Navigation Links
Link between Old Cells and Ageing probed

How much do we know about the connection between age factor and ageing cells? Now, Brown university biologists have found new proof that might establish this connection between old cells and old bodies. //

During a study of baboons, it was discovered that as the baboons aged, their skin showed an increased presence of old cells. It is well known that, as we age, the cells capability to divide, dwindles. This state is termed as replicative senescence. This novel research is the first of its kind that places a finger on the presence of such replicatively senescent cells, published in an advanced online edition of science.

According to John Sedivy, a professor of Medical Science at Brown University and a senior scientist in this project, whether old cells contribute to body aging is a highly controversial topic, prompting the skeptics to question this finding. Although, the initial evidence clearly rests in the recent finding, more needs to be known about how cells multiply anywhere from 60 to90 times prior to the onset of senescence, known to protect the body against disease. Old cells still do their job though not with as much vigor as the young cells and hence the reason for all those wrinkles, slackened healing, cancer and an infirm immune system. There is proof that these senescent cells are not benign, but not enough evidence that their numbers are present in large numbers in aged animals.

This marked the beginning of a study by Brown’s team which involved Baboons from the research preserve aged between 5 and 30 comparable to human age from 15 to 90. Skin samples were extracted from the monkey’s forearms. They were further tested by scientists in the sedivy lab for the presence of six bio markers, which mean the onset of cellular aging. The most important indicator for replicative senescence is telomere dysfunction that stops the division of cells. Infact, scientists did the hair splitting task of counting the cells with bio markers. T heir finding revealed that the number of senescent cells increased with advancing age, with cells present in 5 yr olds being as less as 4% compared to a high of 20% in 30 yr olds. Of course this is just the tip of the iceberg; further studies are required to probe deep into the subject.

Utz Herbig ,Brown post-doctoral research fellow is the lead author of the article. Mark Ferreira, Brown undergraduate, Laura Condel and Dee Carey from the Southwest Foundation for Biomedical Research have made noteworthy contributions. This work has been funded by the National Institute on Ageing.


'"/>




Related medicine news :

1. CDC reveals relationship between prepregnant weight and heart defects in infants
2. Link between Constipation and Parkinsons Disease
3. Is there a link between bones and memory?
4. Comparison between warfarin and aspirin
5. No link between blood groups and prostate cancer
6. Link between chlorine byproducts and pregnancy risks
7. No link between bad weather and rheumatism
8. No connection between breast cancer and pill
9. No connection between epidurals and backache
10. Link between birth weight and Insulin Resistance
11. Link between athleticism and neurological disease
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/25/2016)... ... 2016 , ... Austin residents seeking Mohs surgery services, can now turn to ... Dr. Russell Peckham for medical and surgical dermatology. , Dr. Dorsey brings specialization to ... fellowship in Mohs Micrographic Surgery completed by Dr. Dorsey was under the direction of ...
(Date:6/25/2016)... ... June 25, 2016 , ... ... recover from injury. Recently, he has implemented orthobiologic procedures as a method for ... is one of the first doctors to perform the treatment. Orthobiologics are substances ...
(Date:6/24/2016)... ... ... June 19, 2016 is World Sickle Cell Observance Day. In an effort to ... treatments, Serenity Recovery Center of Marne, Michigan, has issued a pain management ... (SCD) is a disorder of the red blood cells, which can cause episodes of ...
(Date:6/24/2016)... ... June 24, 2016 , ... Comfort Keepers® of San ... Society and the Road To Recovery® program to drive cancer patients to and from ... adults to ensure the highest quality of life and ongoing independence. Getting to ...
(Date:6/24/2016)... Nevada (PRWEB) , ... June 24, 2016 , ... ... Vegas client, The Grove Investment Group (TGIG), has initiated cultivation and processing operations ... in Las Vegas and Pahrump, Nevada. , Puradigm is the manufacturer of a ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... , June 24, 2016  Consumers have taken ... regulators/payers have placed more emphasis on patient outcomes. ... support programs in the pharmaceutical industry have evolved ... Consequently, pharmaceutical companies are focusing on becoming more ... providing products and services that improve health. ...
(Date:6/24/2016)... FRANCISCO, Calif. , June 24, 2016 /PRNewswire/ ... ), a biopharmaceutical company developing novel therapeutics for ... unmet needs, today announced the closing of its ... of common stock, at the public offering price ... in the offering were offered by GBT. GBT ...
(Date:6/24/2016)... , June 24, 2016 ... has announced the addition of the " Global ... This report ... provides an updated review, including its applications in various ... total market, which includes three main industries: pharmaceutical and ...
Breaking Medicine Technology: