Navigation Links
Low Doses Of Arsenic Have Broad Impact On Hormone Activity – Says A Researc

Dartmouth Medical School investigators are learning more about how low doses of arsenic, such as the levels found in drinking water in many areas of the United States//, affect human physiology. In a paper published online on Dec. 2 in the journal Chemical Research in Toxicology, the researchers report that three different steroid hormones all show similar responses to arsenic, suggesting a broader effect and a common mechanism of arsenic on how these hormones function.

"Since most of the health consequences of exposure to arsenic - various cancers, diabetes, heart and vascular disease, reproductive and developmental effects, etc. - involve these same steroid receptors, we think that disruption of their normal function could explain, in large part, how arsenic can influence so many disease risks," says Joshua Hamilton, one of the authors on this study and the director of the Center for Environmental Health Sciences at Dartmouth and Dartmouth's Superfund Basic Research Program on Toxic Metals.

Hamilton's laboratory had earlier found that arsenic disrupts the activity of the glucocorticoid receptor, and this follow up study considered the progesterone and mineralocorticoid receptors, which regulate a wide range of biological processes. This work was done in collaboration with Jack Bodwell, the lead author on this paper and a research associate professor of physiology at Dartmouth Medical School.

Hamilton, Bodwell, and their team found that arsenic appears to suppress the ability of all three of these critical receptors to respond to their normal hormone signals. Chemicals that disrupt steroid hormone receptor signaling are called endocrine disruptors, and this study provides further evidence that arsenic, a metal, does not behave like other endocrine disruptors such as pesticides.

"Arsenic does not activate these receptors, as some endocrine disruptors do, by mimicking the natural hormone, nor does it block the ability of the n
'"/>




Page: 1 2 3

Related medicine news :

1. India To Procure 1 Million Doses Of Tamiflu
2. Small Doses Of Radiation Can Help Certain Lung Cancer Patients
3. Polyphenols in Green Tea Cause Liver Damage At High Doses
4. Pre-eclampsia Pronounced With Intake of Vitamins in Large Doses
5. Stronger Doses Fewer Administration for Breast Cancer
6. High Doses Of Common Pain killers Can Double The Chances Of Heart attack
7. Even Normal Doses Of Tylenol Could Damage Liver
8. Allergic Individuals Should Carry Two Doses Of EpiPen Says Quebec Coroner
9. Reduced Doses of Medication Beneficial to Preschoolers with ADHD
10. Low Doses of Anti-Depressant May Help PMS
11. High Doses of Lithium-Like Drugs May Impair Neuronal Function
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Low Doses Arsenic Have Broad Impact Hormone Activity Says Researc

(Date:4/18/2014)... have been awarded two-year grants for their work on ... Of the 110 initial submissions to the new Novo ... four projects were funded, three of which are led ... Ph.D.; G. William Wong, Ph.D.; and Elias Zambidis, M.D., ... will use his $500,000 proof of principle grant to ...
(Date:4/18/2014)... psychologists have made a brain-related discovery that could ... , This discovery opens up the possibility that ... a specific brain activity that the researchers have ... Journal of Neuroscience has just published ... an associate professor of psychology and his doctoral ...
(Date:4/18/2014)... by Northwestern Medicine scientists could lead to potential new ... people with scleroderma. , Fibrosis, or scarring, is ... the skin and lungs can lead to serious organ ... for new therapeutic options centers on findings made by ... identified the role that a specific protein plays in ...
(Date:4/17/2014)... identified the first genetic variant specifically associated with ... for around 10-15 per cent of all breast ... the breast cancer sub-type, called invasive lobular carcinoma, ... of this particular kind of breast cancer, which ... published today (Thursday) in the journal PloS ...
(Date:4/17/2014)... According to a study published today in PLOS ... world where malaria is common can mount an immune ... them to avoid repeated bouts of high fever and ... in their bloodstream. The findings may help researchers develop ... by the malaria parasite. , Each year, approximately 200 ...
Breaking Medicine News(10 mins):Health News:Scientists discover brain's anti-distraction system 2Health News:New clues on tissue scarring in scleroderma 2Health News:First genetic link discovered to difficult-to-diagnose breast cancer sub-type 2Health News:First genetic link discovered to difficult-to-diagnose breast cancer sub-type 3Health News:Study sheds light on how the immune system protects children from malaria 2
... A new study by physician researchers from Hasbro Children,s ... prevalence in left-handedness in children with a congenital disorder ... in the March 2009 edition of the Journal ... of the population is left-handed. A higher frequency has ...
... Care today announced that it is one of only ... by the Society of Chest Pain Centers (SCPC). With ... Resurrection physicians deliver specialized care during the critical early ... effective, and educate and monitor patients to ensure that ...
... March 2 "President Obama,s appointment of Governor Kathleen ... is yet another clear signal that this is the ... a reality.Health care reform is crucial to fixing the ... Health and Human Services, we can be sure it ...
... Snack Bars Now Available at Atkins.com and in Stores ... its market-leading, weight-management products, announced that your favorite Atkins(TM) ... those bars voluntarily recalled in the nationwide recall. ... atkins.com and will be in retail stores across ...
... Calif., March 2 The deadliest wildfires in the ... and injured many more. Local medical institutions are filled ... severe burns. The United States, largest tissue bank, the ... by providing skin to treat some of those victims ...
... your broccoli: UCLA researchers report that a naturally occurring ... help protect against respiratory inflammation that causes conditions like ... , Published in the March edition of ... that sulforaphane, a chemical in broccoli, triggers an increase ...
Cached Medicine News:Health News:New study finds increased prevalence of left-handedness in children with facial development disorder 2Health News:Resurrection Health Care Hospitals Receive Chest Pain Accreditation 2Health News:Kathleen Sebelius Ready to Lead Healthcare Reform in 2009 2Health News:Attention Snackers: Your Favorite Peanut Butter Bars Are Back! 2Health News:MTF, Largest Tissue Bank, Provides Skin for Victims of Australian Wildfires 2Health News:Broccoli may help protect against respiratory conditions like asthma 2
(Date:1/15/2014)... Jan. 15, 2014 MultiCell Technologies, Inc. (OTC Bulletin ... provisional patent application concerning composition of matter, biological targets, ... tumor cell death.  This patent application ... stranded RNA molecules (VSRNAs) which interfere with the basic ...
(Date:1/15/2014)... 2014 Reportlinker.com announces that a new ... catalogue: Insulin Pump ... http://www.reportlinker.com/p01957812/Insulin-Pump-Market--Forecast-–-Worldwide-Analysis.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Medical_Equipment_and_Supply ... Insulin Pumps are gaining strong acceptance ...
(Date:1/15/2014)... NEW YORK , Jan. 15, ... new market research report is available ... Global Markets and Technologies for ... on Routes of Administration ...
Breaking Medicine Technology:MultiCell Technologies Files Patent Application Covering New Class of RNA Therapeutics 2MultiCell Technologies Files Patent Application Covering New Class of RNA Therapeutics 3Insulin Pump Market & Forecast - Worldwide Analysis 2Insulin Pump Market & Forecast - Worldwide Analysis 3Insulin Pump Market & Forecast - Worldwide Analysis 4Insulin Pump Market & Forecast - Worldwide Analysis 5Insulin Pump Market & Forecast - Worldwide Analysis 6Insulin Pump Market & Forecast - Worldwide Analysis 7Insulin Pump Market & Forecast - Worldwide Analysis 8Insulin Pump Market & Forecast - Worldwide Analysis 9Insulin Pump Market & Forecast - Worldwide Analysis 10Insulin Pump Market & Forecast - Worldwide Analysis 11Insulin Pump Market & Forecast - Worldwide Analysis 12Insulin Pump Market & Forecast - Worldwide Analysis 13Insulin Pump Market & Forecast - Worldwide Analysis 14Insulin Pump Market & Forecast - Worldwide Analysis 15Insulin Pump Market & Forecast - Worldwide Analysis 16Insulin Pump Market & Forecast - Worldwide Analysis 17Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 2Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 3Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 4Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 5Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 6Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 7Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 8Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 9Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 10Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 11Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 12Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 13Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 14Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 15Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 16
Rigid rake retractor, 3 blunt prongs....
Econo lucae bayonet forceps....
Medpor 2/3 Orbit implants are designed to replace non load bearing bony structures in the orbital area....
... Inferior Orbital Rim implant can provide up ... designed to be trimmed to meet the ... flange allows it to rest on the ... This flange allows easier positioning of the ...
Medicine Products: