Navigation Links
Link between Old Cells and Ageing probed

How much do we know about the connection between age factor and ageing cells? Now, Brown university biologists have found new proof that might establish this connection between old cells and old bodies. //

During a study of baboons, it was discovered that as the baboons aged, their skin showed an increased presence of old cells. It is well known that, as we age, the cells capability to divide, dwindles. This state is termed as replicative senescence. This novel research is the first of its kind that places a finger on the presence of such replicatively senescent cells, published in an advanced online edition of science.

According to John Sedivy, a professor of Medical Science at Brown University and a senior scientist in this project, whether old cells contribute to body aging is a highly controversial topic, prompting the skeptics to question this finding. Although, the initial evidence clearly rests in the recent finding, more needs to be known about how cells multiply anywhere from 60 to90 times prior to the onset of senescence, known to protect the body against disease. Old cells still do their job though not with as much vigor as the young cells and hence the reason for all those wrinkles, slackened healing, cancer and an infirm immune system. There is proof that these senescent cells are not benign, but not enough evidence that their numbers are present in large numbers in aged animals.

This marked the beginning of a study by Brown’s team which involved Baboons from the research preserve aged between 5 and 30 comparable to human age from 15 to 90. Skin samples were extracted from the monkey’s forearms. They were further tested by scientists in the sedivy lab for the presence of six bio markers, which mean the onset of cellular aging. The most important indicator for replicative senescence is telomere dysfunction that stops the division of cells. Infact, scientists did the hair splitting task of counting the cells with bio markers. T heir finding revealed that the number of senescent cells increased with advancing age, with cells present in 5 yr olds being as less as 4% compared to a high of 20% in 30 yr olds. Of course this is just the tip of the iceberg; further studies are required to probe deep into the subject.

Utz Herbig ,Brown post-doctoral research fellow is the lead author of the article. Mark Ferreira, Brown undergraduate, Laura Condel and Dee Carey from the Southwest Foundation for Biomedical Research have made noteworthy contributions. This work has been funded by the National Institute on Ageing.


'"/>




Related medicine news :

1. CDC reveals relationship between prepregnant weight and heart defects in infants
2. Link between Constipation and Parkinsons Disease
3. Is there a link between bones and memory?
4. Comparison between warfarin and aspirin
5. No link between blood groups and prostate cancer
6. Link between chlorine byproducts and pregnancy risks
7. No link between bad weather and rheumatism
8. No connection between breast cancer and pill
9. No connection between epidurals and backache
10. Link between birth weight and Insulin Resistance
11. Link between athleticism and neurological disease
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/28/2017)... Santa Monica, CA (PRWEB) , ... March 28, ... ... expert, Dr. Carson Liu of SkyLex Advanced Surgical, Inc. is thrilled to offer ... newest gastric balloon procedure, and this procedure adds to SkyLex Advanced Surgical’s ...
(Date:3/28/2017)... ... March 28, 2017 , ... The Lice Treatment Center® ... March 13-16, was a busy spot this year. Liz Solovay and Adrian Picheny, ... preventing outbreaks among camp communities during the upcoming 2017 camping season. “Lice infestations ...
(Date:3/28/2017)... ... ... Silicon Valley Hair Institute, the San Francisco Bay Area leader in women's ... loss. Although hair transplant procedures can be seen as more of a man’s issue, ... two reasons a woman may see her hair thinning. , “We are used to ...
(Date:3/28/2017)... ... , ... Thank you to all who attended Capio Partners Winter 2017 Healthcare ... exclusive to providers and offered an opportunity to collaborate and network with healthcare colleagues ... Hyatt where attendees gathered for a lively discussion on trends and issues that healthcare ...
(Date:3/28/2017)... ... 28, 2017 , ... “A Prophets Bones”: a thrilling adventure that reveals the mystery of Kevin’s ... things that his parents and teachers had asked of him that he had neglected to ... to defy the Almighty Creator. There were some who would have felt themselves to be ...
Breaking Medicine News(10 mins):
(Date:3/28/2017)... , March 28, 2017  Medeon Biodesign, Inc., ... company, is pleased to announce that the Company ... of Panther Orthopedics, Inc., a San ... fixation solutions for orthopedic extremity applications.  ... expand rapidly, primarily due to procedure volume growth, ...
(Date:3/27/2017)... 2017 Summary This report ... Lilly and its partnering interests and activities since 2010. ... an in-depth insight into the partnering activity of one of ... company reports are prepared upon purchase to ensure inclusion of ... The report will be delivered in PDF format within ...
(Date:3/27/2017)... IRVINE, Calif. , March 27, 2017  Cryoport, ... announced that it intends to offer shares of common ... shelf registration statement on file with the Securities and ... market and other conditions, and there can be no ... be completed, or as to the actual size or ...
Breaking Medicine Technology: