( In a new study conducted by Colorado St...)Life Functions Governed by Circadian Rhythms-new Research,Health

In a new study conducted by Colorado State University shows that circadian rhythms dominate all life function. The functions of all the genes in the mammals are according to this daily rhythm. It disproves the prior theory that only 10 to 15% of genes were affected by the natures clock. It was earlier believed that some special function of the genes was the basic property of the organism. But these conclusion are refuted by the new study.The new study emphasises oscillation as a basic property of all genes in the organism. Daily life functions and metabolism are dominated by the circadian rhythm, thus regulating behaviour pattern of living.

Knowing about oscillation properties of genes involved in metabolism is essential for understanding how genes interact with and regulate health and disease. Colorado State University researcher Andrey Ptitsyn's new analysis of data collected through several studies establishes a baseline oscillation in 98 to 99 percent of all genes through advanced computer algorithms. Most of these genes have never been previously reported as changing their expression level in a daily cycle. Some of these genes, considered "housekeeping," have been used as a stable reference platform in gene expression studies.

"Anyone who diets, for example, knows you shouldn't eat late, and now we are getting closer to understanding why exactly," said Ptitsyn, a researcher in the Bioinformatics Center at the College of Veterinary Medicine and Biomedical Sciences. The center is located in the Department of Microbiology, Immunology and Pathology. "We discovered that all genes have a significant change in pattern of activity -- or expression -- throughout the day. Every pathway of gene expression is affected by circadian rhythms, and the timing of the rhythms from each group of genes that are synchronized is important."

Ptitsyn also discovered alternative short and long copies of some genes oscillating in the opposite phase.
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