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Low Levels of Testosterone may Increase the Risk of Death in Older Men

d and is associated with chronic diseases of aging."

The National Institute on Aging and the American Heart Association funded the study.

The Rancho Bernardo Study

Dr. Elizabeth Barrett-Connor is founder and director of the Rancho Bernardo Heart and Chronic Disease Study, now in its 35th year. Since 1972, the RB study has greatly increased knowledge of cardiovascular disease, diabetes, cancer, osteoporosis, exogenous and endogenous hormones, and the connections between lifestyle, behavior and health. Six thousand residents, 82 percent of the original population of adults in Rancho Bernardo, agreed to participate in this history-making study and significant collection of data.
Barrett-Connor and a team of UCSD researchers have conducted clinical research visits with the participants every four years for more than three decades. The clinical research visits last three to four hours, thoroughly examining the participants physical condition by gathering information through bone and heart scans, blood samples, heart disease risk factor measurements such as lipid levels and cognitive function assessment. The rate of follow-up with those who have moved or died (through cooperation of family and friends), has been exceptionally high.

A Living Legacy

The RB study has just been re-funded for what Barrett-Connor predicts will be the final clinic visit. Another newly funded grant from the National Institutes of Health (NIH) will allow analysis of information gathered over the course of the study to provide new insights on the link between heart disease risk and cognitive function.

"Although more than 400 scientific papers based on RB data have already been published, its a wonderful legacy for participants to realize that the knowledge gathered has not come close to being exhausted. Its an enormous bank of data," said Laughlin. "Though we are beginning the final visits with the RB g
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