Navigation Links
Low-Dose Oral Contraceptives May Increase Risk For Heart Attack Or Stroke

Women taking low-dose oral contraceptives maybe at increased risk of heart attack// or stroke as per a recent study. However the risk disappears if they stop the pill.

The study done at Virginia Commonwealth University is published in the July issue of the Journal of Clinical Endocrinology and Metabolism. The findings could have further significance for those women taking low-dose oral contraceptives who already are at increased risk for such events because of polycystic ovary syndrome, or metabolic disorder, according to John Nestler, M.D., professor and chair of the Division of Endocrinology and Metabolism in the VCU School of Medicine.

In the study, researchers reported that the overall estimated risk of cardiovascular events – both heart attack and stroke -- among current low-dose oral contraceptive users was doubled compared to non-users.

The findings are based on a meta-analysis of peer-reviewed literature. . The analysis included studies published between January 1980 and October 2002.

"The study suggests that women in general are at an increased risk of having a cardiovascular event while taking even these third-generation, low-dose, birth control pills," said Nestler.

"Prolonged exposure to low-dose oral contraceptives in a population at higher risk may significantly increase the incidence of cardiovascular outcomes and prompt consideration of alternative therapeutic or contraceptive interventions," he wrote.

"A number of women with metabolic syndrome or polycystic ovary syndrome already are at increased risk for heart attack, and a majority of women with PCOS are treated with low-dose oral contraceptives for a prolonged period of time," he said. "An insulin-sensitizing drug might confer better general health benefits than the oral contraceptive."

"For example, insulin-sensitizing drugs have been shown to decrease progression to Type 2 diabetes, and there is evidence sugges ting that they also may lower the risk of cardiovascular disease and have beneficial effects on cardiovascular risk factors," he said.

Polycystic ovary disease is a condition that can affect a woman's menstrual cycle, fertility, hormones, insulin production, heart, blood vessels and appearance.

"Despite the doubling of risk associated with the pill, the absolute risk for a cardiovascular event in an individual woman taking the pill is low … Women using the pill are not going to automatically have a heart attack," said Nestler. "However, our findings do raise the issue of whether oral contraceptives are optimal therapy for certain groups of women who are at baseline risk or who are taking the pill for a longer time, such as women with PCOS."

According to Nestler, previous epidemiological studies have shown an increased risk of cardiovascular events associated with oral contraceptives in women with hypertension, migraines, or who smoke.

The research was supported by a grant from the National Institutes of Health and the Fond de Recherche en Santé du Québec.

Contact: Malorie Janis
mgjanis@vcu.edu
804-827-0889
Virginia Commonwealth University

'"/>




Related medicine news :

1. Low-Dose Hormones Help the Bones
2. FDA To Reconsider Standards for Reviewing Low-Dose Oral Contraceptives
3. Low-Dose Steroids Reduce Joint Damage From Rheumatoid Arthritis
4. Contraceptives via Internet
5. Contraceptives decreases Libido
6. Contraceptives have dual effects
7. Drugs For Anthrax May Interfere With Oral Contraceptives
8. Smoking and Oral Contraceptives:
9. Prevent Multiple Sclerosis From Oral Contraceptives
10. Usage Of Oral Contraceptives Need Not Be Feared By SLE Patients
11. Contraceptives to get some reprieve from VAT in UK
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/24/2016)... ... June 24, 2016 , ... Those who have experienced ... feelings, many turn to unhealthy avenues, such as drug or alcohol abuse, as a ... has released tools for healthy coping following a traumatic event. , Trauma sufferers tend ...
(Date:6/24/2016)... ... ... Marcy was in a crisis. Her son James, eight, was out of control. Prone to ... , “When something upset him, he couldn’t control his emotions,” remembers Marcy. “If there ... my other children and say he was going to kill them. If we were ...
(Date:6/24/2016)... ... June 24, 2016 , ... Global law firm Greenberg Traurig, P.A. announced ... attorneys chosen by their peers for this recognition are considered among the top 2 ... received special honors as members of this year’s Legal Elite Hall of Fame: ...
(Date:6/24/2016)... CA (PRWEB) , ... June 24, 2016 , ... Comfort ... the American Cancer Society and the Road To Recovery® program to drive cancer patients ... seniors and other adults to ensure the highest quality of life and ongoing independence. ...
(Date:6/24/2016)... Plano, TX (PRWEB) , ... June 24, 2016 , ... ... taking part in Genome magazine’s Code Talker Award, an essay contest in which patients ... for an award to be presented at the 2016 National Society of Genetic Counselors ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... -- Research and Markets has announced the addition ... 2022" report to their offering. ... with kidney failure, it replaces the function of kidneys by ... and thus the treatment helps to keep the patient body,s ... Increasing number of ESRD patients & substantial healthcare ...
(Date:6/23/2016)... -- Roche (SIX: RO, ROG; OTCQX: RHHBY) announced that ... PCT (procalcitonin) assay as a dedicated testing solution for ... clearance, Roche is the first IVD company in the ... risk assessment and management. PCT is a ... in blood can aid clinicians in assessing the risk ...
(Date:6/23/2016)... Bracket , a leading clinical trial technology and specialty ... Bracket eCOA (SM) 6.0, at the 52 nd ... in Philadelphia , Pennsylvania.  A demonstration of ... its kind to fully integrate with RTSM, will be held ... a flexible platform for electronic clinical outcomes assessments that is ...
Breaking Medicine Technology: