Navigation Links
Lack of STAT1 -an Immune Protein, Pack Liver Infection Cure

proteins are responsible for the production of interferon gamma, an important protein that helps launch a full-blown immune system attack against foreign pathogens.

A group of mice with both STAT1 and T-bet genes intact served as a control.

About two weeks after infection, the researchers began measuring the number of L. donovani parasites in the animals’ livers.

The pathogen went wild in the mice that lacked T-bet – the researchers found thousands upon thousands of the parasites in the livers of these animals.

Yet there were next to no parasites in the mice without STAT1.

‘Two weeks after infection, the mice without STAT1 had 25-fold fewer parasites in their liver tissue than the normal mice, and about 100-fold fewer parasites than the mice without T-bet,’ Satoskar said. ‘Visceral leishmaniasis never developed in the animals without STAT1 – the parasites weren’t able to establish an infection in the animals’ livers and spleens.’

The researchers also measured parasite levels in the livers two months after infection. Again, levels were quite high in the mice without T-bet, while normal mice and mice without STAT1 showed no sign of the disease.

While the normal mice weren’t sick – they showed no physical signs of having leishmaniasis, such as inflammation of the liver and spleen – Satoskar said the parasite was still in their systems.

‘Once infected, the parasite never goes away completely,’ Satoskar said. ‘It’s always hiding somewhere.’

Ironically, L. donovani thrives in the liver and spleen by infecting the very cells that the immune system uses to rid the parasite from the body. These cells are called macrophages – a kind of garbage collector for the immune system, as they clean out everything from red blood cells that have died to infectious pathogens. But enough L. donovani parasites can overtake a macrophage’s ability to clean up.

‘L. donovani infection failed to
'"/>




Page: 1 2 3

Related medicine news :

1. Immune cells halt round in space
2. Immune function could benefit from exercise
3. Reviving the Immune System
4. Wrestling found To Be Good for the Immune System
5. Immune Boost With LHRH To Help Cancer And Transplant Patients
6. Researchers Find Out The Cause Of Immune Attacks Behind Hearing Loss
7. Block Immune System Chemical For Treating Asthma
8. Immune Response Of Human Beings Can Be Re-energized
9. Weizmann Institute of Science says Immune Cells Could Help Maintain Brain Function
10. Antidepressant drugs interacts with Immune cells
11. Specific Immune Mechanism against DNA viruses
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Lack STAT1 Immune Protein Pack Liver Infection Cure

(Date:7/12/2014)... Dennis Thompson HealthDay Reporter ... way to guarantee that a surgical technique used to grind ... increase the risk of spreading cancer to other parts of ... advisory panel to the Food and Drug Administration also said ... power morcellation -- should sign a written consent stating that ...
(Date:7/12/2014)... July 12, 2014 Demand Response Management ... considerable benefits in reducing the imbalance between energy supply ... appliances have been rolled out (due to increasing pressure ... (AMI). This helps in controlling residential appliances and thermostats ... in the North American region, and with government mandates ...
(Date:7/12/2014)... 12, 2014 Tylenol lawsuits ( ... move forward in the federal multidistrict litigation underway ... Bernstein Liebhard LLP reports. According to a filing ... F. Stengel has ordered the deposition of a ... found that the witness’s testimony concerning the marketing ...
(Date:7/12/2014)... SATURDAY, July 12, 2014 (HealthDay News) -- Burn injuries increase ... and outdoor grills, say burn experts. Among those most vulnerable ... among the most vulnerable and often get burned by putting ... Gamelli, director of the burn unit at Loyola University ... release. "The old adage of ,When you play with ...
(Date:7/12/2014)... 2014 “After my mom’s stroke, she loss the ... and loss the use of his left side. Eating became a ... to help people like them enjoy eating again,” said an inventor, ... the PATRICIA CAROL HALL PLATE (P C H PLATE). , The ... ergonomic way to eat for individuals who suffer from stroke, experience ...
Breaking Medicine News(10 mins):Health News:FDA Advisers Weigh Risks of Procedure for Removal of Uterine Fibroids 2Health News:FDA Advisers Weigh Risks of Procedure for Removal of Uterine Fibroids 3Health News:North America Demand Response Management System Worth $12,522.4 Million by 2019 - New Report by MicroMarket Monitor 2Health News:North America Demand Response Management System Worth $12,522.4 Million by 2019 - New Report by MicroMarket Monitor 3Health News:North America Demand Response Management System Worth $12,522.4 Million by 2019 - New Report by MicroMarket Monitor 4Health News:Tylenol Lawsuit News: U.S. District Judge Overseeing Federal Tylenol Liver Damage Litigation Orders Deposition of Former McNeil President, Bernstein Liebhard LLP Reports 2Health News:Tylenol Lawsuit News: U.S. District Judge Overseeing Federal Tylenol Liver Damage Litigation Orders Deposition of Former McNeil President, Bernstein Liebhard LLP Reports 3Health News:Tylenol Lawsuit News: U.S. District Judge Overseeing Federal Tylenol Liver Damage Litigation Orders Deposition of Former McNeil President, Bernstein Liebhard LLP Reports 4Health News:Burn Injuries More Common in Summer 2
... Cape Cod is synonymous with a surge of tourists, ... (Marine Biological Laboratory). For more than a century, researchers ... the world to immerse themselves in biological discovery. Many ... for study and the wealth of experts who gather ...
... crash data in public policy effort to boost safety , , ... the deadliest road in your town or your route to ... increase public awareness of the need to drive safely. ... in Rural Safety (CERS) developed www.saferoadmaps.org, so you can simply ...
... Measuring a woman,s bone mineral density can provide additional ... risk of developing breast cancer. That is the ... 1, 2008 issue of CANCER , a peer-reviewed ... suggest that incorporating bone mineral density tests with current ...
... TEM Counseling LLC launches new website offering convenient http://www.terrimilen.com ... clients in the comfort of their own home or office. ... ... an effort to provide clients with an alternative to traditional therapy ...
... following is a,transcript of the radio address by President Bush ... Congress voted to expand a,vital program that is saving lives ... also known as PEPFAR. I thank members of,Congress from both ... this important bill, and I will be honored to sign ...
... Mexican farm, FDA announces , , FRIDAY, July 25 ... the first big clue in the nationwide salmonella outbreak, ... had been definitively traced to a farm in Mexico. ... all-clear to jalapeno and serrano peppers grown in the ...
Cached Medicine News:Health News:LabBits: A media tip sheet from the MBL in Woods Hole 2Health News:LabBits: A media tip sheet from the MBL in Woods Hole 3Health News:LabBits: A media tip sheet from the MBL in Woods Hole 4Health News:Researchers Map America's Deadliest Roads 2Health News:Hip bone density helps predict breast cancer risk 2Health News:Online Counseling and Life Coaching Practice Launches New Website 2Health News:Radio Address by President Bush to the Nation 2Health News:Radio Address by President Bush to the Nation 3Health News:Mexican Peppers ID'd as Salmonella Culprits 2Health News:Mexican Peppers ID'd as Salmonella Culprits 3
(Date:7/11/2014)... , July 11, 2014 Patient engagement ... and, consequently, organizations are turning to an assortment ... As part of this evolving approach to ... educate, communicate and engage patients throughout their experiences ... patient empowerment. By mapping the patient journey and ...
(Date:7/11/2014)... 11, 2014 According to ... Composition of Material, Application (Healthcare, Homeland security, Industrial ... (Personal Instrument, Hand-Held Instruments, Fixed, and Installed Instruments) ... 2013 - 2020", published by MarketsandMarkets, the Scintillator Market is ... from 2014 to 2020, and reach $479.16 Million ...
(Date:7/11/2014)... , July 11, 2014 ... at 4,396.20, down 0.52%, the Dow Jones Industrial Average finished ... closed at 1,964.68, down 0.41%. The losses were broad based ... negative. The S&P 500 Health Care Sector Index ended the ... 2.75% in the last one month. Investor-Edge has initiated coverage ...
Breaking Medicine Technology:New Study Uses Six-Step Patient Journey as Framework for Consumer-Focused Marketing Opportunities 2Scintillator Market will be worth $479.16 Million by 2020 2Scintillator Market will be worth $479.16 Million by 2020 3Scintillator Market will be worth $479.16 Million by 2020 4Health Care Equipment Equities Movers and Shakers -- Research on Covidien, Baxter, DexCom, and Boston Scientific 2Health Care Equipment Equities Movers and Shakers -- Research on Covidien, Baxter, DexCom, and Boston Scientific 3Health Care Equipment Equities Movers and Shakers -- Research on Covidien, Baxter, DexCom, and Boston Scientific 4
... Margaret A. Hamburg, M.D., said today she is revoking ... Avastin (bevacizumab) after concluding that the drug has not ... use. (Logo: http://photos.prnewswire.com/prnh/20090824/FDALOGO) Avastin will ... for certain types of colon, lung, kidney and brain ...
... -- China Medical Technologies, Inc. (the "Company") (Nasdaq: CMED ), ... results for the second fiscal quarter ended September 30, 2011 ("2Q FY2011") ... Six M onths Ended ... Three   Months   EndedSeptember   ...
Cached Medicine Technology:FDA Commissioner announces Avastin decision 2FDA Commissioner announces Avastin decision 3China Medical Technologies Reports Second Fiscal Quarter Financial Results 2China Medical Technologies Reports Second Fiscal Quarter Financial Results 3China Medical Technologies Reports Second Fiscal Quarter Financial Results 4China Medical Technologies Reports Second Fiscal Quarter Financial Results 5China Medical Technologies Reports Second Fiscal Quarter Financial Results 6China Medical Technologies Reports Second Fiscal Quarter Financial Results 7China Medical Technologies Reports Second Fiscal Quarter Financial Results 8China Medical Technologies Reports Second Fiscal Quarter Financial Results 9China Medical Technologies Reports Second Fiscal Quarter Financial Results 10China Medical Technologies Reports Second Fiscal Quarter Financial Results 11China Medical Technologies Reports Second Fiscal Quarter Financial Results 12China Medical Technologies Reports Second Fiscal Quarter Financial Results 13China Medical Technologies Reports Second Fiscal Quarter Financial Results 14China Medical Technologies Reports Second Fiscal Quarter Financial Results 15China Medical Technologies Reports Second Fiscal Quarter Financial Results 16China Medical Technologies Reports Second Fiscal Quarter Financial Results 17China Medical Technologies Reports Second Fiscal Quarter Financial Results 18China Medical Technologies Reports Second Fiscal Quarter Financial Results 19China Medical Technologies Reports Second Fiscal Quarter Financial Results 20China Medical Technologies Reports Second Fiscal Quarter Financial Results 21China Medical Technologies Reports Second Fiscal Quarter Financial Results 22China Medical Technologies Reports Second Fiscal Quarter Financial Results 23China Medical Technologies Reports Second Fiscal Quarter Financial Results 24
The PC4200h is the largest capacity platelet incubator available. It features a built-in agitator with a capacity of 396 random bags (132 apheresis)....
The PC4200i is the largest capacity platelet incubator available. It features a built-in agitator with a capacity of 396 random bags (132 apheresis)....
... Platelet incubators hold rotators ... Incubator temperature can be set ... from 15C to 40C (59F ... 0.5C from top to bottom. ...
ELISA for detection of Anti-Gliadin IgA....
Medicine Products: