Navigation Links
Link Between Neuroticism and Depression May be Genetic

Genetic factors may be at play when it comes to the link between the personality trait of neuroticism and vulnerability for depression// , according to a new study by Virginia Commonwealth University researchers.

In the October issue of the journal Archives of General Psychiatry, researchers reported the results from both longitudinal and genetic analyses that showed that neuroticism is a strong predictor for major depression. Using twin modeling, the researchers determined that a substantial proportion of the genetic vulnerability to depression is shared with neuroticism.

“The personality trait of neuroticism - perhaps better understood as “negative emotionality” is a strong risk factor of major depression. Our study shows that this occurs largely because levels of neuroticism are an index of the genetic liability to depression,” said Kenneth S. Kendler, M.D., a professor of psychiatry and human genetics in VCU’s School of Medicine and lead author on the study.

VCU researchers, together with researchers from the Karolinska Institute in Sweden evaluated lifetime major depression of approximately 21,000 same-sex twin pairs born between 1926 and 1958 from the Swedish National Twin Registry. In 1972 and 1973, participants completed a questionnaire containing 18 items selected from a personality test called the Eysenck Personality Inventory that assessed the personality traits of neuroticism and extroversion.

More than 25 years later, participants were interviewed in person to determine if they developed depression during their lifetime. The study sought to clarify the magnitude and nature of the association between neuroticism, extroversion and risk for major depression.

Kendler and his team found a weak relationship between extroversion and major depression. They concluded that this major dimension of personality has little to do with risk for depression.

Previous studies in literature have report ed that neuroticism or neuroticism-like traits have consistently predicted future depressive episodes.

These results suggest that efforts to identify specific genes that have an impact on risk for depression might be considered also using neuroticism as a target trait.


Related medicine news :

1. Link Between Infection And Heart Disease
2. Prescription Drug Use Varies Widely Between States
3. Wait Between Pregnancies
4. Link Between Migraines and Behavioral Disorders
5. Link Between Obesity and Behavior in Kids
6. Link Between Mothers Depression and Violence in Children
7. Link Between Alcohol and Decrease in Brain Size
8. Link Between Musculoskeletal Pain and Vitamin D Deficiency
9. Link Between Hyperglycemia & Hospital Mortality
10. Link Between Alcohol Consumption And Cardiovascular Disease
11. Understanding The Link Between Hormone Replacement and Respiratory Disease
Post Your Comments:

(Date:11/30/2015)... ... November 30, 2015 , ... ... provider of enterprise Time and Attendance/Workforce Management cloud-based solutions, announced today that ... Program with competencies in the Application Development, demonstrating a “best-in-class” ability and ...
(Date:11/30/2015)... ... November 30, 2015 , ... ... partnership at the Radiological Society of North America (RSNA) 2015 conference. , ... of cutting-edge dictation and speech-enabled documentation software, announced their partnership today at ...
(Date:11/30/2015)... ... November 30, 2015 , ... ... dealer. Joining more than 30 HealthPostures’ dealers located throughout the United States, is ... the number of corporate, industrial, manufacturing and government workers and organizational leaders that ...
(Date:11/30/2015)... ... November 30, 2015 , ... World Patent Marketing ... Swappables, a household invention that provides an economical and easy way of gaining ... is growing at 2.6%," says Scott Cooper, CEO and Creative Director of World ...
(Date:11/30/2015)... ... November 30, 2015 , ... CTI Group (Holdings) Inc. (OTC:CTIG), ... through communication analytics, announced today that their Proteus® VoIP QMS solution now supports ... , Proteus® VoIP QMS (Quality Management System) does this by collecting ...
Breaking Medicine News(10 mins):
(Date:11/30/2015)... Wash. , Nov. 30, 2015  Precision ... Post-Processing services, is pleased to announce a dramatic ... medical imaging services. Building on its ISO-9001:2008 certification ... and implemented comprehensive Core Lab protocols and procedures. ... variety of research activities.  Their Core Lab services ...
(Date:11/30/2015)... , November 30, 2015 PFE ... at up to 10 G protein-coupled receptor (GPCR) targets ... to research and develop potential new medicines directed at ... multiple therapeutic areas. --> Heptares Therapeutics ("Heptares"), ... and wholly-owned subsidiary of Sosei Group Corporation ("Sosei"; TSE ...
(Date:11/30/2015)... 30, 2015 Mexico Healthcare and Life Sciences ... Report 2015 . --> Pharmaboardroom releases its new 98-page ... Latin America , a country of over 122 million ... of over 122 million people. --> It offers companies, ... life sciences insights into the second largest pharma and healthcare market ...
Breaking Medicine Technology: