Navigation Links
Lack Of Estrogen In Brain Tissue Of Women Can Lead To Alzheimer's

It has been found from autopsy studies that women with Alzheimer’s disease have low levels of the sex hormone estrogen in their brain tissue than women with a sound mental health. // The research has been conducted by Dr. Rena Li and colleges at the University of Chicago.

Previous studies conducted on animal models have already revealed that deficiency of estrogen in the brain tissue can speed up the build up of ‘plaque’, which is a common characteristic of the disease.

An analysis of the serum estrogen levels revealed lower levels of the hormone in both patients with Alzheimer’s and control subjects. Hence no correlation between the serum estrogen levels and the onset of the disease could be identified.

It has therefore been concluded that deficiency of estrogen in the brain rather than blood estrogen deficiency could be more specific in the pathogenesis behind Alzheimer’s. This is supported by the fact that the brain cannot manufacture estrogen.

In order to assess the effect of reduced levels of estrogen in the brain on the onset and severity of the disease, the researchers developed mice that mimicked Alzheimer’s disease through specialized breeding techniques. In addition, it lacked the capacity to synthesize estrogen as well.

Animals that were thus produced had reduced levels of estrogen in the brain and had a much earlier onset of plaque build up. To confirm that brain estrogen levels plays a significant role in the disease process, mice that underwent ovary removal was examined for the development of estrogen deficient brain disease.

As anticipated, only mice with deficient levels of estrogen in the brain developed the disease. The above finding perhaps serves to explain the failure of development of Alzheimer’s in all post-menopausal women. It has further been hypothesized that certain specific genetic mechanisms could be responsible for the observed variability in the onset of the disease.

Most importantly, the results of the present study have highlighted the need for development of an estrogen formulation that can cross the blood brain barrier to be effective against the disease. The research team is currently assessing a number of natural estrogen products for the above-mentioned transport potential.


'"/>




Related medicine news :

1. Estrogen lowers cancer risk
2. Estrogen Does Not Prevent Recurrent Strokes
3. Herbs With Estrogen Action Aggravate Cancer Risk
4. Osteoarthritis and Estrogen are connected
5. Estrogen Patch is Safer than Pills for Heart
6. Estrogen in Food Reduces Cancer Risk
7. Estrogen Found To Protect the Colon Against Cancer
8. The Side Effects Of Estrogen Therapy
9. The Effects Of Estrogen Therapy
10. A Likely Use For Estrogen Therapy
11. Preventing Colon Cancer With Estrogen
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/26/2016)... ... June 26, 2016 , ... Brent Kasmer, a legally blind and certified personal trainer is helping ... fitness app. The fitness app plans to fix the two major problems leading the fitness ... size fits all type program , They don’t eliminate all the reasons people ...
(Date:6/25/2016)... , ... June 25, 2016 , ... The temporary closing of Bruton Memorial Library on ... Observer , brings up a new, often overlooked aspect of head lice: the parasite’s ability ... fumigation is not a common occurrence, but a necessary one in the event that lice ...
(Date:6/25/2016)... ... June 25, 2016 , ... ... non-athletes recover from injury. Recently, he has implemented orthobiologic procedures as a method ... —Johnson is one of the first doctors to perform the treatment. Orthobiologics are ...
(Date:6/24/2016)... ... ... Those who have experienced traumatic events may suffer from a complex set ... drug or alcohol abuse, as a coping mechanism. To avoid this pain and suffering, ... traumatic event. , Trauma sufferers tend to feel a range of emotions, from depression, ...
(Date:6/24/2016)... ... June 24, 2016 , ... Global law firm Greenberg Traurig, ... Elite. The attorneys chosen by their peers for this recognition are considered among the ... Traurig Shareholders received special honors as members of this year’s Legal Elite Hall of ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... , June 27, 2016  VMS Rehab Systems, Inc. ... will take whatever measures required to build a strong ... which is currently listed on the OTC Markets-pink current ... Chairman and CEO, "We are seeing an anomaly in ... understand, not only by the Company, but shareholders and ...
(Date:6/24/2016)... 24, 2016   Bay Area Lyme Foundation ... Dean Center for Tick Borne Illness , Harvard ... MIT Hacking Medicine, University of California, Berkeley, and ... the five finalists of Lyme Innovation , ... than 100 scientists, clinicians, researchers, entrepreneurs, and investors ...
(Date:6/24/2016)... and SAN CLEMENTE, Calif. , June 24, 2016 ... mobile pulmonary function testing company, is now able to perform sophisticated ... by ndd Medical Technologies , Inc. Patients ... hospital-based labs.  Thanks to ndd,s EasyOne PRO ® , ARL patients ... get any needed testing done in the comfort of her own ...
Breaking Medicine Technology: