Navigation Links
Laryngeal Cancer Added to Asbestos’ Crime Lis

Asbestos that has long been associated with mesothelioma and lung cancer has now been found to cause laryngeal malignancies as well //.

The Indian Institute of Medicine revealed this finding in its report. In addition IOM also concluded that there was ‘suggestive but not sufficient’ evidence to point out conclude mineral fibers as a cause of pharyngeal, colorectal and stomach cancer. However there was insufficient evidence to relate asbestos to esophageal cancer.

The IOM, which is quasi-governmental institute, was set upon the task to ‘comprehensively review, evaluate, and summarize the peer-reviewed scientific and medical literature’ on asbestos and the five forms of cancer by the US senate. A debate on legislation to create a $140 billion asbestos-injury compensation fund provoked this study.

The multidisciplinary research committee of the IOM found 35 cohort studies and 15-case-control studies, which analyzed the link between asbestos and cancer of the larynx.

The cohort studies conducted their studies on population drawn from industries such as mining, textiles, and insulation, the report said.

It was found that the number of deaths reported in these studies ranged from one to 36. In addition it was found that in all of the studies in which more than 10 deaths from cancer of the larynx were reported, the relative risk for cancer was greater than one for exposed persons, on comparisons to those without exposure to asbestos.

The control studies revealed only one with a relative risk for cancer below one. Still the overall risk was very similar to that found in the cohort studies: Exposed persons had a relative risk of 1.43 for cancer, compared to non-exposed subjects. The 95% confidence interval ranged from 1.15 to 1.78.

Compiling 10 studies considered to have the best information on exposure as well as combining relative risk in those analyses revealed that the risk of cancer was at 1.21 for exposed subjects, but still significant. The 95% confidence interval ranged from 1.04 to 1.40.

After adjusting for risk factors like tobacco and alcohol use, the relative risk of cancer for an exposed person became 1.18, with a 95% confidence interval from 1.01 to 1.37.

The IOM stated the following biologically plausible reasons for the link between asbestos and laryngeal cancer:

1. The larynx lies anatomically in the direct path of inhaled asbestos fibers.

2. Squamous-cell carcinomas of the lung and larynx are both clinically and histologically similar.

3. Inflammation or damage to the vocal folds could disrupt the smooth flow of inhaled and exhaled air and allow asbestos fibers to build up in the larynx.

4. Cancers of both lung and larynx arise from the respiratory epithelium.

5. Tobacco is the chief risk factor for cancer at both sites.

The report however reports that there was insufficient evidence that asbestos fibers accumulate and persist in the larynx as well as a lack of experimental animal studies to support this


Related medicine news :

1. Fibroids unlikely to Turn Cancerous
2. Virus Level could Predict Cervical Cancer Risk
3. Cancer Doctors Okays Controversial Prostate Therapy
4. Potential New Cancer Gene Identified
5. Consensus on "Combination Therapy" for Breast Cancer
6. Cancers of Colon & Rectum linked to Cigarette Smoking
7. Life Saving Cancer Drugs – From Chicken! Possible Says Dolly’ Creatos
8. The Cancer Rumour mill working over time
9. Cancer drugs in development nearly doubled since 1995
10. Radioactive Seeds used in Prostate Cancer treatment can migrate with the body
11. Cancer patients turning to Internet for information
Post Your Comments:

(Date:11/25/2015)... ... November 25, 2015 , ... Brillianteen, McGaw YMCA’s ... learning in its 65th Anniversary Brillianteen Revue, scheduled for March 4-6, 2016. Auditions ... 65 years, Brillianteen has been a treasured tradition for numerous families in the ...
(Date:11/25/2015)... ... November 25, 2015 , ... “While riding the bus, ... from Bronx, N.Y. “I thought there had to be a convenient and comfortable way ... , The PROTECTOR enables disabled individuals to safely travel during cold or inclement weather. ...
(Date:11/25/2015)... ... 25, 2015 , ... Castlewood Treatment Center for Eating Disorders, ... as a result of the $20,000 raised at the center’s recent golf ... Club in Eureka, will help individuals who otherwise might not seek treatment for ...
(Date:11/25/2015)... ... November 25, 2015 , ... "When I ... regular bras were incredibly uncomfortable," said an inventor from Bronx, N.Y. "In order ... developed the patent-pending RECOVERY BRA for added comfort and support. The bra is ...
(Date:11/25/2015)... ... November 25, 2015 , ... An unlikely ... resulting in a way for homeless people to have a more dignified and ... new initiative whereby they are repurposing plastic bags into sleeping mats for the ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... November 26, 2015 ... addition of the  "2016 Future Horizons ... Therapeutic Drug Monitoring (TDM) Market: Supplier ... Emerging Opportunities"  report to their offering.  ... announced the addition of the  "2016 ...
(Date:11/26/2015)... 2015 Research and Markets ( ... "2016 Future Horizons and Growth Strategies in the ... Country Segment Forecasts, Competitive Intelligence, Emerging Opportunities" ... --> --> This new 247-page ... therapeutic drug monitoring market, including emerging tests, technologies, ...
(Date:11/25/2015)... DUBLIN , Nov. 25, 2015 /PRNewswire/ ... announced the addition of the "Global ... to their offering. --> ... "Global Brain Monitoring Devices Market 2015-2019" ... Research and Markets ( ) ...
Breaking Medicine Technology: