Navigation Links
Latest Tumor Classification More Informative

Clinicians say information about the genetic make-up of tumors help them decide on the most effective course of treatment for patients with cancer. To be most helpful these molecular data must be incorporated into a tumor classification // that includes morphological and clinical information.

Specialists say, "The latest classification is simple (reducing the complexity of information received from the molecular analysis of tumors), comprehensive (providing a place for every tumor of man), and consistent with recent attempts to characterize tumors by cytogenetic and molecular features."

Traditionally, tumors have been classified by their morphologic appearances, but unfortunately, tumors with similar histologic features often follow different clinical courses or respond differently to chemotherapy. The alternative, a classification based solely on the molecular characteristics of tumors, would sacrifice the clinical/pathological experiences that inform virtually every clinical decision related to the diagnosis and treatment of patients with cancer. Both the type of cells from which a tumor is derived and the molecular characteristics of those cells determine how a tumor will behave – information of great importance to clinicians.

At the highest level of the classification, tumors are grouped according to the component cells' developmental history – their 'histogenesis'. For example leukemia would be classified as a mesenchyme-derived tumor. Patterns identified from the gene expression and proteomic data from tumor samples can then be integrated as new groups within this classification.

As each tumor is derived from a cell with an individual lineage, it will have a unique position within the classification. The commonly used tumor classifications list tumors by the body site of origin. However, every organ contains connective tissue, vessels, and lymphoid tissue. When you start to list the tumors that can occur in an organ, y ou find that every organ can develop many of the same tumors. Classifications that are organized by anatomic site become massively redundant, and this becomes a major problem when dealing with many thousands of tumor terms that link to other biologic datasets.

The most important value of this (new) classification is the disengagement of tumor type and tumor place of origin…This permits tumors with similar molecular profiles to be classified according to biological attributes rather than anatomical location , say researchers.
'"/>




Related medicine news :

1. Latest device for identifying Melanomas
2. Latest discovery on Autism
3. Latest device for cardiac revival under test
4. Latest technique for asthma treatment
5. Latest drug shows promise in multiple myeloma
6. Latest Findings On The Deadly Disease - SARS
7. The Latest Preventative Treatment Option for Prostate Cancer
8. Latest Research Shows That Multivitamins Might Not Prevent Infections In All Elderly
9. A Latest Study Links Fish To Stroke
10. Enhanced Gene Therapy Outcomes Following Latest Revolution And Refinement
11. Lovers Latest Hang Outs – Railway Platform
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/23/2017)... ... June 23, 2017 , ... Ulster University, Magee Campus ... from 9 am to 3 pm to present to graduate students exciting new and ... an original curriculum project led by The Health Improvement Service of the Western Health ...
(Date:6/23/2017)... ... June 23, 2017 , ... Radabaugh & Associates, ... families and business owners in North Central West Virginia, is embarking on a ... differently abled residents in the region. , The Stepping Stones organization offers a ...
(Date:6/22/2017)... Indianapolis, IN (PRWEB) , ... June 22, 2017 ... ... employee benefits advisory organization, is pleased to welcome Whipple & Company as its ... on the clear purpose of balancing their clients’ risk while tailoring optimized benefit ...
(Date:6/22/2017)... , ... June 22, 2017 , ... ... awards for environmental excellence. Maryland Recycling Network has awarded the Baltimore VA Medical ... Outstanding Small Government Program Award for its efforts to promote waste reduction and ...
(Date:6/20/2017)... ... June 20, 2017 , ... ... that Claritas Capital, a Nashville-based private equity firm, has invested $3.35 million in ... for some time, and Claritas Capital offers the smart money, speed to market ...
Breaking Medicine News(10 mins):
(Date:6/8/2017)... 8, 2017  Less than a month ago, amateur ... 200,000 companies, including hospital networks, in over 150 countries. ... of the largest online extortion attempts ever recorded. With ... it is imperative that providers understand where the risks ... this — and many other very real cyber threats.  ...
(Date:6/7/2017)... GAITHERSBURG, Md. , June 7, 2017  Novavax, Inc., ... the second of two Phase 2 trials of its RSV ... women of child bearing age have been published in the ... this publication have been shared in prior scientific conferences). The ... trial in April 2014. Novavax is developing the RSV F ...
(Date:6/3/2017)... -- Eli Lilly and Company (NYSE: LLY ... 3 MONARCH 2 study showed that abemaciclib, a ... with fulvestrant, significantly improved progression-free survival (PFS) compared ... hormone-receptor-positive (HR+), human epidermal growth factor receptor 2-negative ... progressed after endocrine therapy (median PFS, 16.4 vs. ...
Breaking Medicine Technology: