Navigation Links
Low LDL Levels Lead to Parkinson's Disease

Researchers at University of North Carolina at Chapel Hill suggested that low LDL values can increase the incidence of Parkinson’s disease.//

LDL stands for low density lipoprotein; the low values of LDL are associated with good cardiovascular status. Previously associations have been made between LDL and cardiovascular diseases, smoking and Parkinson’s Disease.

"People with Parkinson's disease have a lower occurrence of heart attack and stroke than people who do not have the disease," said Dr. Xuemei Huang, medical director of the Movement Disorder Clinic at UNC Hospitals and an assistant professor of neurology in the UNC School of Medicine. "Parkinson's patients are also more likely to carry the gene APOE-2, which is linked with lower LDL cholesterol." And for more than a decade, researchers have known that smoking, which increases a person's risk for cardiovascular disease, is also associated with a decreased risk of Parkinson's disease.

These findings led Huang to examine whether higher LDL cholesterol might be associated with a decreased occurrence for Parkinson's disease, and vice versa. "If my hypothesis was correct," she said, "lower LDL-C, something that is linked to healthy hearts, would be associated with a higher occurrence of Parkinson's." The results of Huang's study, published online Dec. 18 by the journal Movement Disorders, confirmed her hypothesis. "We found that lower LDL concentrations were indeed associated with a higher occurrence of Parkinson's disease," Huang said. Participants with lower LDL levels (less than 114 milligrams per deciliter) had a 3.5-fold higher occurrence of Parkinson's than the participants with higher LDL levels (more than 138 milligrams per deciliter).

Huang cautioned that people should not change their eating habits, nor their use of statins and other cholesterol-lowering drugs, because of the results. The study was based on relatively small numbers of cases and controls, and the results are too preliminary, she said. Further large prospective studies are needed, Huang added.

"Parkinson's is a disease full of paradoxes," Huang said. "We've known for years that smoking reduces the risk of developing Parkinson's. More than 40 studies have documented that fact. But we don't advise people to smoke because of the other more serious health risks," she said.

Huang and her colleagues recruited 124 Parkinson's patients who were treated at the UNC Movement Disorder Clinic between July 2002 and November 2004 to take part in the study. Another 112 people, all spouses of patients treated in the clinic, were recruited as the control group. Fasting cholesterol profiles were obtained from each participant. The researchers also recorded information on each participant's gender, age, smoking habits and use of cholesterol-lowering drugs.

Huang notes that the study also found participants with Parkinson's were much less likely to take cholesterol-lowering drugs than participants in the control group. This, combined with the findings about LDL cholesterol, suggests two questions for additional study, Huang said.

"One is whether lower cholesterol predates the onset of Parkinson's. Number two, what is the role of statins in that? In other words, does taking cholesterol-lowering drugs somehow protect against Parkinson's? We need to address these questions," she said.

Source-Eurekalert
KO
'"/>




Related medicine news :

1. Levels Of Blood Proteins May Help Heart Disease Care
2. Elevated Ozone Levels Hurt Sperm Count
3. Elevating Manganese Levels hold back HIV
4. High Levels of Protein Linked to Brain Shrinkage
5. Chickens Found To Have High Levels of Arsenic
6. Low Protein Levels A Possible Indicator For A Miscarriage
7. Low Testosterone Levels the Cause Of Depression In Men
8. Weather Found To Play An Important Role In Cholesterol Levels
9. Education Levels Found To Predict Stress
10. Effective Control Of Blood Sugar Levels
11. Elevated Blood Sugar Levels A Risk Factor Of Heart Disease
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/27/2016)... Dublin, CA (PRWEB) , ... June 27, 2016 ... ... Community College District , the only authorized OSHA Training Institute Education Center headquartered ... illness by protecting their workers from extreme heat at their worksites. Employers ...
(Date:6/27/2016)... ... June 27, 2016 , ... "FCPX editors can now reveal their media ... Pro X," said Christina Austin - CEO of Pixel Film Studios. , ProSlice ... X users can now reveal the media of their split screens with growing ...
(Date:6/27/2016)... ... , ... TherapySites, the leading website and online ... Counseling Association. This new relationship allows TherapySites to continue to extend their ... benefits and promotional offers. , "TCA is extremely excited about this new partnership, ...
(Date:6/27/2016)... ... June 27, 2016 , ... ... today announced its strategic partnership with Connance, a healthcare industry leader providing ... companies’ proven, proprietary technology combine to provide health systems, hospitals and ambulatory ...
(Date:6/27/2016)... NY (PRWEB) , ... June 27, 2016 , ... ... using cutting edge technology to revolutionize the emergency ambulance transport experience for the ... are aware of how Uber has disrupted the taxi industry through the use ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... 2016   Bay Area Lyme Foundation , ... Center for Tick Borne Illness , Harvard Medical ... Hacking Medicine, University of California, Berkeley, and the ... five finalists of Lyme Innovation , the ... 100 scientists, clinicians, researchers, entrepreneurs, and investors from ...
(Date:6/24/2016)... Mass. and SAN CLEMENTE, Calif. , ... California -based mobile pulmonary function testing company, is now able ... PFT devices developed by ndd Medical Technologies , Inc. ... testing done in hospital-based labs.  Thanks to ndd,s EasyOne PRO ® ... , can get any needed testing done in the comfort ...
(Date:6/24/2016)... 24, 2016  Arkis BioSciences, a leading innovator ... more durable cerebrospinal fluid treatments, today announced it ... funding is led by Innova Memphis, followed by ... private investors.  Arkis, new financing will accelerate the ... market release of its in-licensed Endexo® technology. ...
Breaking Medicine Technology: