Navigation Links
Intake of Polyphenol Speeds Up Fatty Acid Catabolism

A new study has found that polyphenols, dietary substances from vegetables, fruits and green tea, bring about a change in the energy metabolism by increasing the fatty acid breakdown and influence the glucose use in fat cells as they can stimulate energy-sensing regulatory protein SIRT1.

Polyphenols are substances of plant origin that occur in numerous fruits and vegetables. Due to their possible health effect, polyphenols are currently sold as nutritional supplements.

The study was conducted by Vincent de Boer at RIKILT - Institute of Food Safety in Wageningen, Netherlands.

Much research into the health effects of polyphenols is carried out in vitro. However in the body, polyphenols are quickly and easily converted into polyphenol metabolites.

As part of the study, Boer examined rats to study the mechanisms and effects of a polyphenol-rich diet. Relevant polyphenol metabolites that are found in humans called Quercetin were also examined.

Quercetin is a polyphenol that is highly abundant in the human diet, such as onions, apples and tea.

Boer found that lung cells had a greater fatty acid catabolism if the rats constantly received quercetin in their feed.

The energy-sensing protein SIRT1 is an important regulatory protein that can prolong the life span of model organisms such as yeast and fruit flies. In humans, SIRT1 is possibly involved in the regulation of energy use.

Boer found that the SIRT1 activity can be stimulated by various polyphenols, particularly those from green tea stimulated the activity of isolated SIRT1. The quercetin molecule also did this, but an important human quercetin metabolite had the opposite effect. Therefore in intestinal cells, quercetin had no effect on the activity of SIRT1.

In experiments with fat cells, both quercetin and a quercetin metabolite were found to change the glucose use in the fat cell.

Boer concluded that a change in the energy regulation might be an important process for the realisation of possible health effects of polyphenols in the food. This provides new starting points for further research into the molecular mechanisms of polyphenols. This will allow the health effects of polyphenols to be accurately described.


'"/>




Related medicine news :

1. Dangers of Low Calcium Intake
2. Caffeine Intake May reduce Insulin Sensitivity
3. Robo-Dog To Monitor Your Calorie Intake
4. Intake Of Processed Meat And Fat Associated With Pancreatic Cancer
5. Excess Intake of Alcohol Results in Permanent DNA Damage.
6. Intake of a healthy and balanced diet: miracle for old people.
7. Newborns Affected By Antidepressant Intake Of Mothers
8. Salt & Its Intake Causes a Strong debate In UK
9. Pre-eclampsia Pronounced With Intake of Vitamins in Large Doses
10. Viewing TV During Lunch Affects Childrens Food Intake
11. TV Viewing Increases Intake of Junk Food
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/2/2016)... , ... December 02, 2016 , ... Center for Autism ... caregivers of those affected by autism spectrum disorder (ASD) and other developmental disabilities. The ... Maine, will give parents and other caregivers the opportunity to share stories and advice, ...
(Date:12/2/2016)... ... December 02, 2016 , ... Mediaplanet’s newest campaign, ... standing as living proof that attitude and determination can combine into the most ... spike around the holidays. This campaign will offer patients a new-found hope, by ...
(Date:12/2/2016)... ... December 02, 2016 , ... CloudLIMS.com, a class-leading provider of ... Lite. CloudLIMS Lite helps biobanks, clinical, research and testing laboratories keep track of ... new version is a faster and a more efficient product, allowing batch processing ...
(Date:12/2/2016)... ... ... Rijuven Corp launches rejiva ( http://www.rejiva.com ), a unique wearable technology that measures ... on the market can deliver all that rejiva can. , “Rejiva promotes relaxation and ... than the usual heart rate and steps taken”, adds Evens Augustin, CEO of Rijuven. ...
(Date:12/2/2016)... ... 02, 2016 , ... On November 24th, 2016, Thanksgiving morning, ... different sites throughout Miami-Dade and Broward counties. This is the largest meal delivery ... Thanksgiving morning by putting together individual meals via assembly lines and passing them ...
Breaking Medicine News(10 mins):
(Date:12/2/2016)... Research and Markets has announced the addition of the ... to 2022" report to their offering. ... , , The global ultrasound ... is expected to grow at a CAGR of 5.5% during 2016-2022. Based ... during the forecast period, a CAGR of 8.8% in the global market. ...
(Date:12/2/2016)... ATLANTA , Dec. 2, 2016 Quantum ... screening and expert radiologist interpretation directly to women at ... partners with corporations, such as Delta Air Lines and ... cancer screening as a component of wellness initiatives. ... women of SunTrust. It enables them to have a ...
(Date:12/2/2016)... -- In the first ever attempt to include phytocannabinoids ... C. sativa, the Hebrew University in Jerusalem, the University ... , the Universita` del Piemonte Orientale and Phytoplant Research ... unified inventory of phytocannabinoids of different botanical origin. ... chemical and structural diversity of phytocannabinoids. As a result ...
Breaking Medicine Technology: