Navigation Links
Low-Dose Oral Contraceptives May Increase Risk For Heart Attack Or Stroke

Women taking low-dose oral contraceptives maybe at increased risk of heart attack// or stroke as per a recent study. However the risk disappears if they stop the pill.

The study done at Virginia Commonwealth University is published in the July issue of the Journal of Clinical Endocrinology and Metabolism. The findings could have further significance for those women taking low-dose oral contraceptives who already are at increased risk for such events because of polycystic ovary syndrome, or metabolic disorder, according to John Nestler, M.D., professor and chair of the Division of Endocrinology and Metabolism in the VCU School of Medicine.

In the study, researchers reported that the overall estimated risk of cardiovascular events – both heart attack and stroke -- among current low-dose oral contraceptive users was doubled compared to non-users.

The findings are based on a meta-analysis of peer-reviewed literature. . The analysis included studies published between January 1980 and October 2002.

"The study suggests that women in general are at an increased risk of having a cardiovascular event while taking even these third-generation, low-dose, birth control pills," said Nestler.

"Prolonged exposure to low-dose oral contraceptives in a population at higher risk may significantly increase the incidence of cardiovascular outcomes and prompt consideration of alternative therapeutic or contraceptive interventions," he wrote.

"A number of women with metabolic syndrome or polycystic ovary syndrome already are at increased risk for heart attack, and a majority of women with PCOS are treated with low-dose oral contraceptives for a prolonged period of time," he said. "An insulin-sensitizing drug might confer better general health benefits than the oral contraceptive."

"For example, insulin-sensitizing drugs have been shown to decrease progression to Type 2 diabetes, and there is evidence sugges ting that they also may lower the risk of cardiovascular disease and have beneficial effects on cardiovascular risk factors," he said.

Polycystic ovary disease is a condition that can affect a woman's menstrual cycle, fertility, hormones, insulin production, heart, blood vessels and appearance.

"Despite the doubling of risk associated with the pill, the absolute risk for a cardiovascular event in an individual woman taking the pill is low … Women using the pill are not going to automatically have a heart attack," said Nestler. "However, our findings do raise the issue of whether oral contraceptives are optimal therapy for certain groups of women who are at baseline risk or who are taking the pill for a longer time, such as women with PCOS."

According to Nestler, previous epidemiological studies have shown an increased risk of cardiovascular events associated with oral contraceptives in women with hypertension, migraines, or who smoke.

The research was supported by a grant from the National Institutes of Health and the Fond de Recherche en Santé du Québec.

Contact: Malorie Janis
mgjanis@vcu.edu
804-827-0889
Virginia Commonwealth University

'"/>




Related medicine news :

1. Low-Dose Hormones Help the Bones
2. FDA To Reconsider Standards for Reviewing Low-Dose Oral Contraceptives
3. Low-Dose Steroids Reduce Joint Damage From Rheumatoid Arthritis
4. Contraceptives via Internet
5. Contraceptives decreases Libido
6. Contraceptives have dual effects
7. Drugs For Anthrax May Interfere With Oral Contraceptives
8. Smoking and Oral Contraceptives:
9. Prevent Multiple Sclerosis From Oral Contraceptives
10. Usage Of Oral Contraceptives Need Not Be Feared By SLE Patients
11. Contraceptives to get some reprieve from VAT in UK
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/28/2017)... , ... April 28, 2017 , ... ... been previously exposed to more adverse experiences than children in the general population. ... such as abuse, neglect or other family challenges. While no fault of their ...
(Date:4/28/2017)... ... April 28, 2017 , ... Early detection and elimination ... safety and minimize the cost of development. In this webinar, sponsored by Molecular ... lines and for cardiac toxicity using induced pluripotent stem cells (iPSCs). , In ...
(Date:4/28/2017)... ... April 28, 2017 , ... Yisrayl Hawkins, Pastor and Overseer at The House of Yahweh in ... responds to and which He does not. Yisrayl says with so many titles and ... true name, but he says with a little Scripture, backed with a lot of research, ...
(Date:4/28/2017)... ... April 28, 2017 , ... Intellitec Solutions announced the ... implement a Microsoft Dynamics GP solution that integrates to their PointClickCare EHR software ... in long-term care, Brooke Grove now has the capability to achieve its goal ...
(Date:4/28/2017)... , ... April 28, 2017 , ... Rob Lowe is ... now he has leant his presence to an educational purpose as the host of ... important one being cancer. In a recent episode, the series focuses on thyroid cancer. ...
Breaking Medicine News(10 mins):
(Date:4/20/2017)... 20, 2017 Research and Markets has ... Manufacturing Services Market Analysis By Service (Manufacturing, Research), By Country, ... - 2025" report to their offering. ... The Latin American pharmaceutical contract manufacturing ... 2025 Low drug registration cost in Latin American ...
(Date:4/19/2017)... 19, 2017 The Mobile X-Ray product segment is ... CAGR during the forecast period Mobile X-Ray segment ... digital mobile X-Ray devices market, which is estimated to be ... at a CAGR of 7% over the forecast period. Mobile ... more than US$ 100 Mn in 2017 over 2016. The ...
(Date:4/19/2017)... YORK , April 19, 2017 ... This report on the prostate cancer therapeutics ... the global market. Increasing prevalence of prostate cancer, ... innovation in the development of new drugs & ... prostate cancer drug due to lesser side effects ...
Breaking Medicine Technology: