Navigation Links
Kaposi Sarcoma Arise from Multiple Cells

According to a study published in the Journal of the National Cancer Institute, Kaposi sarcoma is unique among cancers because most tumors grow from a small number of different cells , whereas nearly all other cancers arise from a single cell.

Kaposi sarcoma, which is often associated with AIDS, primarily affects the skin. But as the disease progresses, it can move to the lymph nodes and internal organs as well.

Renan Duprez, Ph.D., of the Institut Pasteur in Paris and colleagues performed the largest study to date on the origins of advanced Kaposi sarcoma. Biopsies from 98 Kaposi sarcoma patients were analyzed using molecular diagnostic techniques to compare the viral DNA of the tumors, which often contain human herpesvirus 8.

The researchers found evidence that nearly 80% of the tumors arose independently from multiple cells. They concluded that few Kaposi sarcoma tumors originate from a single cell and that Kaposi sarcoma, especially in its advanced form, is not true metastatic cancer.

In an accompanying editorial, Parkash Gill, M.D., of Norris Cancer Hospital and Research Institute in Los Angeles recommends what should come next in Kaposi sarcoma research.

With some resolution as to the clonal nature of [Kaposi sarcoma] of the skin and lymph node, similar analysis remains to be done for visceral [Kaposi sarcoma], which can be more invasive leading at times to catastrophic organ dysfunction and even death.

It is also not known if the clonal [Kaposi sarcoma] lesions identified in this study were more aggressive and less likely to respond to therapy, Gill writes.

Contact: Article: Antoine Gessain, agessain@pasteur.fr, +33 0145688937 Editorial: Parkash Gill, parkashg@hsc.usc.edu, (323) 865-3909


'"/>




Page: 1

Related medicine news :

1. Kissing can cause Kaposi’s Sarcoma in AID
2. Virus Causing Kaposis Sarcoma Discovered
3. Risk Of Soft Tissue Sarcomas In Hereditary Retinoblastoma Survivors
4. Pazopanib Shows Positive in Advanced Renal Carcinoma, Ovarian Cancer and Soft Tissue Sarcoma
5. Hyperthermia With Chemotherapy Improves Sarcoma Healing
6. Naked DNA Vaccination May Conquer Arthritis and Multiple Sclerosis
7. Multiple organ disease cured by genes
8. Adult stem cells in treatment for Multiple sclerosis (MS)
9. Life Quality For Patients With Multiple Sclerosis
10. Effective Pain Relief For Patients Suffering From Multiple Sclerosis
11. The Link Between Hepatitis B Vaccine And Multiple Sclerosis Questioned
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/8/2016)... ... February 08, 2016 , ... Remember the old saying “rub some ... to Perry A~, author of “Calcium Bentonite Clay” the health benefits of integrating clay ... and detoxifying the body. , A former motivational speaker, Perry A~ has since dedicated ...
(Date:2/8/2016)... ... 2016 , ... Discover the Rocky Mountain region’s longest running and impressive garden ... Attendees also get to see the most incredible gardens and home improvement experts that ... the Colorado Convention Center - 700 14th St. Denver CO, is an exciting event ...
(Date:2/8/2016)... ... February 08, 2016 , ... TopConsumerReviews.com recently awarded their highest five-star rating ... Moles are derived from a cluster of melanin when exposed to sunlight. Although most ... create a lifetime of embarrassment. Historically, mole removal has involved a painful, ...
(Date:2/8/2016)... CA (PRWEB) , ... February 08, 2016 , ... The ... held annually in this country. The AutismOne 2016 Conference, which is being held May ... they often won’t hear elsewhere about helpful interventions and causes of chronic illness in ...
(Date:2/7/2016)... Orion, Clarkston, Metamora, Michigan (PRWEB) , ... February 07, 2016 , ... ... Friday in recognition of National Wear Red Day. National Wear Red Day is ... and stroke in women. Heart disease and stroke cause 1 in 3 deaths among ...
Breaking Medicine News(10 mins):
(Date:2/8/2016)... , Feb. 8, 2016  Avista Pharma Solutions ... Eric Setzer as Chief Financial Officer (CFO). Mr. Setzer ... years of experience in various roles within growing technology ... he served as the Executive Director of Finance at ... Raleigh, NC . Previously, Mr. Setzer ...
(Date:2/8/2016)... DUBLIN , Feb. 8, 2016 /PRNewswire/ ... announced the addition of the "Label-Free ... Global Forecasts to 2020" report to ... has announced the addition of the ... - Global Forecasts to 2020" report ...
(Date:2/8/2016)... , Feb. 8, 2016  Unilife Corporation ("Unilife" or "Company") ... of injectable drug delivery systems, today announced that it will ... ended December 31, 2015 after market close on February 9, ... conference call to discuss these financial results.    ... --> About Unilife Corporation ...
Breaking Medicine Technology: