( Researchers have revealed that combinin...)Insecticide and Repellent Combo Effective in Eliminating Malarial Mosquitoes,Health

Researchers have revealed that combining a non-pyrethroid insecticide, propoxur, and a repellent, N,N-diethyl toluamide may prove to be an effective insecticide-repellent synergy against mosquitoes responsible for malaria transmission to humans.

A combination of the two had proved to be much more effective than the straightforward addition of their respective properties. Mosquito nets soaked with this mixture had a lethal power and irritant effect that inhibited the mosquitoes from biting. Moreover, the mosquitoes are hit by a powerful paralysing action, known as the knockdown effect, on contact with the mixture.

The mortality rates determined were satisfactory, in that they equalled those obtained by using deltamethrin, a commonly used synthetic pyrethroid, highly effective against mosquitoes.

The researchers tested two mixtures composed of a non-pyrethroid insecticide of the organophosphate family, combined with either a standard repellent, DEET, or with a new-generation synthetic repellent. Both of these mixtures show a strong synergy in the resulting lethal and paralysing effects on the mosquitoes. However, only the association between the insecticide and the standard repellent produced a synergistic effect that inhibited the mosquito from taking its blood feed.

A synergistic effect was also observed with regard to the treatments residual efficacy, which is several months longer than that of either agent applied alone. The advantage of the synergistic property of these combinations is enhanced by the fact that it significantly reduced the necessary effective doses against the mosquitoes (about 6 times that of the insecticide applied alone), to attain an efficacy equivalent to that of deltamethrin.

The nets treated with the two mixtures in the laboratory were subsequently tested in field trials, in the rice-growing area 40 km North of Bobo-Dioulasso, in Burkina Faso. This area has the specif
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