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Insecticide and Repellent Combo Effective in Eliminating Malarial Mosquitoes

icity of harbouring two different forms of Anopheles gambiae. The first appears in May and June in the rice-fields. It shows no resistance to pyrethroids. The second emerges in September and October in puddles left by monsoon rains. These do show resistance to these insecticides.

As expected, the usual pyrethroid-treated nets turned out to be effective only against non-resistant mosquitoes of the first population. Conversely, the nets pre-soaked with non-pyrethroidrepellent combinations proved excellent protection for the people of the local villages, whatever the population of mosquitoes present.

Nevertheless, their residual efficacy (about 15 days) in real conditions did not match the researchers expectations. The team consequently envisage working in conjunction with a company able to devise a system for encapsulating the mixture to prolong the residual life of treated mosquito nets.

The efficacy of these mixtures between organophosphates and repellents therefore opens up a new pathway towards controlling pyrethroid-resistant malaria vectors. In the long term, the researchers plan to test their method on mosquitoes resistant to two other types of insecticide utilized against malaria transmission: organophosphates and carbamates.


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