Navigation Links
Long-time Gastric Acid Suppression Does Not Increase The Risk Of Cancer

The use of H2 blocker drugs such as ranitidine (Zantac) and cimetidine (Tagamet)and proton pump inhibitors like omeprazole //(Prilosec) reduce stomach acid. This was believed to increase the risk of cancer of the esophagus or stomach.

However, a new finding says that H2 blockers and proton pump inhibitors do not increase the risk of such cancers. The cancer risk is probably due to other related factors. 'There have been concerns regarding the safety of long-time gastric acid suppression,' senior investigator Dr Mats Lindblad said.'I think our large study clearly suggests that long-time gastric acid suppression does not increase the risk of cancer of the esophagus or stomach'.

Lindblad and his colleagues at the Karolinska Institute in Stockholm studied 7 years of patient data gathered in the UK general practice database.

287 patients with esophageal cancer and 522 with stomach cancer were identified. They were compared with 10,000 randomly selected subjects who were not affected by cancer.

The authors identified specific conditions for which acid-suppressing drugs are used, such as acid reflux disease, hiatal hernia and Barrett's esophagusand which were associated with an increased risk of stomach and esophagus cancer. They found no evidence to show that the drugs themselves increased the risk. No cancer risk was seen with other conditions, including peptic ulcer, gastritis, and indigestion.

'These findings are similar to results from previous studies', continued Lindblad. The inference is that the cancer risk may be due to underlying conditions, and not an independent, harmful effect of these drugs. In an interview, Dr Kenneth E L McColl, author of an accompanying editorial, agreed with him. McColl of the Western Infirmary, Glasgow, UK says that 'a major weakness in the study is the relatively short duration of acid suppressive therapy examined. The development of cancer in humans is a slow proce ss.'

The period in question 'is really too short to identify or exclude any direct effect between acid suppressive medication and stomach or esophageal cancers'


ASH
'"/>




Related medicine news :

1. The Reason For Loss Of Appetite After Gastric Bypass
2. Gastric bypass surgery reduces risk of heart disease
3. Surgeons Perform Robotic Gastric Bypass Surgery
4. Helicobacter pylori Antibiotic Treatment of Peptic Ulcer May not Prevent Gastric lymphomas
5. New Gastric Cancer Drug Unlikely to Benefit Kidney Cancer Patients
6. Migraine Patients Suffer From Gastric Stasis
7. Gastric Bypass And Laparoscopic Reflux Surgery Gaining Popularity
8. Gastric bypass can cause deficiency of Vitamin A
9. For Super-Obese Patients, Duodenal Switch Beats Gastric Bypass
10. Gastric Bypass Surgery May Lead to Increased Kidney Stone Risk
11. Robotically Assisted Colo-resection And Gastric Bypass Surgeries Are Becoming Popular
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/25/2016)... ... June 25, 2016 , ... ... non-athletes recover from injury. Recently, he has implemented orthobiologic procedures as a method ... —Johnson is one of the first doctors to perform the treatment. Orthobiologics are ...
(Date:6/24/2016)... , ... June 24, 2016 , ... Those who have ... these feelings, many turn to unhealthy avenues, such as drug or alcohol abuse, as ... Michigan, has released tools for healthy coping following a traumatic event. , Trauma sufferers ...
(Date:6/24/2016)... ... ... Global law firm Greenberg Traurig, P.A. announced that 20 Florida attorneys are ... for this recognition are considered among the top 2 percent of lawyers practicing within ... of this year’s Legal Elite Hall of Fame: Miami Shareholders Mark D. Bloom, ...
(Date:6/24/2016)... ... 24, 2016 , ... People across the U.S. are sharpening their pencils and ... essay contest in which patients and their families pay tribute to a genetic counselor ... National Society of Genetic Counselors (NSGC) Annual Education Conference (AEC) this September. , ...
(Date:6/24/2016)... ... June 24, 2016 , ... Strategic Capital ... area economy by obtaining investment capital for emerging technology companies. SCP has ... have already resulted in more than a million dollars of capital investment for ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... 2016 Research and Markets has announced ... report to their offering. ... a favourable commercial environment for MedImmune to enter. The US ... will serve to drive considerable growth for effective anti-influenza medications. ... cap sales considerably, but development is still in its infancy. ...
(Date:6/23/2016)... and INDIANAPOLIS , June 23, ... a Lilly Diabetes Tomorrow,s Leaders Scholarship is any indication, ... winners, announced today online at www.diabetesscholars.org by ... 1 diabetes stand in the way of academic and ... the Foundation,s scholarship program since 2012, and continues to ...
(Date:6/23/2016)...  Guerbet announced today that it has been named ... . One of 12 suppliers to receive ... support of Premier members through exceptional local customer service ... to lower costs. ... outstanding customer service from Premier," says Massimo Carrara ...
Breaking Medicine Technology: