Navigation Links
Laryngeal Cancer Added to Asbestos’ Crime Lis

Asbestos that has long been associated with mesothelioma and lung cancer has now been found to cause laryngeal malignancies as well //.

The Indian Institute of Medicine revealed this finding in its report. In addition IOM also concluded that there was ‘suggestive but not sufficient’ evidence to point out conclude mineral fibers as a cause of pharyngeal, colorectal and stomach cancer. However there was insufficient evidence to relate asbestos to esophageal cancer.

The IOM, which is quasi-governmental institute, was set upon the task to ‘comprehensively review, evaluate, and summarize the peer-reviewed scientific and medical literature’ on asbestos and the five forms of cancer by the US senate. A debate on legislation to create a $140 billion asbestos-injury compensation fund provoked this study.

The multidisciplinary research committee of the IOM found 35 cohort studies and 15-case-control studies, which analyzed the link between asbestos and cancer of the larynx.

The cohort studies conducted their studies on population drawn from industries such as mining, textiles, and insulation, the report said.

It was found that the number of deaths reported in these studies ranged from one to 36. In addition it was found that in all of the studies in which more than 10 deaths from cancer of the larynx were reported, the relative risk for cancer was greater than one for exposed persons, on comparisons to those without exposure to asbestos.

The control studies revealed only one with a relative risk for cancer below one. Still the overall risk was very similar to that found in the cohort studies: Exposed persons had a relative risk of 1.43 for cancer, compared to non-exposed subjects. The 95% confidence interval ranged from 1.15 to 1.78.

Compiling 10 studies considered to have the best information on exposure as well as combining relative risk in those analyses revealed that the risk of cancer was at 1.21 for exposed subjects, but still significant. The 95% confidence interval ranged from 1.04 to 1.40.

After adjusting for risk factors like tobacco and alcohol use, the relative risk of cancer for an exposed person became 1.18, with a 95% confidence interval from 1.01 to 1.37.

The IOM stated the following biologically plausible reasons for the link between asbestos and laryngeal cancer:

1. The larynx lies anatomically in the direct path of inhaled asbestos fibers.

2. Squamous-cell carcinomas of the lung and larynx are both clinically and histologically similar.

3. Inflammation or damage to the vocal folds could disrupt the smooth flow of inhaled and exhaled air and allow asbestos fibers to build up in the larynx.

4. Cancers of both lung and larynx arise from the respiratory epithelium.

5. Tobacco is the chief risk factor for cancer at both sites.

The report however reports that there was insufficient evidence that asbestos fibers accumulate and persist in the larynx as well as a lack of experimental animal studies to support this

'"/>




Related medicine news :

1. Fibroids unlikely to Turn Cancerous
2. Virus Level could Predict Cervical Cancer Risk
3. Cancer Doctors Okays Controversial Prostate Therapy
4. Potential New Cancer Gene Identified
5. Consensus on "Combination Therapy" for Breast Cancer
6. Cancers of Colon & Rectum linked to Cigarette Smoking
7. Life Saving Cancer Drugs – From Chicken! Possible Says Dolly’ Creatos
8. The Cancer Rumour mill working over time
9. Cancer drugs in development nearly doubled since 1995
10. Radioactive Seeds used in Prostate Cancer treatment can migrate with the body
11. Cancer patients turning to Internet for information
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/24/2016)... ... June 24, 2016 , ... Marcy was in a crisis. Her son James, eight, was out ... family verbally and physically. , “When something upset him, he couldn’t control his emotions,” remembers ... would throw rocks at my other children and say he was going to kill them. ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... micro-osteoperforation for accelerated orthodontic treatment. Dr. Cheng has extensive experience with all areas ... , AcceleDent, and accelerated osteogenic orthodontics. , Micro-osteoperforation is a revolutionary adjunct ...
(Date:6/24/2016)... ... June 24, 2016 , ... People across the U.S. are sharpening their pencils ... an essay contest in which patients and their families pay tribute to a genetic ... 2016 National Society of Genetic Counselors (NSGC) Annual Education Conference (AEC) this September. ...
(Date:6/24/2016)... ... June 24, 2016 , ... Puradigm® & Innovative Solutions ... initiated cultivation and processing operations at its production facility, and opened its first ... is the manufacturer of a complete system of proactive air and surface purification ...
(Date:6/24/2016)... ... June 24, 2016 , ... Venture Construction Group (VCG) sponsors ... on June 20th at the Woodmont Country Club at 1201 Rockville Pike, Rockville, Maryland, ... to helping service members that have been wounded in battle and their families. Venture ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... -- Roche (SIX: RO, ROG; OTCQX: RHHBY) announced that ... PCT (procalcitonin) assay as a dedicated testing solution for ... clearance, Roche is the first IVD company in the ... risk assessment and management. PCT is a ... in blood can aid clinicians in assessing the risk ...
(Date:6/23/2016)... 23, 2016 Capricor Therapeutics, ... a biotechnology company focused on the discovery, development ... patient enrollment in its ongoing randomized HOPE-Duchenne clinical ... 50% of its 24-patient target. Capricor expects the ... quarter of 2016, and to report top line ...
(Date:6/23/2016)... Pa. , June 23, 2016 Bracket ... will launch its next generation clinical outcomes platform, Bracket eCOA ... Meeting held on June 26 – 30, 2016 in ... the first electronic Clinical Outcome Assessment product of its kind ... Booth #715. Bracket eCOA 6.0 is a flexible ...
Breaking Medicine Technology: