Navigation Links
Leptin and inflammatory cytokines in women with pre-eclampsia

Recent research shows that in women with pre-eclampsia, the level of maternal serum leptin is increased and correlates positively with the level of inflammatory cytokines, TNF-á//.

The research was conducted at University Hospital of Puerto Real, Cadiz, Spain to compare maternal serum leptin concentration in women with pre-eclampsia and women with normal pregnancy, and to evaluate the relationships between leptin and several inflammatory cytokines.

The study appears in the December issue of British Journal of Obstetrics and Gynaecology.

Leptin is a hormone that regulates metabolic efficiency, energy expenditure, and food intake. It is mainly produced in adipose cells, but in humans, m-RNA encoding leptin is also present in the placenta.

Pre-eclampsia is associated with an increase in maternal plasma leptin concentration, and it has been demonstrated that placental production of leptin is augmented in women with severe pre-eclampsia

Twenty-seven women with pre-eclampsia and 25 normotensive pregnant women were enrolled for the study. Maternal serum levels of TNF-á, TGF-a1, interleukin 6, and leptin were measured using a commercially available immunoassay.

The authors conclude that the level of maternal serum leptin is increased and correlates positively with the level of TNF-á in women with pre-eclampsia. In women with a normal pregnancy leptin levels not only correlate with TNF-á, but also with IL-6 and body mass inde.
'"/>




Page: 1

Related medicine news :

1. Leptin connected to obesity blood clots
2. Leptin linked to Blood Clots
3. Weight gain following smoking cessation not linked to Leptin
4. Leptin is "new breast cancer indicator"
5. Hormone Leptin Found To Be Effective In Treating Women With Infertility Problems
6. Scientists crack mechanism of Leptin-Obesity Hormone
7. Obesity Hormone - Leptin may treat Metabolic Disorder
8. Leptin Hormone Plays Key Role In Losing Weight
9. Leptin Injections Maintain Loss In Body Weight
10. Leptin, The Next Generation Antidepressant?
11. Leptin Plays A Vital Role among Female Patients Suffering From Asthma
Post Your Comments:
Breaking Medicine Technology:Pro-Dex, Inc. Announces Results of Annual Shareholder Meeting, an Update Regarding Major Customer's Product Development Plans, and Receipt of $1.5 Million and $3.0 Million Purchase Orders 2Pro-Dex, Inc. Announces Results of Annual Shareholder Meeting, an Update Regarding Major Customer's Product Development Plans, and Receipt of $1.5 Million and $3.0 Million Purchase Orders 3Pro-Dex, Inc. Announces Results of Annual Shareholder Meeting, an Update Regarding Major Customer's Product Development Plans, and Receipt of $1.5 Million and $3.0 Million Purchase Orders 4Chinese-American Women & Korean-American Women at Highest Risk for Developing Diabetes During Pregnancy 2Chinese-American Women & Korean-American Women at Highest Risk for Developing Diabetes During Pregnancy 3Chinese-American Women & Korean-American Women at Highest Risk for Developing Diabetes During Pregnancy 4Genomic Health Announces Publication of Study of Oncotype DX(R) in Node-Positive Breast Cancer That Identifies Patients Who Do Not Appear to Benefit From Chemotherapy 2Genomic Health Announces Publication of Study of Oncotype DX(R) in Node-Positive Breast Cancer That Identifies Patients Who Do Not Appear to Benefit From Chemotherapy 3Genomic Health Announces Publication of Study of Oncotype DX(R) in Node-Positive Breast Cancer That Identifies Patients Who Do Not Appear to Benefit From Chemotherapy 4Genomic Health Announces Publication of Study of Oncotype DX(R) in Node-Positive Breast Cancer That Identifies Patients Who Do Not Appear to Benefit From Chemotherapy 5VIA Pharmaceuticals Featured at Cambridge Healthtech Institute Discovery on Target 2009 Conference 60314 1VIA Pharmaceuticals Featured at Cambridge Healthtech Institute Discovery on Target 2009 Conference 60314 2VIA Pharmaceuticals Featured at Cambridge Healthtech Institute Discovery on Target 2009 Conference 60314 3VIA Pharmaceuticals Featured at Cambridge Healthtech Institute Discovery on Target 2009 Conference 60314 4VIA Pharmaceuticals Featured at Cambridge Healthtech Institute Discovery on Target 2009 Conference 60314 5CHEENY KUM 3A The Mobile Online Way to Monitor Diabetes 60310 1CHEENY KUM 3A The Mobile Online Way to Monitor Diabetes 60310 2Novavax Announces Poster Presentation at the 47th Annual Meeting of the IDSA 14642 1Novavax Announces Poster Presentation at the 47th Annual Meeting of the IDSA 14642 2