Navigation Links
Long-time Gastric Acid Suppression Does Not Increase The Risk Of Cancer

The use of H2 blocker drugs such as ranitidine (Zantac) and cimetidine (Tagamet)and proton pump inhibitors like omeprazole //(Prilosec) reduce stomach acid. This was believed to increase the risk of cancer of the esophagus or stomach.

However, a new finding says that H2 blockers and proton pump inhibitors do not increase the risk of such cancers. The cancer risk is probably due to other related factors. 'There have been concerns regarding the safety of long-time gastric acid suppression,' senior investigator Dr Mats Lindblad said.'I think our large study clearly suggests that long-time gastric acid suppression does not increase the risk of cancer of the esophagus or stomach'.

Lindblad and his colleagues at the Karolinska Institute in Stockholm studied 7 years of patient data gathered in the UK general practice database.

287 patients with esophageal cancer and 522 with stomach cancer were identified. They were compared with 10,000 randomly selected subjects who were not affected by cancer.

The authors identified specific conditions for which acid-suppressing drugs are used, such as acid reflux disease, hiatal hernia and Barrett's esophagusand which were associated with an increased risk of stomach and esophagus cancer. They found no evidence to show that the drugs themselves increased the risk. No cancer risk was seen with other conditions, including peptic ulcer, gastritis, and indigestion.

'These findings are similar to results from previous studies', continued Lindblad. The inference is that the cancer risk may be due to underlying conditions, and not an independent, harmful effect of these drugs. In an interview, Dr Kenneth E L McColl, author of an accompanying editorial, agreed with him. McColl of the Western Infirmary, Glasgow, UK says that 'a major weakness in the study is the relatively short duration of acid suppressive therapy examined. The development of cancer in humans is a slow proce ss.'

The period in question 'is really too short to identify or exclude any direct effect between acid suppressive medication and stomach or esophageal cancers'


ASH
'"/>




Related medicine news :

1. The Reason For Loss Of Appetite After Gastric Bypass
2. Gastric bypass surgery reduces risk of heart disease
3. Surgeons Perform Robotic Gastric Bypass Surgery
4. Helicobacter pylori Antibiotic Treatment of Peptic Ulcer May not Prevent Gastric lymphomas
5. New Gastric Cancer Drug Unlikely to Benefit Kidney Cancer Patients
6. Migraine Patients Suffer From Gastric Stasis
7. Gastric Bypass And Laparoscopic Reflux Surgery Gaining Popularity
8. Gastric bypass can cause deficiency of Vitamin A
9. For Super-Obese Patients, Duodenal Switch Beats Gastric Bypass
10. Gastric Bypass Surgery May Lead to Increased Kidney Stone Risk
11. Robotically Assisted Colo-resection And Gastric Bypass Surgeries Are Becoming Popular
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... 13, 2017 , ... Talented host, actor Rob Lowe, is ... a new episode of "Success Files," which is an award-winning educational program broadcasted ... each subject in-depth with passion and integrity. , Sciatica occurs when the sciatic ...
(Date:10/13/2017)... ... October 13, 2017 , ... “America On The Brink”: the Christian ... On The Brink” is the creation of published author, William Nowers. Captain Nowers ... a WWII veteran, he spent thirty years in the Navy. Following his career ...
(Date:10/12/2017)... , ... October 12, 2017 , ... Planet Fitness, one ... U.S., announced today its plans to open a flagship location in Covington, LA at ... former Rooms To Go store next to Office Depot in the Holiday Square shopping ...
(Date:10/12/2017)... ... 2017 , ... The American College of Medical Informatics (ACMI) will present the ... Opening Session of AMIA’s Annual Symposium in Washington, D.C. AMIA’s Annual Symposium ... a pioneer in the field of medical informatics, this prestigious award is presented to ...
(Date:10/12/2017)... ... October 12, 2017 , ... Dr. Parsa Mohebi, the ... medical article to the newly revamped Cosmetic Town journal section, featuring ... transplant procedure known as Follicular Unit Extraction (FUE). , Dr. Mohebi ...
Breaking Medicine News(10 mins):
(Date:10/11/2017)... 2017  True Health, a leader in integrated ... during National Breast Cancer Awareness month to educate ... Research recently published ... more than 10 million American women are at ... or BRCA2 and have not had testing. These mutations ...
(Date:10/7/2017)... , Oct. 6, 2017   Provista, a ... than $100 billion in purchasing power, today announced a ... information. The Newsroom is the online home ... trends, infographics, expert bios, news releases, slideshows and events. ... to a wealth of resources at their fingertips, viewers ...
(Date:10/4/2017)... Oct. 4, 2017 OBP Medical ... illuminating medical devices, today announced regulatory approval from ... Agency (or Agência Nacional de Vigilância Sanitária (ANVISA)) ... cordless surgical retractor with integrated LED light source ... illumination and exposure of a tissue pocket or ...
Breaking Medicine Technology: