Navigation Links
Lowering Risk of Breast Cancer Recurrence

A new class of drugs could reduce the risk of breast cancer recurrence in post-menopausal women. Exemestane is a third-generation aromatase inhibitor. Aromatase inhibitors are drugs that block the conversion of precursor molecules. In the case of breast cancer, aromatase inhibitors block the conversion of precursor molecules into various types of estrogenic compounds. //In a new study, coordinated through the National Surgical Adjuvant Breast and Bowel Project, researchers are studying exemestane to determine if it can further reduce the risk of breast cancer recurrence among post-menopausal women.

John Cole, M.D., from the Ochsner Clinic in New Orleans, explains the ovaries in post-menopausal women no longer make estrogen. However, estrogen is still produced from the adrenal glands and from fatty tissues. He says by using an aromatase inhibitor like exemestane, that small residual amount of estrogen is even further reduced. Dr. Cole says, "You're taking low estrogen and you're making it even lower. Now, why does that matter? Well, breast cancer cells that are hormone-sensitive can sense even those very small amounts of estrogen."

Patients are still being enrolled in the trial. Researchers across the country will enroll 3,000 postmenopausal women who have received at least five years of tamoxifen therapy. Dr. Cole says, "Tamoxifen is a different type of medication. It blocks the receptors for estrogens on cancer cells." He says previous studies show aromatase inhibitors are at least equivalent, if not superior, to tamoxifen. He says, "It seems as though lowering the estrogen levels is even more effective than blocking estrogen interaction with cells in post-menopausal patients."

Dr. Cole says, even after five years of cancer-free status, there still is an ongoing risk of breast cancer recurrence. He says about 20 percent of patients in some groups will have recurrences after five years. He tells Ivanhoe that this is the first trial of thi s kind in this setting but says the results in terms of effectiveness are years away. "It will take a while before there is enough follow-up to be able to have enough recurrences to make a statement." He is optimistic about the efficacy of exemestane and says, "Our goal is to increase the number of patients who are cured from breast cancer by preventing a recurrence. Anything that prevents recurrences is going to increase cure."
'"/>




Related medicine news :

1. Lowering blood pressure beneficial for PAD patients
2. Multi-Drug Therapy Effective in Lowering Blood Pressure
3. Multi-Drug Therapy Found To Be More Effective in Lowering B.P
4. Almonds found To Be Effective In Lowering Cholesterol
5. Almonds As Effective As Certain Drugs In Lowering Cholesterol
6. Using Cholesterol Lowering Drugs Effectively
7. Lowering cholesterol with vegetables in your diet
8. Fibre Rich Food A Boon For Lowering Cholesterol
9. Dark Chocolate Is Helpful In Lowering Blood Pressure.
10. Plant – based Foods More Effective In Lowering Cholesterol
11. Plant – based Foods More Effective In Lowering Cholestero
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/24/2017)... ... April 24, 2017 , ... ... Bring Your Own Device (BYOD) capabilities at Telehealth 2.0, the American Telemedicine Association’s ... bundles, which pairs medical devices with a pre-programmed tablet in a remarkably easy-to-use ...
(Date:4/24/2017)... ... , ... Ridgecrest Herbals makes it a point to lead the Utah supplement ... support renewable energy. They believe this is a crucial part of their mission as ... issues, and maintain that destroying the environment in the pursuit of profit is unsustainable ...
(Date:4/24/2017)... ... 2017 , ... The bar for just about everything—apparel, eyewear, cars and even ... of pop and film stardom.(1) Not to be left out is that most desired ... run the gamut from being encrusted with jewels and precious metals to, at the ...
(Date:4/24/2017)... (PRWEB) , ... April 24, 2017 , ... Sean Fay ... Oxiclean, Space Bag, Sonicare Toothbrush, Juiceman Juicer, and the George Foreman Grill (which sold ... any other marketer in the last 25 years. , Now, due to changes in ...
(Date:4/24/2017)... ... April 24, 2017 , ... ALP Nutrition®, a ... announced its popular products are now available for purchase on StackedNutrition.com, a popular ... use of premium natural ingredients in making all of its products. These ingredients ...
Breaking Medicine News(10 mins):
(Date:4/19/2017)... MOUNTAIN VIEW, Calif. , April 19, 2017 /PRNewswire/ ... that it will release financial results for the first ... May 3, 2017.  The Company,s management team will host ... / 5:30 p.m. ET. Investors interested in ... dialing (844) 707-0665 for domestic callers or (703) 326-3030 ...
(Date:4/19/2017)... NASHVILLE , Tenn. and DALLAS , ... and EndoStim, Inc., announced that the first patients in ... with the EndoStim device in the Lower Esophageal Sphincter ... is a minimally-invasive implantable device designed to provide long-term ... through neurostimulation. GERD affects nearly 65 million ...
(Date:4/19/2017)... April 19, 2017 ... immune response in pets such as canine, avian ... of various types such as Attenuated Live Vaccines, ... DNA Vaccines and Recombinant Vaccines. Attenuated live vaccines ... or bacteria, which have been weakend under laboratory ...
Breaking Medicine Technology: