Navigation Links
Link between Old Cells and Ageing probed

How much do we know about the connection between age factor and ageing cells? Now, Brown university biologists have found new proof that might establish this connection between old cells and old bodies. //

During a study of baboons, it was discovered that as the baboons aged, their skin showed an increased presence of old cells. It is well known that, as we age, the cells capability to divide, dwindles. This state is termed as replicative senescence. This novel research is the first of its kind that places a finger on the presence of such replicatively senescent cells, published in an advanced online edition of science.

According to John Sedivy, a professor of Medical Science at Brown University and a senior scientist in this project, whether old cells contribute to body aging is a highly controversial topic, prompting the skeptics to question this finding. Although, the initial evidence clearly rests in the recent finding, more needs to be known about how cells multiply anywhere from 60 to90 times prior to the onset of senescence, known to protect the body against disease. Old cells still do their job though not with as much vigor as the young cells and hence the reason for all those wrinkles, slackened healing, cancer and an infirm immune system. There is proof that these senescent cells are not benign, but not enough evidence that their numbers are present in large numbers in aged animals.

This marked the beginning of a study by Brown’s team which involved Baboons from the research preserve aged between 5 and 30 comparable to human age from 15 to 90. Skin samples were extracted from the monkey’s forearms. They were further tested by scientists in the sedivy lab for the presence of six bio markers, which mean the onset of cellular aging. The most important indicator for replicative senescence is telomere dysfunction that stops the division of cells. Infact, scientists did the hair splitting task of counting the cells with bio markers. T heir finding revealed that the number of senescent cells increased with advancing age, with cells present in 5 yr olds being as less as 4% compared to a high of 20% in 30 yr olds. Of course this is just the tip of the iceberg; further studies are required to probe deep into the subject.

Utz Herbig ,Brown post-doctoral research fellow is the lead author of the article. Mark Ferreira, Brown undergraduate, Laura Condel and Dee Carey from the Southwest Foundation for Biomedical Research have made noteworthy contributions. This work has been funded by the National Institute on Ageing.


Related medicine news :

1. CDC reveals relationship between prepregnant weight and heart defects in infants
2. Link between Constipation and Parkinsons Disease
3. Is there a link between bones and memory?
4. Comparison between warfarin and aspirin
5. No link between blood groups and prostate cancer
6. Link between chlorine byproducts and pregnancy risks
7. No link between bad weather and rheumatism
8. No connection between breast cancer and pill
9. No connection between epidurals and backache
10. Link between birth weight and Insulin Resistance
11. Link between athleticism and neurological disease
Post Your Comments:

(Date:11/27/2015)... ... November 27, 2015 , ... The moment you stop ... not only fulfilling the needs of advisers and clients but going above and ... providing top-tier customer service. However, there's always room for improvement, which is why ...
(Date:11/27/2015)... ... 2015 , ... The men and women on this list ... the country. They have overseen financial turnarounds, shown commitment to their community through ... as a whole through their advocacy and professional efforts. , Becker's Hospital Review ...
(Date:11/27/2015)... ... November 27, 2015 , ... Indosoft Inc., developer and ... of Asterisk 11 LTS (Long Term Support) into its Q-Suite 5.10 product line. ... 5.10 up-to-date with a version of Asterisk that will receive not only security ...
(Date:11/26/2015)... ... November 26, 2015 , ... CognisantMD and Cambridge ... imaging in the Waterloo region. Using the Ocean Platform, family physicians can now ... their electronic medical record (EMR) without the need for redundant patient entry or ...
(Date:11/26/2015)... ... ... Jobs in hospital medical laboratories and in the imaging field lead the ... Aureus Medical Group . These fields, as well as travel nursing, ranked ... jobs through the company’s website, , The leading healthcare staffing agency ...
Breaking Medicine News(10 mins):
(Date:11/27/2015)... , Pays-Bas, November 27, 2015 ... l,immunothérapie au traitement photodynamique au Bremachlorin contre le ... nouvelle approche consistant à combiner l,immunothérapie au traitement ...    --> Une nouvelle approche ... Bremachlorin contre le cancer avancé.    ...
(Date:11/27/2015)... 2015 --> ... online. The potential to save costs, improve treatment quality ... from fully exploited as yet. Here, particular emphasis is ... via mobile tablet or directly at the patients, bedside. ... ) -->      (Photo: ...
(Date:11/27/2015)... November 27, 2015 Ein ... fortgeschrittenem Krebs.   --> Ein neuer ... Krebs.   --> Ein neuer ... Krebs.   Clinical Cancer Research ... Clinical Cancer Research vom 6. November 2015 ...
Breaking Medicine Technology: