Navigation Links
KADIAN Efficacy Not Affected by Alcohol Consumption

The results of Phase IV study of KADIAN ? (morphine sulfate extended-release) Capsules have been released by Alpharma Inc. (NYSE: ALO), a leading pharmaceutical company. It reveals that the pharmacokinetics// of the long-acting opioid are not significantly affected by the consumption of alcohol.

Results of this pharmacokinetic study, which Alpharma conducted in response to a request by the U.S. Food and Drug Administration (FDA) to assess whether alcohol interferes with the extended-release mechanism of action in long-acting opioids, were presented yesterday at the 23rd Annual Meeting of the American Academy of Pain Medicine (AAPM) in New Orleans, LA.

"This study demonstrated that the extended-release properties of KADIAN? were maintained even in the presence of a significant quantity of alcohol," says Joseph Stauffer, DO, Vice President, Clinical Research & Medical Affairs, Alpharma Pharmaceuticals Division Inc. "We believe this information is valuable for doctors in their assessment of KADIAN?, and we will continue to educate clinicians and patients about the appropriate use of KADIAN? for moderate-to-severe chronic pain. Like most medications, KADIAN? should not be taken with alcohol."

These results indicate that the concomitant use of tested levels of alcohol with KADIAN? has no significant impact on mean morphine blood levels or the timing of morphine release.

The company has provided these data to the FDA and any future labeling implications will be determined following the completion of its review.

Study Design
In the open-label, single-dose, three-way crossover pharmacokinetic drug interaction study, 32 healthy adult male volunteers, 21 to 40 years of age, were randomized to receive:

KADIAN? 100 mg with ethanol (8 ounces of 40 percent alcohol) while fasting;

KADIAN? 100 mg with ethanol (8 ounces of 40 percent alcohol) while fed;

KADIAN? 100 mg with 8 oun
'"/>




Page: 1 2

Related medicine news :

1. Efficacy Of Meningitis C Vaccine
2. The Efficacy Of Allergy Shots Questioned
3. The Efficacy Of Newer Stents Questioned
4. The Efficacy Of Hormone Replacement Therapy Studied
5. Ambiguous Efficacy Of Opioid Drugs In Chronic Inflammatory Joint Pain Relief
6. Efficacy of fish oil supplements in pregnancy.
7. Efficacy of Omega 3 Fatty Acids Needs Wider Perspective
8. Thailand To Test Efficacy Of Stem Cell Technology
9. Efficacy Of Sports-Formulated Jelly Beans In Warding Off Fatigue To Be Studied
10. Indian And Chinese Doctors Join Together To Prove The Efficacy Of Herbal Drugs
11. New Study Shows Efficacy of AROMASIN on Early Breast Cancer
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: KADIAN Efficacy Not Affected Alcohol Consumption

(Date:7/4/2015)... ... 04, 2015 , ... Chronic Neck Pain. Neck pain is no ... in the neck. Another 19% suffer from head, migraine, or facial pain, in some ... 45% of American workers must deal with neck pain. Strategies for mitigating ...
(Date:7/4/2015)... ... July 04, 2015 , ... Tyler Boden, Project Developer of ... expertise from the North American Board of Certified Energy Practitioners (NABCEP®), and is ... respected and well established national certification organization for renewable energy professionals. Designation as ...
(Date:7/3/2015)... ... July 03, 2015 , ... Brendon ... 2nd creating a buzz of media attention. In an effort to spread the ... Tiffany Hendricks. , "These days many people are feeling overwhelmed by stress and ...
(Date:7/3/2015)... SC (PRWEB) , ... July ... ... has announced the sessions and speaker lineup for its 2015 Annual ... taking place August 6-8, 2015 at the Renaissance Orlando at SeaWorld in ...
(Date:7/3/2015)... ... July 03, 2015 , ... Renowned rhinoplasty surgeon and ... 2016 Dallas Rhinoplasty Symposium . To be held from March 4th - 6th, ... held at the Westin Galleria Dallas. , Designed to take participants from the basic ...
Breaking Medicine News(10 mins):Health News:New Advancement in Treatment of Chronic Neck Pain 2Health News:New Advancement in Treatment of Chronic Neck Pain 3Health News:Local Solar Professional Earns Industry's Most Prestigious Certification 2Health News:Local Solar Professional Earns Industry's Most Prestigious Certification 3Health News:High Performance Academy - Review Of Brendon Burchard's New High Performance Training Program Released 2Health News:High Performance Academy - Review Of Brendon Burchard's New High Performance Training Program Released 3Health News:RNS Announces Sessions and Speaker Lineup for the 2015 Annual Conference of the Rheumatology Nurses Society 2Health News:RNS Announces Sessions and Speaker Lineup for the 2015 Annual Conference of the Rheumatology Nurses Society 3Health News:Dr. Rod J. Rohrich Announces the Dates for 2016 Dallas Rhinoplasty Symposium 2Health News:Dr. Rod J. Rohrich Announces the Dates for 2016 Dallas Rhinoplasty Symposium 3
... chief of Renal Medicine and director of the Nephrology ... of medicine at Boston University School of Medicine (BUSM) ... Castle Connolly Medical Ltd. , The America,s Top Doctors ... a trusted and authoritative resource for identifying top doctors ...
... To improve the quality of the rapidly expanding array ... entered into a Memorandum of Understanding (MOU) with the ... for Biological Standards and Control (NIBSC) of the United ... plants or animals, rather than those created in a ...
... related to quality of marriage relationship, , , THURSDAY, Dec. ... poorer outcomes for women with breast cancer, a new ... in troubled marriages had higher levels of stress, less ... of illness than women who reported good marriages. ...
... men with chronic prostatitis, a painful disorder of the ... symptoms in recently diagnosed men who had not been ... trial sponsored by the National Institute of Diabetes and ... Institutes of Health (NIH). The study is to be ...
... Society has worked out new guidelines for the diagnosis ... Malignant melanoma is responsible for 90% of deaths from ... last 30 years and UV radiation is thought to ... , Claus Garbe of Tbingen University and his ...
... time with kids is one option to consider , , THURSDAY, ... be important considerations when you,re looking for children,s Christmas gifts, ... Philadelphia. , "Parents often feel like they have to ... chairman and professor of occupational therapy, said in a university ...
Cached Medicine News:Health News:Marital Distress May Affect Breast Cancer Recovery 2Health News:Common treatment for chronic prostatitis fails to reduce symptoms 2Health News:'Hot' Toys May Not Be the Best Present 2
(Date:7/3/2015)... 3, 2015 Un fournisseur ... que sont l,hypertension, le diabète et les troubles ... éducatives gratuites et d,une conférence majeure dédiée à ... ) , Les formations ... Prendre en charge l,hypertension en ligne ...
(Date:7/3/2015)... -- Obsidian HDS, the developer of PharmaShine ( www.pharmashine.com ... of data on pharmaceutical and device industry payments to ... 2014 Open Payments General and Research data released by ... data disclosed on Open Payments for 2014 includes information ... $6.49 billion and is the largest public disclosure of ...
(Date:7/2/2015)... Chine, 3 juillet 2015 BGI a annoncé ... débit de l,ADN situé à Hong ... l,American College of Pathologists  (Collège des pathologistes américains, ... Hong Kong constituent le premier ... recevoir la certification du CAP en Chine, car ...
Breaking Medicine Technology:Lutter contre trois maladies chroniques majeures en Amérique latine grâce à la formation médicale 2Lutter contre trois maladies chroniques majeures en Amérique latine grâce à la formation médicale 3New Open Payments (Sunshine Act) Data Now Searchable on PharmaShine 2BGI obtient la certification du Collège des pathologistes américains (CAP) 2
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
Medicine Products: