Navigation Links
Large Study Finds No Need to Screen HIV-positive Patients for Thyroid Disease

Rates of thyroid disease are similar in HIV-positive patients and the general population, according to a large British// study published in the January edition of HIV Medicine. The study’s authors, from London’s Royal Free Hospital, therefore believe that HIV-positive patients do not require thyroid screens as part of their routine HIV care.

HIV infection and treatment with potent antiretroviral therapy have been linked with various hormonal abnormalities, including diabetes and osteoporosis. Recently, some (but not all) studies have suggested a possible link between HIV infection and its treatment with thyroid disease, which can include underactivity (hypothyroidism) and overactivity (hyperthyroidism or thyrotoxicosis).

To clarify further the relationships between thyroid disease, HIV infection and potent anti-HIV therapy, a team at the Royal Free Hospital, London, examined previous thyroid function test results of 1,565 of their patients, 58% of whom were taking anti-HIV treatment.

A total of 39 individuals (2.5%) were found to have overt hypothyroidism and 61 (4%) had subclinical hypothyroidism. Eight people (<1%) had overt hyperthyroidism, five (<1%) had subclinical hyperthyroidism, and 263 (17%) had a non-thyroidal illness that had caused some changes to their thyroid function tests. Repeated measurements were available over three years for 825 patients and only eight new cases of overt thyroid disease occurred. During this period, only one of the group started anti-HIV therapy.

Although patients with overt hypothyroidism tended to be women and older, these associations also hold for the general population. Further analysis found that overt hypothyroidism was also linked with heterosexual risk, use of potent anti-HIV therapy, an AIDS diagnosis, and lower CD4 counts. However, multivariate analysis indicated that the links with markers of progressed disease (AIDS diagnosis and lower CD4 cell counts) were explain ed by the associations with gender and risk group. Thus, they did not detect any variables that were significantly and independently associated with hypothyroidism.

“There is no clear evidence that either subclinical hypothyroidism or subclinical hyperthyroidism should be treated. Recommendations in current guidelines are not to treat, and therefore the value of identifying subclinical disease that progresses slowly (if at all) to a clinical disease is questionable,” the authors write.

Further, the team suggests that, until the results of larger studies are available, “it is wise to be cautious before drawing conclusions regarding thyroid dysfunction and HIV . . . However, our study implies that the prevalence of overt thyroid disease is likely to be similar to that observed in HIV-negative populations and that routine screening of this specific population is not necessary, especially given that patients with overt clinical disease do present clinically and that [thyroid function tests] are a test clinicians have a low threshold for performing.”

Source-Bio-Bio TechnologySRM
'"/>




Related medicine news :

1. The Link Between Larger Birth Weight And Cancer Risk
2. Worlds Largest Cord Blood Bank to be started in India
3. India Has The Oldest And Largest Collection Of Preserved Mosquitoes – Mosquito Museu
4. Fear Of Dengue Epidemic Looms Large: Fever Kills Five in Pakistan
5. Visualization Found To Be Largely Dependent On The Brain
6. Large Scale Study On H5N1 Conducted
7. Large Scale Multiple Sclerosis Vaccine Trial to Be Initiated By PharmaFrontiers
8. Pre-eclampsia Pronounced With Intake of Vitamins in Large Doses
9. Large Ambulances To Handle Obese patients In Vegas
10. Heart Related Problems-The Largest Killers In Andhra Pradesh
11. Large scale culling of poultry effected at Cote dIvoire following bird flu outbreak.
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/29/2016)... ... April 29, 2016 , ... In an article published ... her enthusiasm for Botox and lip injections, which she underwent in order to feel ... Valley Music and Arts Festival. The article explains that Ms. Mirmelli’s situation is not ...
(Date:4/29/2016)... ... April 29, 2016 , ... Our bodies are bombarded daily ... confront and deal with these stressors is to adopt a more healthful diet, but ... you. Risa Groux, a certified Holistic Nutritionist and the creator of the Newport Beach ...
(Date:4/29/2016)... Sterling, VA (PRWEB) , ... April 29, 2016 ... ... Americans with student loans more flexibility in repaying their loans, more information about ... at a time when total outstanding student loan debt, including federal and private ...
(Date:4/29/2016)... ... April 29, 2016 , ... Spine Team Texas, a comprehensive ... to announce one of their physicians has been invited to be a featured speaker ... Family Practice Review conference on April 30, 2016. , Dr. R. Scott McPherson, ...
(Date:4/29/2016)... ... 2016 , ... The Gluten-Free Certification Program (GFCP), in partnership ... launch of the GFCP Scoop in response to consumer demand for ... GFCP Scoop site is to keep the gluten-free community updated about ...
Breaking Medicine News(10 mins):
(Date:4/28/2016)...   Acsis , a leading provider of supply ... research and advisory firm IDC has named it a ... Pharmaceutical Track and Trace Software 2016 Vendor Assessment (doc ... of the capabilities and business strategies of 10 vendors ... Logo - http://photos.prnewswire.com/prnh/20160427/360791LOGO ...
(Date:4/27/2016)... BASEL , Schweiz, April 27, 2016 ... des Sachs CEO Forums in Zürich ... Phase-II-Studie ihres führenden Wirkstoffkandidaten STR001 zur Erhaltung ... (CI) eingesetzt wurde, bekannt. Für die umfassende ... Deutschland und Frankreich angeworben. STR001 wird während ...
(Date:4/27/2016)... April 27, 2016   Zillion Group ... health technology platform, which specializes in live video ... scalable digital products, Zillion enables companies to realize ... consumers to take control of their health. ... conferencing – including one-to-one, group and webcast scheduled ...
Breaking Medicine Technology: