Navigation Links
Longer Needles Best for Infant Immunisation

Infants vaccinated with a long needle experience fewer reactions but get the same protection (immunogenicity) as a shorter needle, finds a study published on bmj.com// today.

In the UK, primary care practitioners administer infant immunisations at 2, 3 and 4 months of age. Despite recommendations for use of a wide-long (23G, 25mm) needle, many UK practitioners immunise infants using a narrow-short (25G, 16mm) needle and uncertainty has arisen because of insufficient data to define best practice.

In a previous study, researchers from Oxford found that the wider-longer needle significantly reduced local reactions at 4 months of age. However, they did not know whether this was due to difference in needle length or gauge, or whether needle size affected vaccine immunogenicity.

To answer these questions, they carried out another trial comparing three needle sizes varying in length and diameter.

696 infants were randomly immunised with either a wide-long (23G, 25mm); a narrow-short (25G, 16mm); or a narrow-long (25G, 25mm) needle at 2, 3 and 4 months. Parents recorded local and general reactions for 3 days following each dose and antibody concentrations were measured 28-42 days after the third dose.

Local reactions decreased significantly with wider-longer over narrower-shorter needles.

Significantly fewer infants vaccinated with the longer needle experienced severe local reactions. Immunogenicity following injection with the longer needle was, however, comparable to that achieved with the shorter needle.

Comparisons between the same length, different gauge needles showed little difference in local reaction or immune response suggesting that needle length, rather than gauge, is responsible.

The results show a clear benefit of using the longer needle at each dose whilst achieving comparable immunogenicity, say the authors. They suggest that vaccine manufacturers and national pol icymakers use this evidence in recommendations for infant immunisation.

With increasing parental attention focused on the safety rather than the efficacy of vaccines, simple interventions, such as the use of a longer needle, that reduce local reactions should be welcomed, they conclude.


'"/>




Related medicine news :

1. Longer airway in males increases sleep disorder risk
2. Longer Lung Cancer Survival
3. Patients Are Given Catheter Longer Than Necessary
4. Fat Patients Require Longer Needles
5. Patients In Ontario Wait Longer For Treatment
6. Quality Platelets and Improved Blood Availability No Longer a Pipe Dream
7. Oscar Winners Live Longer Than Co-Competitors
8. Threat from Chikungunya, No Longer a Fear
9. Cyber Sex, No Longer A Fantasy Of The Mind
10. Kids Face a Slim Chance of Growing Obese, If Breastfed Longer Than Three Months
11. Misleading Health Claims On Food Labels No Longer Allowed in EU
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... Worth, TX (PRWEB) , ... October 13, 2017 ... ... financial planning agency serving communities in the greater Dallas, Miami, and Raleigh regions, ... young boy fighting to overcome a rare and deadly chromosome abnormality. , After ...
(Date:10/13/2017)... , ... October 13, 2017 , ... The American Board ... become its next President and Chief Executive Officer, succeeding Dr. James C. Puffer upon ... beginning July 1, 2018 until Dr. Puffer’s retirement at the end of 2018. Upon ...
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... Lori R. ... a member of ElderCounsel, a national organization of elder law and special needs planning ... laws and rules. It also provides a forum to network with elder law attorneys ...
(Date:10/13/2017)... NY (PRWEB) , ... October 13, 2017 , ... Ellevate ... people in business to advocate for action towards gender equality at their inaugural Summit ... from around the globe, and reached a social audience of over 3 million. To ...
(Date:10/13/2017)... ... 2017 , ... Coveros, a leader in agile coaching services ... by the Center for Medicare and Medicaid Services (CMS). The Enterprise Agile Transformation ... Agile methodologies in a consistent and high value manner across CMS programs. Coveros ...
Breaking Medicine News(10 mins):
(Date:10/2/2017)... COPENHAGEN, Denmark , Oct. 2, 2017 The ... tool in the struggle to reverse the tide of prescription ... plan for regulating their medicine intake and stepping down their ... is set to launch in December 2017; the first 100,000 ... access. Learn more at http://www.rebound-solution.com/ ...
(Date:9/25/2017)... Sept. 25, 2017   Montrium , an ... solutions, today—from the IQPC Trial Master Files & ... NL)—announced that EastHORN Clinical Services has selected ... and TMF management. EastHORN, a leading European contract ... to increase transparency to enable greater collaboration with ...
(Date:9/19/2017)... medical device company developing a non-invasive, robotically assisted, platform therapy that uses pulsed sound energy ... ... Jim Bertolina, PhD ... Tom Tefft ... executive Josh Stopek , PhD, who has led R&D and business development teams at ...
Breaking Medicine Technology: