a study published online Sept. 18, 2014, in the ... Duke-NUS Graduate Medical School Singapore detail how the Yersinia ... cells in the lymph nodes and eventually ride into ...
Breaking Medicine News(10 mins):Health News:Quirk Awarded the Alex Ormond, Jr. Leadership Award by the Savannah Science Seminar 2Health News:Everything in moderation: Micro-8 to study regulating pathogens in space 2Health News:Everything in moderation: Micro-8 to study regulating pathogens in space 3Health News:Non-governmental stakeholders to discuss the Global Health Security Agenda 2Health News:LA BioMed receives NIH grant to study vaccine for hospital-acquired infections 2Health News:New insights on an ancient plague could improve treatments for infections 2
... ... follow-up. This study appears in Plastic and Reconstructive Surgery, the offical medical journal of the ... ... aesthetic procedures in the world for excess fat removal - and while its relative safety ...
... early intervention can help , MONDAY, March 1 (HealthDay ... between depression and obesity, say researchers who reviewed the ... , "We found bidirectional associations between depression and obesity: ... developing depression over time, whereas depressed persons had a ...
... ill with cancer from further pain prompts feelings, survey finds ... child die of cancer is unimaginably heartbreaking for parents, and ... terminally ill children from any further pain led one in ... from the Dana-Farber Cancer Institute in Boston asked 141 parents ...
... ... joined forces with Upside Group Franchise Consulting to expand their franchise base. ... retailer of conventional bedding and sleep related products. Upside Group Franchise ... the country. In the coming decade, the sleep industry is ...
... ... ... ... ...
... ... ... ... ...
Cached Medicine News:Health News:New Study Tunes Into Latest Lipo Technique 2Health News:Obesity and Depression: A Vicious Circle? 2Health News:Some Parents Consider Hastening a Sick Child's Death 2Health News:Some Parents Consider Hastening a Sick Child's Death 3Health News:Some Parents Consider Hastening a Sick Child's Death 4Health News:Mattress Firm Partners with Upside Group Franchise Consulting 2Health News:National Study Reports Staggering Spending Increases Among Seniors With Chronic Conditions Through Original Medicare - Special Needs Plan Program Offers Solution For Those In Texas 2Health News:National Study Reports Staggering Spending Increases Among Seniors With Chronic Conditions Through Original Medicare - Special Needs Plan Program Offers Solution For Those In Texas 3Health News:National Study Reports Staggering Spending Increases Among Seniors With Chronic Conditions Through Original Medicare - Special Needs Plan Program Offers Solution For Those In Texas 4Health News:Rhoads Named Director of Cancer Outreach Programs For Stanford Cancer Center, Cancer Prevention Institute of California 2Health News:Rhoads Named Director of Cancer Outreach Programs For Stanford Cancer Center, Cancer Prevention Institute of California 3Health News:Rhoads Named Director of Cancer Outreach Programs For Stanford Cancer Center, Cancer Prevention Institute of California 4Health News:Rhoads Named Director of Cancer Outreach Programs For Stanford Cancer Center, Cancer Prevention Institute of California 5Health News:Rhoads Named Director of Cancer Outreach Programs For Stanford Cancer Center, Cancer Prevention Institute of California 6
(Date:9/18/2014)... Pharma IQ, after huge demand ... Countdown calendar to cover the years 2014 - 2018 ... shows the serialisation requirements around the globe and the ... For companies dealing with international markets, serialisation ... they will have to comply with new regulations coming ...
(Date:9/18/2014)... 2014   3D Systems   (NYSE: DDD ... Mentor™ , a new robotic surgery skills and procedural training ... the ERUS exhibition in Amsterdam, The Netherlands ... Robotic-assisted minimally invasive surgery represents a growing portion of overall ... training for robotic surgery has increased, and it is expected ...
(Date:9/18/2014)... 2014 After 6 months of careful ... here - the new programme for the next Cool Chain ... our global Cool Chain series, has just been released! ... As the lines between supply chain, logistics, QA and ... that is broad and yet specific, focused and yet accessible, ...
Breaking Medicine Technology:Pharma IQ Displays Worldwide Serialisation Deadlines in their 2014 - 2018 Countdown Calendar 23D Systems Introduces New Simbionix Robotics Training Platform 23D Systems Introduces New Simbionix Robotics Training Platform 3Europe's Biggest and Longest-Running Gathering of Life Sciences Logistics, Supply Chain & QA Professionals 2
... , WASHINGTON, Nov. 24 ... and vaccines to treat or prevent HIV/AIDS and related conditions, according ... Manufacturers of America (PhRMA). December 1 marks the 21st anniversary of ... the 1988 World Summit of Ministers of Health on Programmes for ...
... , NORTH HOLLYWOOD, Calif., Nov. 24 ... national hospitalist physician group practice company, announced today that Philip Vaidyan, ... as one of the 2009 Top Ten Hospitalists in the ... magazine. , Dr. Vaidyan has been a practicing physician for more ...
Cached Medicine Technology:New Report Shows 97 Medicines and Vaccines Currently in Development for HIV/AIDS 2New Report Shows 97 Medicines and Vaccines Currently in Development for HIV/AIDS 3IPC The Hospitalist Company's Philip Vaidyan, M.D. Named a Top Hospitalist of 2009 2IPC The Hospitalist Company's Philip Vaidyan, M.D. Named a Top Hospitalist of 2009 3
For the qualitative detection of human Chorionic Gonadotrophin (HCG) in urine or urine and serum specimens...
ZyDoc offers a full medical transcription and documentation solution....
For the qualitative detection of single and multiple drugs and drug metabolites in human urine...
For the qualitative detection of single and multiple drugs and drug metabolites in human urine...
Medicine Products: