Navigation Links
Link Between Food Cue-related Brain Activity Found

A unique pattern of gene expression observed in rats may be linked to a conditioned desire for food and excessive food intake, an article published today// in BMC Biology suggests.

It's well known that food-associated cues, such as advertising, can influence food intake. But the underlying neurobiology is far from clear. Craig A. Schiltz and colleagues from the University of Wisconsin Madison School of Medicine and Public Health, USA, created an experimental set up that allowed them to study patterns of gene expression linked to this motivational state - rats conditioned to expect a chocolate-flavoured treat in a particular environment, were subsequently denied their reward.

The research, conducted in the laboratory of Ann E. Kelly showed that expression of a handful of immediate early genes was increased in cortical, striatal, thalamic and hypothalamic brain regions. Food-related cues triggered dramatic changes in the functional connectivity of circuits involved in adaptive behaviour. For example, increased connectivity was seen between the cortex and two other regions - the amygdala and the striatum. Within the latter, there was a shift in activity from the outer shell to the inner core of the nucleus accumbens and an increased expression of the opioid-encoding proenkephalin gene.

Taken together, these results suggest that food-associated cues have a powerful influence on neuronal activity and gene expression in brain areas mediating complicated functions such as cognition and emotion, and more basic abilities such as arousal and energy balance. The pattern of activation differs from that elicited by neutral cues, and may well contribute to a conditioned motivational state that can lead to excessive food intake.

Source-Eurekalert/B
'"/>




Page: 1

Related medicine news :

1. Link Between Infection And Heart Disease
2. Prescription Drug Use Varies Widely Between States
3. Wait Between Pregnancies
4. Link Between Migraines and Behavioral Disorders
5. Link Between Obesity and Behavior in Kids
6. Link Between Mothers Depression and Violence in Children
7. Link Between Alcohol and Decrease in Brain Size
8. Link Between Musculoskeletal Pain and Vitamin D Deficiency
9. Link Between Hyperglycemia & Hospital Mortality
10. Link Between Alcohol Consumption And Cardiovascular Disease
11. Understanding The Link Between Hormone Replacement and Respiratory Disease
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/22/2017)... ... March 22, 2017 , ... The Jim Shortridge Agency, an ... business owners, is joining the Teen Recovery Solutions organization in a charity event ... growing number of Oklahoma teens and adolescents face problems from drugs, alcohol, abuse, ...
(Date:3/22/2017)... Massapequa, NY (PRWEB) , ... March 22, 2017 ... ... offering insurance, financial planning assistance, and related services to families and business owners ... drive in cooperation with the Leukemia & Lymphoma Society. , Every 3 minutes, ...
(Date:3/22/2017)... ... March 22, 2017 , ... ... and financial planning assistance to communities throughout central Ohio, is initiating a charity ... Estimates from the Department of Defense and the Veteran's Brain Injury Center conclude ...
(Date:3/22/2017)... ... March 22, 2017 , ... The Senior Citizens League ... prevent a default on the federal debt — including the debt held by the ... concern, ” said TSCL in a letter to House and Senate budget leaders. ...
(Date:3/22/2017)... CHICAGO, ILLINOIS (PRWEB) , ... March 22, 2017 ... ... that virtually guarantee patient payments for providers while creating a positive patient experience. ... estimation engine that further educates and empowers patients by helping them understand their ...
Breaking Medicine News(10 mins):
(Date:3/22/2017)... LINCOLN, Mass. , March 22, 2017 /PRNewswire/ ... applying mechanistic modeling to drug research and development, ... QSP Day 2017.  QSP Day 2017 is a ... with the quantitative systems pharmacology (QSP) community. The ... mathematical modeling is de-risking and accelerating drug research ...
(Date:3/22/2017)... Massachusetts , March 22, 2017 ... solutions, announced today that Newton-Wellesley Hospital, a nationally recognized medical ... significant improvement in patient outcomes following continued implementation of its ... overall reduction of 59% in median nurse response time to ... ...
(Date:3/22/2017)... 2017 Hologic, Inc. (Nasdaq: HOLX ... of Cynosure, Inc., a leader in medical aesthetics systems ... "We are pleased to complete our acquisition of ... Davin and the entire Cynosure team to achieve ... aesthetics market," said Steve MacMillan , Hologic,s Chairman, ...
Breaking Medicine Technology: