Navigation Links
Kaposi Sarcoma Arise from Multiple Cells

According to a study published in the Journal of the National Cancer Institute, Kaposi sarcoma is unique among cancers because most tumors grow from a small number of different cells , whereas nearly all other cancers arise from a single cell.

Kaposi sarcoma, which is often associated with AIDS, primarily affects the skin. But as the disease progresses, it can move to the lymph nodes and internal organs as well.

Renan Duprez, Ph.D., of the Institut Pasteur in Paris and colleagues performed the largest study to date on the origins of advanced Kaposi sarcoma. Biopsies from 98 Kaposi sarcoma patients were analyzed using molecular diagnostic techniques to compare the viral DNA of the tumors, which often contain human herpesvirus 8.

The researchers found evidence that nearly 80% of the tumors arose independently from multiple cells. They concluded that few Kaposi sarcoma tumors originate from a single cell and that Kaposi sarcoma, especially in its advanced form, is not true metastatic cancer.

In an accompanying editorial, Parkash Gill, M.D., of Norris Cancer Hospital and Research Institute in Los Angeles recommends what should come next in Kaposi sarcoma research.

With some resolution as to the clonal nature of [Kaposi sarcoma] of the skin and lymph node, similar analysis remains to be done for visceral [Kaposi sarcoma], which can be more invasive leading at times to catastrophic organ dysfunction and even death.

It is also not known if the clonal [Kaposi sarcoma] lesions identified in this study were more aggressive and less likely to respond to therapy, Gill writes.

Contact: Article: Antoine Gessain, agessain@pasteur.fr, +33 0145688937 Editorial: Parkash Gill, parkashg@hsc.usc.edu, (323) 865-3909


'"/>




Page: 1

Related medicine news :

1. Kissing can cause Kaposi’s Sarcoma in AID
2. Virus Causing Kaposis Sarcoma Discovered
3. Risk Of Soft Tissue Sarcomas In Hereditary Retinoblastoma Survivors
4. Pazopanib Shows Positive in Advanced Renal Carcinoma, Ovarian Cancer and Soft Tissue Sarcoma
5. Hyperthermia With Chemotherapy Improves Sarcoma Healing
6. Naked DNA Vaccination May Conquer Arthritis and Multiple Sclerosis
7. Multiple organ disease cured by genes
8. Adult stem cells in treatment for Multiple sclerosis (MS)
9. Life Quality For Patients With Multiple Sclerosis
10. Effective Pain Relief For Patients Suffering From Multiple Sclerosis
11. The Link Between Hepatitis B Vaccine And Multiple Sclerosis Questioned
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/25/2016)... ... June 25, 2016 , ... Experts from the American ... Annual Research Meeting June 26-28, 2016, at the Hynes Convention Center in Boston. ... including advance care planning, healthcare costs and patient and family engagement. , AIR ...
(Date:6/25/2016)... California (PRWEB) , ... June 25, 2016 , ... "With ... fit their specific project," said Christina Austin - CEO of Pixel Film Studios. ... customizable and all within Final Cut Pro X . Simply select a ProHand ...
(Date:6/25/2016)... Oklahoma City, Oklahoma (PRWEB) , ... June 25, ... ... to helping both athletes and non-athletes recover from injury. Recently, he has implemented ... for the Oklahoma City area —Johnson is one of the first doctors to ...
(Date:6/24/2016)... ... June 24, 2016 , ... A recent article published June ... with. The article goes on to state that individuals are now more comfortable seeking ... common operations such as calf and cheek reduction. The Los Angeles area medical group, ...
(Date:6/24/2016)... ... June 24, 2016 , ... Marcy was in a crisis. Her son James, eight, ... at his family verbally and physically. , “When something upset him, he couldn’t control his ... it. He would throw rocks at my other children and say he was going to ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... 2016  Astellas today announced the establishment of Astellas Farma Colombia (AFC), a new affiliate with operations headquartered in ... America . ... ... ... ...
(Date:6/23/2016)... PRINCETON, N.J. , June 23, 2016  Guerbet ... of Premier Inc.,s Supplier Horizon Award . ... this year, Guerbet was recognized for its support of ... value creation through clinical excellence, and commitment to lower ... delighted to receive this recognition of our outstanding customer ...
(Date:6/23/2016)... -- Research and Markets has announced the ... (United States, China, Japan, Brazil, United Kingdom, Germany, France, ... Surgical Procedure Volumes: ... provides surgical procedure volume data in a geographic context. ... analysis of growth drivers and inhibitors, including world population ...
Breaking Medicine Technology: