Navigation Links
Leeches Provide Clues Regarding The Prevention Of Heart Disease

Cardiovascular diseases have now become common place owing to the wide scale industrialization and subsequent// change in life style. Time and over again, scientists have been working on ways to prevent or treat heart ailments without surgical intervention. The results of a recent research have recently confirmed that leeches could be used in the treatment of cardiovascular diseases.

The leeches have added to the biomedical interest by showing that it contains an extensive list of new potential molecules that may become useful tools. There has been an increasing tendency to turn towards blood-feeding invertebrates as a source for drugs and lead compounds to treat cardiovascular disease because these animals have evolved highly efficient mechanisms to feed on their hosts by blocking blood coagulation.

Most heart attacks and strokes are associated with a blocked artery and in a majority of the cases; blood clots may cause the blockage of blood vessels supplying the heart, leading to heart disease. Furthermore, people with cardiovascular disease typically have an increased tendency to form blood clots, and a decreased ability to dissolve clots before they can do any damage. Therefore, compounds interrupting the blood coagulation cascade may inhibit thrombus development as well.

The researchers have identified and analyzed peptides and small proteins in the saliva of the medical leech Hirudo medicinalis for their ability to bind to molecules called serine proteases. These molecules have the ability to prevent coagulation or clotting of blood.

Of the nearly 2,000 molecules the researches screened, more than 75 of them interacted specifically with the fixed target and 16 of these binding molecules were isolated and subsequently characterized as new inhibitors that had potential to be used as drugs in treating cardiovascular disease.

Although these newly discovered molecules are a long way from being used to treat cardiovasc ular disease, they do represent several important leads in the search for more effective anticoagulant and fibrinolytic drugs. The research tem has also expressed interest towards screening of different types of leeches and other blood sucking animals for their anti-coagulant potential.

Medindia on chest pain:

Some causes of chest pain require prompt medical attention, such as angina, heart attack, or tearing of the aorta. Other causes of chest pain can be evaluated electively, such as spasm of the esophagus, gallbladder attack, or inflammation of the chest wall.
'"/>




Related medicine news :

1. Leeches help in tissue transfer
2. Drug Spironolactone Provides Renal And Cardioprotection In Diabetic Patients
3. Neurobiology Provides Answers To Block Memory-Related Drug Cravings
4. Reliance Infocomm Tied With Apollo To Provide Telemedicine Services
5. Apollo Hospitals Short-listed to Provide Diagnostics in the UK
6. Reindeer Provide Valuable Insights Into Sleep Disorders
7. London Hospital Provides Specialized Care For Pregnant Women
8. CNIC To Provide Funds To Mount Sinai School
9. Clean Blades To Be Provided To Self-Harmers
10. Breastfeeding Provides Added Protection To Babies
11. Court Orders Private Hospitals To Provide Free Treatment For The Poor
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... October 13, 2017 , ... ... Randall, PharmD ‘17, and Jennifer Huggins, PharmD ’17, along with clinical associate ... primary prevention of cardiovascular diseases during the 15th Annual Women’s Health Conference. ...
(Date:10/13/2017)... LUIS OBISPO, Calif. (PRWEB) , ... October 13, 2017 , ... ... Alzheimer’s or dementia. However, many long-term care insurance companies have a waiver for care ... is the 90-day elimination period, when the family pays for care, is often waived, ...
(Date:10/13/2017)... ... , ... Global Healthcare Management’s 4th Annual Kids Fun Run brought out many ... event, sponsored by Global Healthcare Management’s CEO, Jon Letko, is aimed at getting kids ... of all ages; it is a non-competitive, non-timed event, which is all about having ...
(Date:10/13/2017)... VA (PRWEB) , ... October 13, 2017 , ... ... of DevOps and Agile Software Development, has been awarded a contract by the ... Blanket Purchase Agreement (BPA) aims to accelerate the enterprise use of Agile methodologies ...
(Date:10/12/2017)... ... October 12, 2017 , ... First Healthcare Compliance (FHC), an ... showcase a range of technology and learning solutions at the 68th Annual American ... to be held October 14–18, 2017 at the Mandalay Bay Resort in Las ...
Breaking Medicine News(10 mins):
(Date:10/2/2017)... COPENHAGEN, Denmark , Oct. 2, 2017 The ... tool in the struggle to reverse the tide of prescription ... plan for regulating their medicine intake and stepping down their ... is set to launch in December 2017; the first 100,000 ... access. Learn more at http://www.rebound-solution.com/ ...
(Date:9/25/2017)... Sept. 25, 2017   Montrium , an ... solutions, today—from the IQPC Trial Master Files & ... NL)—announced that EastHORN Clinical Services has selected ... and TMF management. EastHORN, a leading European contract ... to increase transparency to enable greater collaboration with ...
(Date:9/19/2017)... , Sept. 19, 2017 HistoSonics, Inc., a venture-backed medical device company developing a ... targeted tissues, announced three leadership team developments today:   ... ... ... Veteran medical device executive Josh Stopek , ...
Breaking Medicine Technology: