Navigation Links
Insulin Therapy Shown to Treat Early Experimental Diabetic Retinopathy

Researchers will present study results that indicate that subconjunctivally delivered insulin ameliorates degenerative and inflammatory responses in diabetic rat retinas at the Association for Research in Vision and Ophthalmology (ARVO) 2007 Annual Meeting in Fort Lauderdale, Fla. The presentation will take place on Thursday, May 10 from 10:45 a.m. to 12:30 p.m. in Hall B/C of the Greater Fort Lauderdale/Broward County Convention Center.

Regular human insulin in doses ranging from 0.01U to 1U was injected subconjunctivally in control and 1 month diabetic male Sprague Dawley (SD) rats. The biological effects of subconjunctival insulin on the retina were analyzed using immunoblotting, kinase assays and immunohistochemical analysis. Additionally, insulin-loaded hydrogels were designed for subconjunctival implantation to provide low levels of insulin to the retina for prolonged periods. The hydrogels were engineered to be thermoresponsive and hydrolytically degradable, and their pharmacokinetic and pharmacodynamic properties were studied in vitro and in vivo using R28 cells in culture and SD rats respectively.

Lead researcher Ravi S.J. Singh, MD, of the Pennsylvania State College of Medicine in Hershey, Penn., reports that low dose periocular delivery of insulin to the retina of diabetic rats does not alter blood glucose levels and may treat early diabetic retinopathy.


Page: 1

Related medicine news :

1. Link between birth weight and Insulin Resistance
2. Easier Methods Required to Screen Insulin Resistance
3. Easier Methods Required to Screen Insulin Resistance
4. Insulin Resistance Linked To Difference In Gender
5. Adopting Easier Methods To Screen Insulin Resistance
6. Another Alternative For Diabetics On Insulin
7. Understanding Insulin Resistance
8. Caffeine Intake May reduce Insulin Sensitivity
9. Junk Food Causes High Level Of Insulin Resistance In Children
10. Increasing Insulin Response In Type 2 Diabetics With New Protein Mixture
11. Elevated Insulin Levels To Influence Levels Of Inflammatory Markers
Post Your Comments:

(Date:11/29/2015)... Angeles, Ca (PRWEB) , ... November 29, 2015 , ... ... the American Board of Ophthalmology on November 25th 2015. Peer Certification by ... the field of his specialty. Certification in Ophthalmology is first obtained after the completion ...
(Date:11/29/2015)... ... 29, 2015 , ... Key Housing, a top-rated corporate housing service for the ... apartment community: Epic. In showcasing this featured apartment community in San Jose, Key Housing ... market to efficiently find housing suitable to their needs by showcasing quality housing. , ...
(Date:11/28/2015)... ... November 28, 2015 , ... Pixel Film Studios is back again with ... the possibilities are endless. Users have full control over angle of view, speed method, ... users are sure to get heads to turn. , ProPanel: Pulse offers fully customizable ...
(Date:11/27/2015)... ... ... The rapid speed at which Americans are aging is ... needed, especially with Alzheimer’s, dementia and other cognitive conditions becoming more prevalent. Health ... of this equation: 80 percent of medical care occurs in the home, by ...
(Date:11/27/2015)... ... November 27, 2015 , ... The ... of USA Today in Atlanta, Dallas, New York, Minneapolis, South Florida, with a ... component is distributed nationally, through a vast social media strategy and across a ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... 26 november 2015 AAIPharma Services ... geplande investering aan van ten minste $15,8 ... en het mondiale hoofdkantoor in ... resulteren in extra kantoorruimte en extra capaciteit ... groeiende behoeften van de farmaceutische en biotechnologische ...
(Date:11/26/2015)... 2015 Research and Markets ( ) has ... Market Outlook to 2019 - Rise in Cardiac Disorders and ... report to their offering. Boston ... scientific and others. --> The ... Boston scientific and others. ...
(Date:11/26/2015)... November 26, 2015 ... addition of the  "2016 Future Horizons ... Cell Surface Testing Market: Supplier Shares, ... their offering.  --> ... the  "2016 Future Horizons and Growth ...
Breaking Medicine Technology: