Navigation Links
Long-time Gastric Acid Suppression Does Not Increase The Risk Of Cancer

The use of H2 blocker drugs such as ranitidine (Zantac) and cimetidine (Tagamet)and proton pump inhibitors like omeprazole //(Prilosec) reduce stomach acid. This was believed to increase the risk of cancer of the esophagus or stomach.

However, a new finding says that H2 blockers and proton pump inhibitors do not increase the risk of such cancers. The cancer risk is probably due to other related factors. 'There have been concerns regarding the safety of long-time gastric acid suppression,' senior investigator Dr Mats Lindblad said.'I think our large study clearly suggests that long-time gastric acid suppression does not increase the risk of cancer of the esophagus or stomach'.

Lindblad and his colleagues at the Karolinska Institute in Stockholm studied 7 years of patient data gathered in the UK general practice database.

287 patients with esophageal cancer and 522 with stomach cancer were identified. They were compared with 10,000 randomly selected subjects who were not affected by cancer.

The authors identified specific conditions for which acid-suppressing drugs are used, such as acid reflux disease, hiatal hernia and Barrett's esophagusand which were associated with an increased risk of stomach and esophagus cancer. They found no evidence to show that the drugs themselves increased the risk. No cancer risk was seen with other conditions, including peptic ulcer, gastritis, and indigestion.

'These findings are similar to results from previous studies', continued Lindblad. The inference is that the cancer risk may be due to underlying conditions, and not an independent, harmful effect of these drugs. In an interview, Dr Kenneth E L McColl, author of an accompanying editorial, agreed with him. McColl of the Western Infirmary, Glasgow, UK says that 'a major weakness in the study is the relatively short duration of acid suppressive therapy examined. The development of cancer in humans is a slow proce ss.'

The period in question 'is really too short to identify or exclude any direct effect between acid suppressive medication and stomach or esophageal cancers'


ASH
'"/>




Related medicine news :

1. The Reason For Loss Of Appetite After Gastric Bypass
2. Gastric bypass surgery reduces risk of heart disease
3. Surgeons Perform Robotic Gastric Bypass Surgery
4. Helicobacter pylori Antibiotic Treatment of Peptic Ulcer May not Prevent Gastric lymphomas
5. New Gastric Cancer Drug Unlikely to Benefit Kidney Cancer Patients
6. Migraine Patients Suffer From Gastric Stasis
7. Gastric Bypass And Laparoscopic Reflux Surgery Gaining Popularity
8. Gastric bypass can cause deficiency of Vitamin A
9. For Super-Obese Patients, Duodenal Switch Beats Gastric Bypass
10. Gastric Bypass Surgery May Lead to Increased Kidney Stone Risk
11. Robotically Assisted Colo-resection And Gastric Bypass Surgeries Are Becoming Popular
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/9/2016)... ... February 09, 2016 , ... Center for Autism ... diagnosed with autism spectrum disorder (ASD). Beginning Jan. 1, 2016, Medicaid is covering ... analysis (ABA) is key to providing effective treatment for individuals with ASD. Now, ...
(Date:2/9/2016)... ... February 09, 2016 , ... A ... fee schedule rates and Medicare rates for a variety of medical services in ... Evaluation of the 2015 Fee Schedule Rates in Illinois, are professional ...
(Date:2/9/2016)... ... 2016 , ... Establishment Labs, a global breast implant and medical technology company, ... of Directors. , “We are honored to welcome David to our Board ... Jose Chacon Quiros, CEO of Establishment Labs. "David’s knowledge and experience will be invaluable ...
(Date:2/9/2016)... ... 2016 , ... Dr. Rassouli, cosmetic dentist in Orange County , is ... popular cosmetic procedures in dentistry today, but the cost often leads to patients looking ... of teeth whitening-related damage. For a limited time, Dr. Rassouli is offering this special ...
(Date:2/9/2016)... ... February 09, 2016 , ... Two renowned photographers, Robert Caplin ... photographic adventure on the island, June 14-19, 2016, hosted by Four Seasons Resort Maui ... , After a successful debut in 2015, the Maui Photo Expedition workshop ...
Breaking Medicine News(10 mins):
(Date:2/9/2016)... Mass. , Feb. 9, 2016   AllCare ... The Joint Commission,s Gold Seal of Approval ® ... compliance with its performance standards. The Gold Seal of ... reflects an organization,s commitment to providing safe and effective ... AllCare Plus Pharmacy underwent a rigorous on-site survey ...
(Date:2/9/2016)... 2016 The leader in accelerated orthodontics, OrthoAccel ... is the recipient of the 2015 Townie Choice Award ... II medical device that speeds up orthodontic tooth movement ... often associated with treatment, AcceleDent was selected by orthodontists ... Orthotown survey of the most reliable and ...
(Date:2/9/2016)... Feb. 9, 2016  Johnson & Johnson (NYSE: ... Global Healthcare Conference on Tuesday, Feb. 23, at the ... Caruso , Vice President, Finance & Chief Financial Officer ... represent the Company in a session scheduled at 10:00 ... --> www.investor.jnj.com . --> This webcast ...
Breaking Medicine Technology: