( s with ALL the most common form of chi...)Lymphocyte Count Found to Be a Predictor of Survival for Young Patients With Leukemia,Health

s with ALL, the most common form of childhood leukemia, researchers found that those children and young adults with a high ALC count on day 15 had an 87% six-year overall survival rate while those with a low lymphocyte count had a 55% overall survival rate.

Researchers at the Children's Cancer Hospital plan to continue their study by following newly diagnosed patients and have begun a new study that analyzes the subsets of lymphocytes to see which ones have the most impact on prognosis. They hope their findings will be used to help physicians worldwide make decisions on how aggressively to treat their patients.

"Many developing countries lack the latest technologies and treatment options that we have here in the United States," says senior author Patrick Zweidler-McKay, M.D., Ph.D., assistant professor of pediatrics. "A complete blood count test is a universal, inexpensive test. There is the potential for physicians worldwide to look at the ALC count to help determine whether the patient needs additional treatment options that aren't available in every center."

In addition to pediatric acute leukemias, these researchers have found that ALC predicts survival in young patients with non-Hodgkin's lymphoma and a bone cancer, Ewing's sarcoma. These findings suggest that this simple test, may redefine the way physicians treat a range of different cancers.


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