Navigation Links
Light-activated Compound May Be of Help for Epileptics in Future

scent tag to the steroid had disabled it.

"Normally, the steroid keeps the cell quiet in the face of stimuli that would otherwise cause it to fire," Mennerick says. "That's why drugs like barbiturates and Valium, which act on the same receptor as the steroid, are sedatives—they quiet the nerve system down."

When dosed with NBD-steroid, nerve cells still responded to stimuli as readily as they had prior to exposure. Just to see where the modified steroid was going, though, researchers exposed the cells to light.

"All of a sudden, the response to the steroid was back, and the nerve cells were more reluctant to react to stimuli," Mennerick says. "And we knew we had found something very interesting."

To confirm what was happening, scientists dosed two of a nerve cell's many different branches with NBD-steroid. When they shone a light on one of the branches, its readiness to respond decreased, while the readiness of the branch not exposed to light remained the same.

Department of Anesthesiology colleagues tested the compound's effects on tadpoles.

"Tadpoles rapidly take up drugs through their skin, so they're frequently used to test potential anesthetics," Mennerick notes. "And of course, given that it's a photoactive drug, they make a nice test subject because they're mostly translucent."

Tadpoles swimming in a solution of NBD-steroid went to sleep at the bottom of their beaker when exposed to light.

Mennerick and his colleagues are currently seeking to identify or create an animal model of epilepsy that lets them test the NBD-steroid's potential as a therapeutic. They are also looking for a new fluorescent tag that responds to longer wavelengths of light. Unlike many photoactive compounds, the NBD-steroid responds not to ultraviolet light but to light from the blue region of the electromagnetic spectrum. This helps because the longer wavelengths of blue light penetrate far
'"/>




Page: 1 2 3

Related medicine news :

1. Compound of Broccoli combats breast cancer
2. New Compound Could Strengthen The Effect Of Chemotherapy
3. Breathing Cancer Causing Compounds During Pregnancy Found To Affect Offspring
4. Compound from cottonseed for neck and head cancers
5. Compounds Found In The Vegetable Broccoli Could Have Anti-Cancer Properties
6. Adding Sorghum Compounds To Dietary Supplements May Help Lower Cholesterol
7. Compound In Grapes And Red Wine To Counter Alzheimers Disease
8. Sugars Could Contain Key Cancer Inhibiting Compounds
9. Compound From Cyanobacterium Can Fight Alzheimer’
10. Five New Anti-Inflammatory Compounds Produced By Indian Scientists
11. Compounds in Licorice Can Fight Tooth Decay
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Light activated Compound May Help for Epileptics Future

(Date:2/27/2015)... Calif. (PRWEB) February 27, 2015 Hispanics ... liver-disease death, between four and 12 years earlier than ... from UC Davis Health System. , While previous research ... than other populations, the new study -- published online ... is believed to be the first to pinpoint racial ...
(Date:2/27/2015)... Santa Clara, CA (PRWEB) February 27, 2015 ... Integrated Passive Devices (IPD), has introduced miniature, wire bondable, ... Brightness and Power LED markets. The ESD88NP ... high transient currents away from sensitive LED and IC ... compared to Multilayer Varistors (MLV). All devices meet ...
(Date:2/27/2015)... 27, 2015 Just a little over ... those suffering from Sjögren’s Syndrome after a new autoantibody ... at the University of Buffalo and Immco Diagnostics, Inc. ... was to develop a new diagnostic test ... of new autoantibodies. Researchers aimed to develop a test ...
(Date:2/27/2015)... Today, February 27th, is "Shine A Light On Slavery Day" ... Organics and Living Fuel, Inc. , have linked ... promote prevention, rescue and restoration for people held in slavery. ... slavery is the 2nd largest global organized crime, generating 150.2 ... the world. Slavery includes bonded labor, forced labor, and human ...
(Date:2/27/2015)... Sunnyvale, CA (PRWEB) February 27, 2015 ... showcase ClinCapture, its validated Electronic Data Capture (EDC) at ... Francisco, California on March 2nd and March 3rd at ... a self-service platform and DIY CRF and edit-check builder ... Checks in a matter of days, without any programming ...
Breaking Medicine News(10 mins):Health News:UC Davis Study Finds Hispanics Develop Alcoholic Liver Disease at Younger Ages than Caucasians or African Americans 2Health News:OnChip Introduces New Series of Space Saving Bare-die Zener Diodes for Transient Voltage Suppression 2Health News:OnChip Introduces New Series of Space Saving Bare-die Zener Diodes for Transient Voltage Suppression 3Health News:Breakthrough Blood Test for Early Detection of Sjögren’s Syndrome Now Available 2Health News:KAJ Brothers Join the Campaign to 'End It - Shine A Light On Slavery' 2Health News:Clinovo to Demo Its Self-Service, Cloud-Based EDC Solution at CALBIO2015 on March 2nd and 3rd, 2015 2
... developments bring social and economic benefits to the ... to predict and manage. With rapid advances in ... are increasingly exposed to EMFs at an earlier ... and exposure to extremely low frequency (ELF) magnetic ...
... United Kingdom Trade and Investment’s (UKTI) is looking for ... Confederation of Indian Industry, CII had meetings with UKTI ... Health care providers. , ,David Hawkins of UKTI ... as Apollo Hospitals, KG Hospital and Trivitron Medical systems ...
... and health is well recognized, however, it is frequently ... dietary component and a specific health endpoint. This is ... most of them reach humans through the food chain. ... the occurrence of various chemical contaminants of notable concern ...
... Polytechnique Federale de Lausanne) and the CHUV (Lausanne University ... follicle belong to the true multipotent stem cell category ... for hair growth and follicle replacement. , ,The ... online publication of the October 3 issue of Proceedings ...
... disease is an irreversible neurodegenerative disorder with no known ... was known at that time, we have come a ... disease is characterized by symptoms of memory loss, confusion, ... skills. , ,Mild cognitive impairment (MCI) is a ...
... World Health Organization (WHO), shows that 36 million deaths occurs ... stroke, cancer and diabetes and serious measures has to be ... The main factors which are responsible for the cause of ... eating more food rich in fats and sugars, doing less ...
Cached Medicine News:Health News:Hazards of Electromagnetic Fields for children 2Health News:Athletes Are More Prone To Environmental Pollutants Due To Choice Of Diet 2Health News:PET Scanning can help in early detection of Alzheimer’s diseas 2
(Date:2/27/2015)... Report Details   ... R&D progress, and predicted revenues ,Where is the market ... commercial prospects for this market and related technologies? Visiongain,s ... trends to 2025, discussing data, opportunities and prospects. ... regenerative medicine : cell-based therapies that aim to restore ...
(Date:2/27/2015)... ON , Feb. 27, 2015 /CNW/ - Covalon Technologies ... medical technologies company, today announced financial results for its ... For the three months ended December 31, 2014, revenue ... the quarter was $229,820 or $0.02 per share.  ... , said "I am very pleased with the significant ...
(Date:2/27/2015)... February 27, 2015 ... Überwachungssystem für kongestive Herzinsuffizienz (CHF) in seiner ...     Die ... neuartiges Herzüberwachungssystem für Patienten mit kongestiver Herzinsuffizienz ... sie ein Finanzierungsvorhaben über 5 Mio. USD ...
Breaking Medicine Technology:Translational Regenerative Medicine: Market Prospects 2015-2025 2Translational Regenerative Medicine: Market Prospects 2015-2025 3Translational Regenerative Medicine: Market Prospects 2015-2025 4Translational Regenerative Medicine: Market Prospects 2015-2025 5Translational Regenerative Medicine: Market Prospects 2015-2025 6Translational Regenerative Medicine: Market Prospects 2015-2025 7Translational Regenerative Medicine: Market Prospects 2015-2025 8Covalon Announces First Quarter Financial Results 2Covalon Announces First Quarter Financial Results 3Vectorious Medical Technologies schließt Finanzierungsvorhaben über 5 Mio. USD ab 2
... 26, 2011 Endo Pharmaceuticals Holdings Inc. (NASDAQ: ... aggregate principal amount of senior unsecured notes. The notes will ... guaranteed by certain of the Company,s subsidiaries.   ... together with cash on hand and borrowings under its new ...
... May 26, 2011 Hospital and health-system pharmacies ... shortages and promote patient safety with the support ... Technicians (CPhTs). Manufacturing issues, including shortages ... limited manufacturing capacity, and pharmaceutical industry consolidation, have ...
Cached Medicine Technology:Endo Pharmaceuticals Holdings Inc. Announces Proposed Private Offering of Senior Notes 2Pharmacy Technicians Assist Pharmacy Teams in Development of Drug Shortage Protocols 2
... optical performance, the ALM X'Ten is a ... types of applications. , ,Its unique cross-shaped ... the highest standards needed for your surgical ... within the surgical field., ,A 31" column ...
The very bright medical maginifier lamp for examination and labratory....
... Closure Deviceprotects surgeons, nurses, and OR ... threat of disease from deadly bloodborne ... same time enabling Gold Standard wound ... The SuturTek 360Fascia Closure Devicealso protects ...
The Next Generation in Operating Room Equipment and Management Solutions is here Today. NuBoom is a self-contained, pedestal-mounted boom that houses medical, audio and visual equipment....
Medicine Products: