Navigation Links
Laser-based System for Non-invasive Diagnosis of Skin Cancers on the Anvil

Duke University chemists have demonstrated a laser-based system that can capture three-dimensional images of the chemical and structural changes taking place beneath the surface of human skin.

They say that their work is the first step towards non-surgical screening for malignant skin cancers.

"The standard way physicians do a diagnosis now is to cut out a mole and look at a slice of it with a microscope," said Warren Warren, the James B. Duke Professor of chemistry, radiology and biomedical engineering, and director of Duke's new Center for Molecular and Biomedical Imaging.

"What we're trying to do is find cancer signals they can get to without having to cut out the mole. This is the first approach that can target molecules like hemoglobin and melanin and get microscopic resolution images the equivalent of what a doctor would see if he or she were able to slice down to that particular point," said the researcher.

The distributions of hemoglobin, a component of red blood cells, and melanin, a skin pigment, serve as early warning signs for skin cancer growth. But because skin scatters light strongly, simple microscopes cannot be used to locate those molecules except right at the surface.

Warren says that the new technology developed by him and his colleagues is capable of coaxing both hemoglobin and melanin inside questionable skin moles to emit light by exciting them with highly controlled laser pulses.

The non-invasive technique uses a delicate interplay between two laser beams, each emitting a different color of light. In order to keep the skin from overheating in the process, the lasers must also be able to pulse on for only femtoseconds, a thousand trillionths of a second, at a time.

Warren says that the glow of the hemoglobin, and melanin-bearing structures can be magnified by a microscope outside the skin and manipulated by computers to create cellular-scale i mages. He feels that the new technique may enable doctors to see as much as a millimeter below the skin's surface.

"What this is leading to is for a doctor to be able to touch a mole with a fiberoptic cable and characterize what is going on inside it. Today, if you visit a dermatologist, he or she will probably see many moles on your body. But the difficulty is trying to figure out which of those, if any, are dangerous," he said.

The researchers are now working with James Grichnik, an assistant professor in the Duke Medical Center's dermatology and cell biology departments, to begin testing the technology in the clinic.

"We have proposals pending for developing a compact laser system that could be sitting in a dermatologist's office here at Duke within three years where we could actually have the first human demonstrations," Warren said.


'"/>




Related medicine news :

1. Early Warning System For Breast Cancer
2. Gene connected to Multi-System disorder discovered
3. Reviving the Immune System
4. Painkilling Patch As Effective As Intravenous Delivery Systems
5. Wrestling found To Be Good for the Immune System
6. Computer System To Predict Deep Vein Thrombosis
7. Gene-Nanoparticle Gene Transfer Is Better Than Viral Vector Transfer System
8. Nutrient Profiling System Launched By Food Officials in UK
9. Block Immune System Chemical For Treating Asthma
10. Smoking Hazardous To The Enzymes System In Lungs
11. HIIP- A Novel Inhaled Insulin Delivery System As An Alternative To Injectable Insulin Therapy
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/13/2016)... Angeles, California (PRWEB) , ... February 13, 2016 , ... ... help landing a date for the big day. A great outfit, flawless hair, and ... ashtray, they might as well resign themselves to a night at home with Rover. ...
(Date:2/13/2016)... Viejo, CA (PRWEB) , ... February 13, 2016 , ... ... ember particle overlays to footage all within Final Cut Pro X. Each user can ... control over 3D rotation, angle of view, blur, focus offset, hue, saturation, value, contrast, ...
(Date:2/13/2016)... ... February 13, 2016 , ... Christie Medical ... in-kind gift of a VeinViewer® Vision vein finder for the nursing ... start an IV and draw blood, combining technology with traditional technique. , “VeinViewer ...
(Date:2/13/2016)... ... , ... DDi , a Makro company, makes it ... expertise in eClinical Solutions. DDi has built its solution competency with a unique ... clients. DDi provides smarter technology for Clinical Development, Regulatory and Enterprise domains by ...
(Date:2/12/2016)... ... February 12, 2016 , ... The law firm of Morrow, Morrow, Ryan & ... purpose of these scholarships is to encourage applicants to pursue a degree in their ... these two parishes. , “We have available jobs in St. Landry and Evangeline ...
Breaking Medicine News(10 mins):
(Date:2/11/2016)... 2016  Kindred Biosciences, Inc. (NASDAQ: KIN ), ... lives of pets, today announced the submission to FDA ... Drug Application (NADA) for Zimeta™ (dipyrone injection, KIND-012).  Positive ... Zimeta for the control of pyrexia (fever) in horses ... --> --> The Chemistry, Manufacturing, and ...
(Date:2/11/2016)... , Feb. 11, 2016   Health 2.0 ... of new health technologies, announced today " 10 Year ... in health tech over the past ten years.   ... nearly a decade, Health 2.0 has served as the ... and connected with thousands of technologies, companies, innovators, and ...
(Date:2/11/2016)... 11, 2016  MiMedx Group, Inc. (NASDAQ: MDXG ... membrane and other birth tissues, human skin and bone, ... market advanced products and therapies, announced today that it ... Healthcare Conference in New York , ... Michael J. Senken , Chief Financial Officer and ...
Breaking Medicine Technology: