Navigation Links
Laser-based System for Non-invasive Diagnosis of Skin Cancers on the Anvil

Duke University chemists have demonstrated a laser-based system that can capture three-dimensional images of the chemical and structural changes taking place beneath the surface of human skin.

They say that their work is the first step towards non-surgical screening for malignant skin cancers.

"The standard way physicians do a diagnosis now is to cut out a mole and look at a slice of it with a microscope," said Warren Warren, the James B. Duke Professor of chemistry, radiology and biomedical engineering, and director of Duke's new Center for Molecular and Biomedical Imaging.

"What we're trying to do is find cancer signals they can get to without having to cut out the mole. This is the first approach that can target molecules like hemoglobin and melanin and get microscopic resolution images the equivalent of what a doctor would see if he or she were able to slice down to that particular point," said the researcher.

The distributions of hemoglobin, a component of red blood cells, and melanin, a skin pigment, serve as early warning signs for skin cancer growth. But because skin scatters light strongly, simple microscopes cannot be used to locate those molecules except right at the surface.

Warren says that the new technology developed by him and his colleagues is capable of coaxing both hemoglobin and melanin inside questionable skin moles to emit light by exciting them with highly controlled laser pulses.

The non-invasive technique uses a delicate interplay between two laser beams, each emitting a different color of light. In order to keep the skin from overheating in the process, the lasers must also be able to pulse on for only femtoseconds, a thousand trillionths of a second, at a time.

Warren says that the glow of the hemoglobin, and melanin-bearing structures can be magnified by a microscope outside the skin and manipulated by computers to create cellular-scale i mages. He feels that the new technique may enable doctors to see as much as a millimeter below the skin's surface.

"What this is leading to is for a doctor to be able to touch a mole with a fiberoptic cable and characterize what is going on inside it. Today, if you visit a dermatologist, he or she will probably see many moles on your body. But the difficulty is trying to figure out which of those, if any, are dangerous," he said.

The researchers are now working with James Grichnik, an assistant professor in the Duke Medical Center's dermatology and cell biology departments, to begin testing the technology in the clinic.

"We have proposals pending for developing a compact laser system that could be sitting in a dermatologist's office here at Duke within three years where we could actually have the first human demonstrations," Warren said.


'"/>




Related medicine news :

1. Early Warning System For Breast Cancer
2. Gene connected to Multi-System disorder discovered
3. Reviving the Immune System
4. Painkilling Patch As Effective As Intravenous Delivery Systems
5. Wrestling found To Be Good for the Immune System
6. Computer System To Predict Deep Vein Thrombosis
7. Gene-Nanoparticle Gene Transfer Is Better Than Viral Vector Transfer System
8. Nutrient Profiling System Launched By Food Officials in UK
9. Block Immune System Chemical For Treating Asthma
10. Smoking Hazardous To The Enzymes System In Lungs
11. HIIP- A Novel Inhaled Insulin Delivery System As An Alternative To Injectable Insulin Therapy
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... Austin residents ... the American College of Mohs Surgery and to Dr. Russell Peckham for medical and ... highly effective treatment for skin cancer. The selective fellowship in Mohs Micrographic Surgery completed ...
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... "With 30 ... their specific project," said Christina Austin - CEO of Pixel Film Studios. , ... and all within Final Cut Pro X . Simply select a ProHand generator ...
(Date:6/25/2016)... ... June 25, 2016 , ... As a lifelong Southern ... Laude and his M.D from the David Geffen School of Medicine at UCLA. He ... Los Angeles to complete his fellowship in hematology/oncology at the UCLA-Olive View-Cedars Sinai program ...
(Date:6/25/2016)... ... ... On Friday, June 10, Van Mitchell, Secretary of the Maryland Department of Health and ... their exemplary accomplishments in worksite health promotion. , The Wellness at Work Awards took ... the BWI Marriott in Linthicum Heights. iHire was one of 42 businesses to receive ...
(Date:6/24/2016)... ... ... A recent article published June 14 on E Online details ... to state that individuals are now more comfortable seeking to undergo not only the ... and cheek reduction. The Los Angeles area medical group, Beverly Hills Physicians (BHP) notes ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... 26, 2016 One of Australia,s ... formation of a new biotechnology company, Noxopharm Limited [ABN 50 608 ... IPO and to list on the ASX. Noxopharm is ... to enter a Phase 1 clinical study later this year. ... one of the biggest problems facing cancer patients - the ability ...
(Date:6/26/2016)... , June 27, 2016 Jazz Pharmaceuticals ... waiting period under the Hart-Scott-Rodino Antitrust Improvements Act of ... acquisition of Celator Pharmaceuticals, Inc. ("Celator"; Nasdaq: ... p.m. (Eastern Daylight Time). As previously announced ... into a definitive merger agreement under which Jazz Pharmaceuticals ...
(Date:6/26/2016)... June 27, 2016  VMS Rehab Systems, Inc. ( ... take whatever measures required to build a strong and ... is currently listed on the OTC Markets-pink current trading ... and CEO, "We are seeing an anomaly in market ... not only by the Company, but shareholders and market ...
Breaking Medicine Technology: