Navigation Links
Lung Cancer Drug effective in extending lives

An experimental drug discovered by researchers in New Zealand and developed by the UK biotechnology company, Antisoma, is found to be effective // in extending lives of lung cancer patients by one-third.

Doctors who welcome this breakthrough state that it is the first step in the fight against the disease. Lung cancer is one of the most deadly cancers and the death rate increases every year. The rate of survival over 5 years is only 5%. The efforts to bring down the death rate have failed in the past.

A study was conducted on 70 patients affected by non-small cell lung cancer. It was found that when they were treated with the drug, not yet named and known as AS1404, they lived for 14 months on an average whereas the patients treated with chemotherapy alone lived for 8.8 months.

Efforts to find an effective treatment have failed and unlike other cancers, such as breast cancer, the death rate has not changed for more than a decade. A trial of the as yet unnamed drug, known as AS1404, in 70 patients with non-small cell lung cancer (NSCLC), the commonest kind, found they lived for 14 months on average compared with 8.8 months for those given chemotherapy alone.

According to Antisoma, this 5.2 month difference is one of the biggest ever seen in a controlled trial conducted at random in which a new agent is given along with chemotherapy to treat lung cancer. In the trial, a reduction of 27% in the risk of death was observed among those treated with AS1404 when compared to those getting only chemotherapy.

Though the difference may seem insignificant, there is a sign of real benefits from the drug. The drug belongs to a new class of compounds called vascular disrupting agents. These agents damage the blood vessels supplying the solid tumors.

The victory of phase II trial has paved way for phase III study. The result of this study will decide the licensing of the drug as safe and effective. The efficacy of AS140 4 has already been proved in the phase II trials against prostate and ovarian cancer.

Mark McKeage of the University of Auckland, one of the researchers, said: "It is great to see this large survival benefit with AS1404 in lung cancer patients. This makes me feel very optimistic as we progress into phase III testing."

Professor Alex Markham, chief executive of Cancer Research UK, said: "Our drug development team played an integral role in the early development of the drug and we're delighted with this news. We look forward to seeing how the drug performs in a much larger number of patients." Over 100 agents have been put into trials since 1982. "Over the next five years we plan to double our activity and speed up the drug development process, getting even more new drugs into clinical trials," Professor Markham said.

Over 26,000 deaths are caused by NSCLC in Britain every year.
GYT
'"/>




Related medicine news :

1. Fibroids unlikely to Turn Cancerous
2. Virus Level could Predict Cervical Cancer Risk
3. Cancer Doctors Okays Controversial Prostate Therapy
4. Potential New Cancer Gene Identified
5. Consensus on "Combination Therapy" for Breast Cancer
6. Cancers of Colon & Rectum linked to Cigarette Smoking
7. Life Saving Cancer Drugs – From Chicken! Possible Says Dolly’ Creatos
8. The Cancer Rumour mill working over time
9. Cancer drugs in development nearly doubled since 1995
10. Radioactive Seeds used in Prostate Cancer treatment can migrate with the body
11. Cancer patients turning to Internet for information
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/26/2016)... ... May 26, 2016 , ... ... for the Foundation Fighting Blindness, Long Island Chapter on June 4, 2016, 1:30-3:30 ... , Dr. Maisel, founder of Retina Group of New York , is ...
(Date:5/26/2016)... , ... May 26, 2016 , ... In an effort to provide hair restoration information ... both Snapchat users and those who do not use the app. Dr. Mohebi, the founder ... page, Dr. Mohebi Live . , Dr. Mohebi says, “The positive response to ...
(Date:5/26/2016)... ... 26, 2016 , ... Leadership of Life Science Logistics (LSL), ... has earned its ISO 13485 certification, indicating the company’s quality control system for ... policies associated with ISO quality standard 13485. , BSI Group America, Inc., ...
(Date:5/26/2016)... ... 2016 , ... The Lung Institute has partnered with the Gulfcoast ... June 6 at their clinic in downtown Tampa. The class is complimentary for the ... has created a free downloadable 4 Week Smoking Cessation Guide for those ...
(Date:5/26/2016)... (PRWEB) , ... May 26, 2016 , ... ... offering campers a multitude of activities from daily practices, arts & crafts, discussions, ... Camp Directors Amber East-D’Anna and Christy Evans have combined backgrounds in kids’ yoga, ...
Breaking Medicine News(10 mins):
(Date:5/24/2016)... , May 24, 2016 Cirujanos ... para ayudar a los médicos a compartir sus mejores ... a escala mundial. Profesionales médicos de Europa, África, ... han apuntado a la aplicación, que combina la transmisión ... entorno totalmente seguro. Educación   "Imagine ...
(Date:5/24/2016)... 24, 2016 ARANZ Medical  Ltd ... healthcare sector, has been named the Coretex Hi-Tech Emerging Company ... Dr Bruce Davey , CEO of ARANZ ...  It,s really good to be recognised for the work we ... are used in 35 countries around the world from Sub-Saharan ...
(Date:5/24/2016)... KONG , May 24, 2016 ... , the world , s first ... AV fistula intervention   OrbusNeich, a global ... has expanded its portfolio to include products to treat ... are the company,s first entry devices for lower limb ...
Breaking Medicine Technology: