Navigation Links
Key Gene Controlling Eye Lens Development Identified

ormal thickening, an initial critical step in lens formation.

“Our discovery helps to better unravel the regulatory pathway that controls normal lens formation,” said the paper’s senior author, Guillermo Oliver, Ph.D., a member of the St. Jude Genetics and Tumor Cell Biology department. “Specifically, it puts the Six3 gene at the top of the genetic cascade that controls the development of the lens. Understanding the early steps leading to lens formation will help us determine what goes wrong in disorders in which the lens does not form, or forms abnormally. That kind of information is often the first step in designing both preventive and treatment strategies for congenital diseases.”

The St. Jude team further showed that the proteins coded for by Six3 are present in the PLE before those coded by Pax6. This was evidence that production of Pax6 proteins in that region of the head starts after Six3 proteins are made, further supporting the idea that the Six3 gene controls the Pax6 gene. The researchers also demonstrated that the Six3 protein directly controls the expression of the Pax6 gene by binding to some of the DNA regions that regulate Pax6 activity.

“Our work confirms the early and vital role Six3 plays in the overall development of the eye, and gives us important insights into the interplay of genes during this time,” said Wei Liu, Ph.D., a postdoctoral fellow in Oliver’s laboratory. Lui is first author of the paper.

Source-Newsise
SRM
'"/>




Page: 1 2

Related medicine news :

1. Controlling Asthma during Pregnancy
2. Controlling Allergies Before They Start
3. Controlling Asthma
4. Controlling High Blood Can Reduce Eye Problems In Diabetics
5. Herb Found To Be Effective In Controlling Blood Sugar Levels
6. Diuretics More Effective In Controlling High Blood Pressure
7. Solution For Controlling The Raising Health Costs
8. Stomach Hormone to Aid in Controlling Appetite
9. Research Identifies Osteoporosis Controlling Protein
10. Researchers Make a Major Strategic Breakthrough in Controlling the AIDS Virus
11. Health Experts In Australia Toy With The Idea Of Surgery for Controlling Obesity In Teenagers
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Key Gene Controlling Eye Lens Development Identified

(Date:9/30/2014)... (PRWEB) September 30, 2014 Barbara Williamson ... her amazing memoir "An Extraordinary Life: Love, Sex ... “the messiah of sex,” of the highly successful and ... 1960s and early ‘70s, the couple started what became ... The clothing-optional, alternate-lifestyle Sandstone Retreat was outrageously popular, with ...
(Date:9/30/2014)... In a move that will ... capture and management functions for sponsors, Synergy Research ... (EDC) system. ClinCapture offers advanced out-of-the-box features that ... clinical trial data and avoid errors and duplications. ... the leading clinical research organization in the Russian ...
(Date:9/30/2014)... 2014 Computer Resources of America, ... based in New York City, has been awarded ... to transform, manage, and support the IT environment ... a leading provider of innovative services that enable ... The contract will cover the four NY-metro ...
(Date:9/30/2014)... September 30, 2014 Miraca Life Sciences ... present eight research posters at the annual meeting of ... will hold its Annual Scientific Meeting and Postgraduate Course ... hall, staff from Miraca Life Sciences will be at ... Clinical Case Challenge. , The research posters for ACG ...
(Date:9/30/2014)... Bibliomotion is proud to announce the release of ... Age by Frank Guglielmo and Sudhanshu Palsule ... apply their leadership coaching experience to introduce Social Leadership – ... behaviors that leaders must adopt in order to thrive in ... a review of The Social Leader in Dialogue Reviews. , ...
Breaking Medicine News(10 mins):Health News:The Autobiography "An Extraordinary Life: Love, Sex and Commitment" Embraces Healthy Sexual Behavior 2Health News:The Autobiography "An Extraordinary Life: Love, Sex and Commitment" Embraces Healthy Sexual Behavior 3Health News:Synergy Research Group Opts for Clinovo 2Health News:Synergy Research Group Opts for Clinovo 3Health News:CRA Awarded Managed Services Contract for Large NYC Nonprofit 2Health News:Miraca Life Sciences Research Institute to Present Eight GI Pathology Research Studies at Annual Meeting of American College of Gastroenterologists 2Health News:The Social Leader: new Bibliomotion book redefines leadership for the Social Age 2Health News:The Social Leader: new Bibliomotion book redefines leadership for the Social Age 3Health News:The Social Leader: new Bibliomotion book redefines leadership for the Social Age 4Health News:The Social Leader: new Bibliomotion book redefines leadership for the Social Age 5Health News:The Social Leader: new Bibliomotion book redefines leadership for the Social Age 6
... 27 (HealthDay News) -- Arizona Congresswoman Gabrielle Giffords began ... forward for the lawmaker who was shot in the ... Memorial Hermann Hospital could last several months. As a ... insert a valve into her breathing tube, the ...
... January 27, 2011 Screening patients in the intensive ... cost savings for the whole hospital, according to a ... the February issue of the American Journal of ... the Association for Professionals in Infection Control and Epidemiology. ...
... , THURSDAY, Jan. 27 (HealthDay News) -- Only 42 ... and can therefore be categorized as "great sleepers," according to ... Poll" found that great sleepers get an average of about ... sleeper gets an average of seven hours and nine minutes ...
... News) -- Electroshock devices, currently classified by the U.S. Food ... severe depression, could be downgraded to medium risk this year. ... to discuss reclassifying the devices, which would pave the way ... illnesses. , , A medium-risk classification would put the devices ...
... continue dating a girlfriend who has cheated on them with ... according to new research from a University of Texas at ... are more likely to continue dating a man who has ... homosexual affair. The study, published last month in the ...
... in China have demonstrated interferon-alpha (IFN-a) is associated with ... erythematosus (SLE). For the first time, IFN-a priming was ... crucial step in plaque build-up. This activation of the ... atherosclerosis risk in SLE. Full findings of this novel ...
Cached Medicine News:Health News:Rep. Giffords' Intensive Rehab Under Way 2Health News:Rep. Giffords' Intensive Rehab Under Way 3Health News:Study finds MRSA screening saves hospitals money 2Health News:Loving Your Bedroom May Be Key to Good Sleep 2Health News:FDA May Ease Up on Electroshock Devices 2Health News:FDA May Ease Up on Electroshock Devices 3Health News:Men more likely to stick with girlfriends who sleep with other women than other men 2Health News:Researchers uncover link to increased atherosclerosis risk in lupus patients 2
(Date:9/29/2014)... 29, 2014 Pharmaceutical Care Management Association (PCMA) ... policy solutions that could reduce prescription fraud and abuse ... " Prescription Opioid Abuse: Fighting Back on Many Fronts ... PCMA. The briefing featured several government ... abuse and fraud. The Centers for Disease Control and ...
(Date:9/29/2014)... LAKE CITY , Sept. 29, 2014 /PRNewswire/ ... has scheduled a conference call for investors today ... for the quarter and year ended June 30, ... in participating is (800) 771-7941. Dynatronics ... soft goods and supplies, treatment tables and rehabilitation ...
(Date:9/29/2014)... YORK , Sept. 29, 2014 ... Summary GlobalData,s new report, "EU5 Esophagoscopes ... market data on the EU5 Esophagoscopes & Gastroscopes ... US dollars, volume (in units) and average prices ... Video Esophagoscopes, Flexible Non-Video (Fibre) Gastroscopes and Flexible ...
Breaking Medicine Technology:PCMA: How Congress Can Fight Prescription Drug Fraud and Abuse 2EU5 Esophagoscopes & Gastroscopes Market Outlook to 2020 2EU5 Esophagoscopes & Gastroscopes Market Outlook to 2020 3
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: